o-(6)-methylguanine has been researched along with ethylnitrosourea in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erickson, LC | 1 |
| Den Engelse, L; Scherer, E; Van Den Berg, T; Vermeulen, E; Winterwerp, HH | 1 |
| Dolan, ME; Erickson, LC; Hora, NK; Pegg, AE | 1 |
| Bresnick, E; Ding, R; Eastman, A; Ghosh, K | 1 |
| Rajewsky, MF; Samson, L; Thomale, J | 1 |
| den Engelse, L; Jenner, AA; Scherer, E | 1 |
| Babich, MA; Day, RS; Hurst-Calderone, S; Yarosh, DB | 1 |
| Brent, TP | 1 |
| Singer, B | 1 |
| Capucci, MS; De Groot, A; Hoffmann, ME; Natarajan, AT | 1 |
| Berger, SJ; Donovan, C; Gerson, SL; Varnes, ME | 1 |
| Cunningham, JM; Delaney, CA; Di Matteo, M; Dunger, A; Green, IC; Green, MH | 1 |
| Bailey, JA; Cooper, DP; Deans, B; Elder, RH; Heeran, MC; Jansen, JG; Margison, GP; Mynett, KJ; Rafferty, JA; van Zeeland, AA; Watson, AJ; Weeks, RJ; Wijnhoven, SW; Willington, MA | 1 |
| Branda, RF; Lafayette, AR; Nicklas, JA; O'Neill, JP | 1 |
| Engelbergs, J; Rajewsky, MF; Schweer, T; Thomale, J | 1 |
| Lawley, PD; Warren, W | 1 |
1 review(s) available for o-(6)-methylguanine and ethylnitrosourea
| Article | Year |
|---|---|
The role of O-6 methylguanine DNA methyltransferase (MGMT) in drug resistance and strategies for its inhibition.
Topics: Animals; DNA Repair; Drug Resistance; Ethylnitrosourea; Guanine; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Rats; Streptozocin | 1991 |
15 other study(ies) available for o-(6)-methylguanine and ethylnitrosourea
| Article | Year |
|---|---|
Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea.
Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; DNA Repair; Esophagus; Ethylnitrosourea; Female; Guanine; Immunoenzyme Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Substrate Specificity | 1989 |
Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
Topics: Cell Division; Cell Survival; Cross-Linking Reagents; DNA Damage; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1988 |
DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; DNA Restriction Enzymes; Drug Resistance; Ethylnitrosourea; Female; Genes; Guanine; Humans; Liver; Methyltransferases; Mycophenolic Acid; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transformation, Genetic | 1985 |
Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.
Topics: Alkylation; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Kinetics; Methylnitrosourea; Mutation; Thymine | 1988 |
Immunocytochemical studies on the formation and repair of O6-alkylguanine in rat tissues.
Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Guanine; Immunohistochemistry; Islets of Langerhans; Kidney Glomerulus; Liver; Male; Muscle, Smooth; Precancerous Conditions; Rats; Spermatogonia; Tissue Distribution | 1987 |
Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.
Topics: Cell Survival; DNA Repair; Ethylnitrosourea; Fibroblasts; Guanine; Humans; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity | 1986 |
Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts.
Topics: Antineoplastic Agents; Cell Line; DNA, Neoplasm; Ethylnitrosourea; Guanine; Humans; Kinetics; Leukemia, Lymphoid; Methylnitrosourea; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase | 1984 |
Alkylation of the O6 of guanine is only one of many chemical events that may initiate carcinogenesis.
Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Guanine; Methylnitrosourea; Neoplasms, Experimental | 1984 |
Streptozotocin-induced toxicity in CHO-9 and V79 cells.
Topics: Animals; Cell Cycle; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA; DNA Replication; Ethylnitrosourea; Guanine; Methylnitrosourea; Mutagens; Streptozocin; Thymidine | 1995 |
Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
Topics: Breast Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Ethylnitrosourea; Glutathione; Glutathione Transferase; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase | 1994 |
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability.
Topics: Alkylating Agents; Animals; Cyclic GMP; Ethyl Methanesulfonate; Ethylnitrosourea; Glucose; Guanine; Insulin; Islets of Langerhans; Methyl Methanesulfonate; Methylnitrosourea; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Structure-Activity Relationship | 1995 |
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Dacarbazine; DNA Glycosylases; Erythrocytes; Ethylnitrosourea; Female; Fibroblasts; Guanine; Hypoxanthine Phosphoribosyltransferase; Leukocyte Count; Liver; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutagens; Mutation; N-Glycosyl Hydrolases; Temozolomide | 1998 |
The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents.
Topics: Alkylating Agents; Animals; Base Pairing; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA Primers; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Folic Acid Deficiency; Guanine; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Polymerase Chain Reaction; Thioguanine | 1999 |
DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; DNA; DNA Adducts; DNA Repair; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagens; Mutation; Rats | 2000 |
The removal of alkylation products from the DNA of Escherichia coli cells treated with the carcinogens N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea: influence of growth conditions and DNA repair defects.
Topics: Adenine; Alkylating Agents; Alkylation; Carcinogens; DNA Repair; DNA, Bacterial; Escherichia coli; Ethylnitrosourea; Guanine; Methylation; Methylnitrosourea | 1980 |