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o-4-methylthymine and o-(6)-methylguanine

o-4-methylthymine has been researched along with o-(6)-methylguanine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's13 (56.52)18.2507
2000's2 (8.70)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dosanjh, MK; Essigmann, JM; Samson, L; Sassanfar, M1
Anderson, MW; Belinsky, SA; Devereux, TR1
Essigmann, JM; Singer, B1
Martel-Planche, G; Mironov, NM; Montesano, R; Swann, PF; Wild, CP1
Cawkwell, L; Georgiadis, P; Margison, GP; Patel, D; Potter, PM; Swann, PF; Wilkinson, MC1
Bromley, M; Fan, CY; Fida, S; O'Connor, PJ; Saffhill, R1
Graves, RJ; Li, BF; Swann, PF1
Dolan, ME; Morimoto, K; Pegg, AE; Scicchitano, D1
Kalnik, M; Li, BF; Patel, DJ; Swann, PF1
Dolan, ME; Pegg, AE; Scicchitano, D; Singer, B1
Ihara, K; Kawate, H; Kohda, K; Sakumi, K; Sekiguchi, M1
Huh, N; Kang, H; Konishi, C; Kuroki, T2
Kleibl, K; Laval, F; Zak, P1
Harris, LC; Margison, GP1
Drummond, JT; Duckett, DR; Lilley, DM; Modrich, P; Murchie, AI; Reardon, JT; Sancar, A1
Altshuler, KB; Essigmann, JM; Hodes, CS1
Clarke, ND; Paalman, SR; Sung, C1
Hughes, SH; Moschel, RC; Pauly, GT1
Kooistra, R; Lohman, PH; Margison, GP; Pastink, A; Watson, AJ; Zonneveld, JB1
Encell, LP; Loeb, LA1
Moschel, RC; Pauly, GT1
Duncan Lyngdoh, RH; Premila Devi, S; Salam, T1

Reviews

1 review(s) available for o-4-methylthymine and o-(6)-methylguanine

ArticleYear
Site-specific mutagenesis: retrospective and prospective.
    Carcinogenesis, 1991, Volume: 12, Issue:6

    Topics: Animals; DNA; DNA Damage; Guanine; Humans; Mutagenesis; Neoplasms; Thymine

1991

Other Studies

22 other study(ies) available for o-4-methylthymine and o-(6)-methylguanine

ArticleYear
Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases.
    The Journal of biological chemistry, 1991, Feb-15, Volume: 266, Issue:5

    Topics: Base Sequence; Carcinogens; DNA Damage; DNA Repair; Escherichia coli; Guanine; Humans; Methyltransferases; Molecular Sequence Data; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Saccharomyces cerevisiae; Thymine

1991
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: Animals; Base Sequence; Codon; Dimethylnitrosamine; DNA; Drug Resistance; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Molecular Sequence Data; Mutation; Nitrosamines; Proto-Oncogenes; Thymine; Time Factors

1991
Measurement of the removal of O6-methylguanine and O4-methylthymine from oligodeoxynucleotides using an immunoprecipitation technique.
    Analytical biochemistry, 1989, Nov-15, Volume: 183, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Base Sequence; Chromatography, High Pressure Liquid; Guanine; Humans; Male; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Precipitin Tests; Rats; Thymine

1989
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
    Nucleic acids research, 1989, Nov-11, Volume: 17, Issue:21

    Topics: Alkylating Agents; Amino Acids; Chromatography, High Pressure Liquid; Deoxyribonucleotides; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Guanine; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine

1989
Phenobarbital: a non-genotoxic agent which induces the repair of O6-methylguanine from hepatic DNA.
    Carcinogenesis, 1988, Volume: 9, Issue:11

    Topics: 2-Acetylaminofluorene; Animals; DNA Repair; Guanine; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Phenobarbital; Rats; Thymine

1988
Repair of synthetic oligonucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine, by O6-alkylguanine-DNA alkyltransferase.
    IARC scientific publications, 1987, Issue:84

    Topics: Animals; Chromatography, High Pressure Liquid; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine

1987
Specificity of O6-alkylguanine-DNA alkyltransferase.
    IARC scientific publications, 1987, Issue:84

    Topics: Alkylation; Animals; Cattle; DNA Repair; Guanine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; RNA, Ribosomal; RNA, Transfer; Substrate Specificity; Thymine

1987
Synthesis and structural studies by nuclear magnetic resonance of dodecadeoxynucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine.
    IARC scientific publications, 1987, Issue:84

    Topics: Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymine

1987
Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.
    Biochemical and biophysical research communications, 1984, Aug-30, Volume: 123, Issue:1

    Topics: Animals; DNA Repair; Escherichia coli; Guanine; Liver; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Poly T; Polydeoxyribonucleotides; Rats; Thymine

1984
Mouse methyltransferase for repair of O6-methylguanine and O4-methylthymine in DNA.
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: 3T3 Cells; Animals; Base Sequence; DNA Repair; DNA, Complementary; Guanine; HeLa Cells; Humans; Immunoblotting; Intracellular Fluid; Methylnitronitrosoguanidine; Methyltransferases; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity; Thymine

1995
Detection of O6-methylguanine, O4-methylthymine and O4-ethylthymine in human liver and peripheral blood leukocyte DNA.
    Carcinogenesis, 1995, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Autopsy; DNA; DNA Adducts; Female; Guanine; Humans; Leukocytes; Liver; Male; Middle Aged; Thymine

1995
Repair of O6-methylguanine and O4-methylthymine by the human and rat O6-methylguanine-DNA methyltransferases.
    The Journal of biological chemistry, 1994, Jan-07, Volume: 269, Issue:1

    Topics: Animals; DNA; DNA Repair; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Thymine

1994
A highly sensitive and specific method for quantitation of O-alkylated DNA adducts and its application to the analysis of human tissue DNA.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Alkylating Agents; Alkylation; Chromatography, High Pressure Liquid; DNA; DNA Damage; Guanine; Humans; Leukocytes; Phosphorus Radioisotopes; Precipitin Tests; Sensitivity and Specificity; Thymine

1993
Expression in mammalian cells of the Escherichia coli O6 alkylguanine-DNA-alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas.
    British journal of cancer, 1993, Volume: 67, Issue:6

    Topics: Animals; Bacterial Proteins; Base Sequence; Cell Survival; Clone Cells; Cricetinae; Drug Resistance; Escherichia coli; Fibroblasts; Gene Expression; Guanine; Lung; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection

1993
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jun-25, Volume: 93, Issue:13

    Topics: Adenosine Triphosphatases; Bacterial Proteins; Base Composition; Base Sequence; Cisplatin; Dinucleoside Phosphates; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Humans; Molecular Sequence Data; MutS DNA Mismatch-Binding Protein; Protein Binding; Thymine

1996
Intrachromosomal probes for mutagenesis by alkylated DNA bases replicated in mammalian cells: a comparison of the mutagenicities of O4-methylthymine and O6-methylguanine in cells with different DNA repair backgrounds.
    Chemical research in toxicology, 1996, Volume: 9, Issue:6

    Topics: Animals; CHO Cells; Cricetinae; DNA; DNA Repair; Genetic Markers; Genetic Vectors; Guanine; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Sequence Analysis; Thymine; Transfection

1996
Specificity of DNA repair methyltransferases determined by competitive inactivation with oligonucleotide substrates: evidence that Escherichia coli Ada repairs O6-methylguanine and O4-methylthymine with similar efficiency.
    Biochemistry, 1997, Sep-16, Volume: 36, Issue:37

    Topics: Bacterial Proteins; Binding, Competitive; Cloning, Molecular; DNA Repair; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Peptide Fragments; Thymine; Transcription Factors

1997
Comparison of mutagenesis by O6-methyl- and O6-ethylguanine and O4-methylthymine in Escherichia coli using double-stranded and gapped plasmids.
    Carcinogenesis, 1998, Volume: 19, Issue:3

    Topics: DNA Methylation; DNA Repair; Escherichia coli; Guanine; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Thymine

1998
Identification and characterisation of the Drosophila melanogaster O6-alkylguanine-DNA alkyltransferase cDNA.
    Nucleic acids research, 1999, Apr-15, Volume: 27, Issue:8

    Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA Repair; DNA, Complementary; Drosophila melanogaster; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Guanine; Humans; Methylnitronitrosoguanidine; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Thymine; Transcription Factors

1999
Enhanced in vivo repair of O(4)-methylthymine by a mutant human DNA alkyltransferase.
    Carcinogenesis, 2000, Volume: 21, Issue:7

    Topics: DNA Damage; DNA Repair; Enzyme Inhibitors; Escherichia coli; Guanine; Humans; Lac Operon; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Point Mutation; Substrate Specificity; Thymine

2000
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
    Chemical research in toxicology, 2001, Volume: 14, Issue:7

    Topics: Base Pair Mismatch; Colonic Neoplasms; Escherichia coli; Genetic Vectors; Guanine; Humans; Kidney; Lac Operon; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection

2001
Molecular criteria for mutagenesis by DNA methylation: Some computational elucidations.
    Mutation research, 2018, Volume: 807

    Topics: Alkylating Agents; Base Pairing; Computational Biology; DNA; DNA Methylation; Guanine; Nucleic Acid Conformation; Thymine

2018