o-demethyltramadol has been researched along with u-50488 in 3 studies
Studies (o-demethyltramadol) | Trials (o-demethyltramadol) | Recent Studies (post-2010) (o-demethyltramadol) | Studies (u-50488) | Trials (u-50488) | Recent Studies (post-2010) (u-50488) |
---|---|---|---|---|---|
150 | 34 | 73 | 1,664 | 3 | 209 |
6 | 0 | 3 | 1,664 | 3 | 209 |
Protein | Taxonomy | o-demethyltramadol (IC50) | u-50488 (IC50) |
---|---|---|---|
Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0027 | |
Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.7171 | |
Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0958 | |
Kappa-type opioid receptor | Homo sapiens (human) | 0.0537 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Heller, NM; Maher, DP; Walia, D | 1 |
Bidlack, JM; Bu, Y; Cohen, DJ; Lou, R; Lu, Q; VanAlstine, MA; Wentland, MP | 1 |
Fu, W; Huang, H; Li, W; Liu, J; Wang, W; Wang, Y; Xu, X; Zhu, C | 1 |
3 other study(ies) available for o-demethyltramadol and u-50488
Article | Year |
---|---|
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol | 2019 |
Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.
Topics: Amides; Analgesics, Opioid; Humans; Protein Binding; Receptors, Opioid; Structure-Activity Relationship; Tramadol | 2009 |
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)-N-phenylpiperidine-1-carboxamide as novel potent analgesic.
Topics: Analgesics; Animals; Female; Ligands; Mice; Models, Molecular; Pain; Piperidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2020 |