o-demethyltramadol has been researched along with ultram in 4 studies
| Studies (o-demethyltramadol) | Trials (o-demethyltramadol) | Recent Studies (post-2010) (o-demethyltramadol) | Studies (ultram) | Trials (ultram) | Recent Studies (post-2010) (ultram) |
|---|---|---|---|---|---|
| 6 | 0 | 3 | 29 | 0 | 6 |
| Protein | Taxonomy | o-demethyltramadol (IC50) | ultram (IC50) |
|---|---|---|---|
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.3255 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.055 | |
| Mu-type opioid receptor | Homo sapiens (human) | 7.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abolin, C; Hewitt, MC; Koch, P; Shao, L; Varney, M | 1 |
| Bakale, R; Bhongle, N; Currie, M; Fang, K; Grover, P; Hewitt, M; Jerussi, TP; Koch, P; Malcolm, S; Ribe, S; Senanayake, C; Shao, L; Wu, F | 1 |
| Bidlack, JM; Bu, Y; Cohen, DJ; Lou, R; Lu, Q; VanAlstine, MA; Wentland, MP | 1 |
| Andrews, JS; Green, B; Maddaford, S; Rakhit, S; Renton, P | 1 |
4 other study(ies) available for o-demethyltramadol and ultram
| Article | Year |
|---|---|
Derivatives of tramadol for increased duration of effect.
Topics: Analgesics, Opioid; Animals; Binding Sites; Codeine; Models, Chemical; Morphine; Pain; Rats; Time Factors; Tramadol | 2006 |
In vitro and in vivo evaluation of O-alkyl derivatives of tramadol.
Topics: Analgesics, Opioid; Animals; Humans; Microsomes, Liver; Molecular Structure; Pain; Protein Binding; Rats; Structure-Activity Relationship; Tramadol | 2008 |
Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.
Topics: Amides; Analgesics, Opioid; Humans; Protein Binding; Receptors, Opioid; Structure-Activity Relationship; Tramadol | 2009 |
NOpiates: Novel Dual Action Neuronal Nitric Oxide Synthase Inhibitors with μ-Opioid Agonist Activity.
Topics: | 2012 |