o-(6)-methylguanine has been researched along with mitozolomide in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tisdale, MJ | 1 |
| Capecchi, B; Citti, L; Leuzzi, R; Mariani, L; Piras, A; Rainaldi, G | 1 |
2 other study(ies) available for o-(6)-methylguanine and mitozolomide
| Article | Year |
|---|---|
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Guanine; Humans; Imidazoles; Kinetics; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Methyltransferases; Mice; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide | 1987 |
The sensitization of cells treated with O6-methylguanine to alkylation damage is affected by the number of O6-methylguanine-DNA methyltransferase molecules escaped from inactivation.
Topics: Animals; Catalytic Domain; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Guanine; Humans; Mutagens; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Proteins | 1998 |