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o-(6)-methylguanine and dimethylnitrosamine

o-(6)-methylguanine has been researched along with dimethylnitrosamine in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199047 (66.20)18.7374
1990's20 (28.17)18.2507
2000's3 (4.23)29.6817
2010's1 (1.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brésil, H; Margison, GP; Montesano, R1
Pegg, AE2
Hui, G; Pegg, AE1
Den Engelse, L; Scherer, E; Van Benthem, J; Vermeulen, E; Wild, CP; Winterwerp, HH1
Chen, JS; Guo, ZL; Liu, ZQ; Xiao, Y; Zhu, JQ1
Butler, WH; Fan, CY; O'Connor, PJ1
Keefer, LK; Kleihues, P; Nims, RW; Reist, EJ; Schmerold, I; von Hofe, E1
Hecht, SS; Peterson, LA1
Den Engelse, L; Scherer, E; Van Benthem, J; Vermeulen, E; Wild, CP1
Anderson, MW; Belinsky, SA; Devereux, TR2
Arce, C; Dumenco, LL; Gerson, SL; Norton, K; Wagner, T; Yun, J1
Archer, MC; Chin, W; Cooper, DP; Dai, WD; Lee, V; O'Connor, PJ1
Zhang, PC1
Archer, MC; Catz-Biro, L; Hirani-Hojatti, S; Milligan, JR1
Den Engelse, L; Scherer, E; Van Den Berg, T; Vermeulen, E; Winterwerp, HH1
Bradbrook, C; Charlesworth, JD; Chu, YH; Cooper, DP; Margison, GP; O'Connor, PJ; Styles, J1
Barch, DH; Fox, CC2
Citti, L; Coccia, P; Diomede, L; Mariani, L; Romano, M; Salmona, M1
den Engelse, L; Jenner, AA; Scherer, E1
Cleary, CM; Friedman, S; Parsa, I1
Craddock, VM; Henderson, AR1
Billett, MA; O'Connor, PJ; Ryan, AJ1
Bürkle, V; Danecki, S; Grotzke, J; Schweinsberg, F; von Karsa, L1
Kleihues, P; von Hofe, E1
Devor, D; Kaufman, DG; Kaufmann, WK; Rice, JM; Wenk, ML1
Bosan, WS; Gaworski, CL; MacEwen, JD; Newberne, PM; Shank, RC1
Mikhaĭlenko, VM; Rubenchik, BL1
Carmella, SG; Chung, FL; Hecht, SS; Wang, M1
Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N1
Archer, MC; Silinskas, KC; Zucker, PF1
Likhachev, A; Montesano, R; Planche-Martel, G; Wild, CP1
Margison, GP1
Columbano, A; Ledda, GM; Rajalakshmi, S; Rao, PM; Sarma, DS2
Bresil, H; Cooper, DP; Margison, GP; Montesano, R; O'Connor, PJ; Planche-Martel, G; Smith, RA1
Lijinsky, W; Pegg, AE1
Brésil, H; Margison, GP; Montesano, R; Pegg, AE; Planche-Martel, G2
Archer, MC; Labuc, GE; Silinskas, KC; Zucker, PF1
Chu, YH; Craig, AW; O'Connor, PJ1
Chu, YH; Margison, GP; Maru, GB; O'Connor, PJ1
Bamborschke, S; Kleihues, P; Margison, GP; Maru, GB; O'Connor, PJ1
Mace, R; Swann, PF1
Kerler, R; Rabes, HM; Rode, G; Wilhelm, R1
Bedell, MA; Belinsky, SA; Swenberg, JA1
Kyrtopoulos, SA; Swann, PF1
Kyrtopoulos, SA; Vrotsou, B1
De Brij, RJ; Den Engelse, L; Philippus, EJ1
Lawrence, JF; Leduc, R; Ryan, JJ1
Bennett, RA; Pegg, AE; Perry, W1
Craig, AW; Galbraith, AI; Itzhaki, RF; Margison, GP1
Abanobi, SE; Columbano, A; Mulivor, RA; Rajalakshmi, S; Sarma, DS1
Pegg, AE; Umbenhauer, DR1
Anderson, LM; Chhabra, S; Kyrtopoulos, SA; Souliotis, VL1
Bean, CL; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB1
Archer, MC; Xie, XY1
Anderson, LM; Chhabra, SK; Harbaugh, JW; Jones, AB; Krasnow, SW; Kyrtopoulos, SA; Souliotis, VL1
Hall, J; Montesano, R; Takahashi, S1
Conran, PB; Geil, RG; Morse, MA; Schut, HA; Siglin, JC; Stoner, GD1
D'Ambrosio, SM; Gopalakrishnan, R; Lu, J; Morse, MA; Peterson, LA; Stoner, GD; Wani, G1
Morse, MA; Stoner, GD1
Anderson, LM; Chhabra, SK; Georgiadis, P; Kyrtopoulos, SA; Pletsa, V; Souliotis, VL; Valavanis, C1
Arimoto-Kobayashi, S; Hayatsu, H; Kaji, K; Sweetman, GM1
Crankshaw, DL; Donaldson, EE; Kenney, PJ; Peterson, LA; Thomson, NM1
Blackwood, M; Carlton, PS; Gupta, A; Kresty, LA; Lu, J; Morgan, C; Morse, MA; Stoner, GD1
Deangelo, AB; Hobbie, KR; King, LC; Law, JM; Winn, RN1
Craig, AW; Margison, GP; Ockey, CH; Swindell, JA1
Hu, J; Jiang, J; Ma, F; Zhang, Z1

Reviews

3 review(s) available for o-(6)-methylguanine and dimethylnitrosamine

ArticleYear
Methylated purines formed in DNA by dimethylnitrosamine in rats previously exposed to hepatotoxic and hepatocarcinogenic regimes: effects on the repair of O6-methylguanine.
    Chemico-biological interactions, 1985, Volume: 53, Issue:3

    Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Animals; Dimethylnitrosamine; DNA; DNA Repair; Ethanolamines; Guanine; Liver; Male; Quinoxalines; Rats; Rats, Inbred Strains

1985
Enhanced repair of O6-alkylguanine in mammalian tissues.
    Folia biologica, 1984, Volume: 30 Spec No

    Topics: 2-Acetylaminofluorene; Adenine; Aflatoxin B1; Aflatoxins; Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Hepatectomy; Liver; Methylnitrosourea; Mice; Rats; Rodentia; Species Specificity

1984
DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance.
    Cancer detection and prevention, 1997, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinogens; Carcinogens, Environmental; Dimethylnitrosamine; DNA Adducts; DNA Damage; DNA Methylation; Erythrocebus patas; Ethanol; Female; Guanine; Humans; Leukocytes; Liver; Mice; Mice, Transgenic; Neoplasms; Nitroso Compounds; Procarbazine

1997

Other Studies

68 other study(ies) available for o-(6)-methylguanine and dimethylnitrosamine

ArticleYear
Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.
    Cancer research, 1979, Volume: 39, Issue:5

    Topics: Animals; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats

1979
Dimethylnitrosamine inhibits enzymatic removal of O6-methylguanine from DNA.
    Nature, 1978, Jul-13, Volume: 274, Issue:5667

    Topics: Animals; Cattle; Depression, Chemical; Dimethylnitrosamine; DNA; Guanine; Kidney; Liver; Methylation; Nitrosamines; Rats

1978
Formation and subsequent removal of O6-methylguanine from deoxyribonucleic acid in rat liver and kidney after small doses of dimethylnitrosamine.
    The Biochemical journal, 1978, Sep-01, Volume: 173, Issue:3

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA; Female; Guanine; In Vitro Techniques; Kidney; Liver; Nitrosamines; Proteins; Rats

1978
Accumulation of O6- and 7-methylguanine in DNA of N-nitroso-N-methylbenzylamine-treated rats is restricted to non-target organs for N-nitroso-N-methylbenzylamine-induced carcinogenesis.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Guanine; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution

1992
The effects of Chinese tea on the methylation of DNA by the esophageal carcinogen N-nitrosomethylbenzylamine.
    Biomedical and environmental sciences : BES, 1991, Volume: 4, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Autoradiography; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Guanine; Male; Methylation; Purine Nucleotides; Rats; Rats, Inbred Strains; Tea

1991
Promutagenic lesions persist in the DNA of target cells for nitrosamine-induced carcinogenesis.
    IARC scientific publications, 1991, Issue:105

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA Damage; Guanine; Male; Neoplasms, Experimental; Rats

1991
Beta-deuteration of N-nitrosoethylmethylamine causes a shift in DNA methylation from rat liver to esophagus.
    Carcinogenesis, 1991, Volume: 12, Issue:4

    Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Chromatography; Deuterium; Dimethylnitrosamine; DNA; Esophagus; Guanine; Kidney; Liver; Lung; Male; Methylation; Microsomes, Liver; Nitrosamines; Rats; Rats, Inbred F344

1991
O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Cancer research, 1991, Oct-15, Volume: 51, Issue:20

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Guanine; Hydroxylation; Lung Neoplasms; Methylation; Mice; Nitrosamines

1991
Immunocytochemical localization of DNA adducts induced by a single dose of N-nitroso-N-methylbenzylamine in target and non-target tissues of tumor formation in the rat.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA Repair; DNA, Neoplasm; Guanine; Immunohistochemistry; Male; Methylation; Organ Specificity; Rats; Rats, Inbred Strains; Tissue Distribution

1991
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: Animals; Base Sequence; Codon; Dimethylnitrosamine; DNA; Drug Resistance; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Molecular Sequence Data; Mutation; Nitrosamines; Proto-Oncogenes; Thymine; Time Factors

1991
Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
    Cancer research, 1991, Jul-01, Volume: 51, Issue:13

    Topics: Animals; Dietary Proteins; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Gene Expression; Guanine; Liver; Methylnitrosourea; Methyltransferases; Mice; Mice, Transgenic; O(6)-Methylguanine-DNA Methyltransferase; Time Factors

1991
DNA methylation in specific cells of rat liver by N-nitrosodimethylamine and N-nitrosomethylbenzylamine.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Species Specificity

1991
[The determination of DNA adducts in liver and lung of mice exposed to dimethylnitrosamine].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1990, Volume: 24, Issue:3

    Topics: Animals; Dimethylnitrosamine; DNA; DNA Damage; Female; Guanine; Liver; Lung; Male; Mice

1990
Methylation of DNA by three N-nitroso compounds: evidence for sequence specific methylation by a common intermediate.
    Chemico-biological interactions, 1989, Volume: 72, Issue:1-2

    Topics: Base Sequence; Dimethylnitrosamine; DNA; DNA Restriction Enzymes; Guanine; Methylation; Methylnitrosourea; Nitrosamines; Nitroso Compounds; Plasmids; Polydeoxyribonucleotides

1989
Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea.
    Cancer letters, 1989, Jul-01, Volume: 46, Issue:1

    Topics: Animals; Carcinogens; Cell Nucleus; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; DNA Repair; Esophagus; Ethylnitrosourea; Female; Guanine; Immunoenzyme Techniques; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; Substrate Specificity

1989
Selective inhibition of methylbenzylnitrosamine-induced formation of esophageal O6-methylguanine by dietary ellagic acid in rats.
    Cancer research, 1988, Dec-15, Volume: 48, Issue:24 Pt 1

    Topics: Animals; Benzopyrans; Cattle; Chromatography, High Pressure Liquid; Diet; Dimethylnitrosamine; DNA; Ellagic Acid; Esophagus; Guanine; Male; Methylation; Rats; Rats, Inbred Strains

1988
Liver DNA alkylation after a single carcinogenic dose of dimethylnitrosamine to newborn and adult CFW Swiss mice.
    Chemico-biological interactions, 1988, Volume: 68, Issue:3-4

    Topics: Alkylation; Animals; Animals, Newborn; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Oxidoreductases, N-Demethylating

1988
Immunocytochemical studies on the formation and repair of O6-alkylguanine in rat tissues.
    IARC scientific publications, 1987, Issue:84

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Guanine; Immunohistochemistry; Islets of Langerhans; Kidney Glomerulus; Liver; Male; Muscle, Smooth; Precancerous Conditions; Rats; Spermatogonia; Tissue Distribution

1987
Factors regulating activation and DNA alkylation by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and nitrosodimethylamine in rat lung and isolated lung cells, and the relationship to carcinogenicity.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Alkylation; Animals; Antibodies; Benzoflavones; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Isoenzymes; Lung; Methylation; Nitrosamines; Rats

1988
Visualization of O6-methylguanine in target cell nuclei of dimethylnitrosamine-treated human pancreas by a murine monoclonal antibody.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Carbon Radioisotopes; Cell Nucleus; Dimethylnitrosamine; Guanine; Humans; Mice; Organ Culture Techniques; Pancreas

1987
Dietary zinc deficiency increases the methylbenzylnitrosamine-induced formation of O6-methylguanine in the esophageal DNA of the rat.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Animals; Deficiency Diseases; Dimethylnitrosamine; DNA; Esophageal Neoplasms; Esophagus; Guanine; Male; Mutation; Rats; Rats, Inbred Strains; Zinc

1987
Effect of N-nitrosamines carcinogenic for oesophagus on O6-alkyl-guanine-DNA-methyl transferase in rat oesophagus and liver.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:3

    Topics: Alkylation; Animals; Cysteine; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Esophageal Neoplasms; Esophagus; Guanine; Liver; Liver Neoplasms, Experimental; Methyltransferases; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Protein Biosynthesis; Rats; Rats, Inbred Strains

1986
Selective repair of methylated purines in regions of chromatin DNA.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: Animals; Chromatin; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Male; Methylation; Purines; Rats; Rats, Inbred Strains

1986
Modifying effects of disulfiram on DNA adduct formation and persistence of benzaldehyde in N-nitroso-N-methyl-benzylamine-induced carcinogenesis in rats.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:2

    Topics: Animals; Benzaldehydes; Carcinogens; Dimethylnitrosamine; Disulfiram; DNA Repair; DNA, Neoplasm; Esophagus; Female; Guanine; Hyperplasia; Rats; Respiratory System; Respiratory Tract Neoplasms

1986
Comparative studies on hepatic DNA alkylation in rats by N-nitrosomethylethylamine and N-nitrosodimethylamine plus N-nitrosodiethylamine.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:3

    Topics: Alkylation; Animals; Diethylnitrosamine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Male; Mathematics; Rats; Rats, Inbred F344

1986
Cell cycle-dependent initiation of hepatocarcinogenesis in rats by methyl(acetoxymethyl)nitrosamine.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Dimethylnitrosamine; DNA Repair; DNA Replication; Guanine; Hepatectomy; Hydrocortisone; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors

1987
Methylation of DNA guanine during the course of induction of liver cancer in hamsters by hydrazine or dimethylnitrosamine.
    Carcinogenesis, 1987, Volume: 8, Issue:3

    Topics: Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Hydrazines; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylation; Tissue Distribution

1987
[DNA alkylation during endogenous synthesis of N-nitrosodimethylamine].
    Eksperimental'naia onkologiia, 1987, Volume: 9, Issue:1

    Topics: Alkylation; Animals; Dimethylamines; Dimethylnitrosamine; DNA; DNA Damage; Guanine; Kidney; Liver; Lung; Male; Rats; Sodium Nitrite

1987
Effects of butylated hydroxyanisole on the tumorigenicity and metabolism of N-nitrosodimethylamine and N-nitrosopyrrolidine in A/J mice.
    Cancer research, 1986, Volume: 46, Issue:1

    Topics: Animals; Anisoles; Biotransformation; Butylated Hydroxyanisole; Dimethylnitrosamine; Female; Glutathione; Glutathione Transferase; Guanine; Lung; Lung Neoplasms; Mice; Microsomes; Microsomes, Liver; N-Nitrosopyrrolidine; Nitrosamines

1986
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats

1986
Formation of O6-methylguanine in rat liver DNA by nitrosamines does not predict initiation of preneoplastic foci.
    Carcinogenesis, 1985, Volume: 6, Issue:5

    Topics: Animals; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Precancerous Conditions; Rats; Rats, Inbred Strains

1985
Modulation of repair of O6-methylguanine in parenchymal and nonparenchymal liver cells of rats treated with dimethylnitrosamine.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Alkylation; Animals; Carbon Radioisotopes; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Liver; Liver Neoplasms; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains

1985
Chronic or acute administration of various dialkylnitrosamines enhances the removal of O6-methylguanine from rat liver DNA in vivo.
    Chemico-biological interactions, 1982, Volume: 38, Issue:2

    Topics: Animals; Chromatography, Gel; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Nitrosamines; Purines; Rats; RNA

1982
In vivo replication of carcinogen-modified rat liver DNA: increased susceptibility of O6-methylguanine compared to N-7-methylguanine in replicated DNA to S1-nuclease.
    Biochemical and biophysical research communications, 1980, Jul-31, Volume: 95, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA Replication; Endonucleases; Guanine; Liver; Male; Methylation; Rats; Single-Strand Specific DNA and RNA Endonucleases; Substrate Specificity

1980
Saturation of repair system for O6-methylguanine in rat liver DNA by pretreatment with cyclic nitrosamines.
    Chemico-biological interactions, 1984, Volume: 51, Issue:3

    Topics: Animals; Binding Sites; Cyclization; Dimethylnitrosamine; DNA Repair; Female; Guanine; Liver; Nitrosamines; Rats; Rats, Inbred Strains

1984
Stability and capacity of dimethylnitrosamine-induced O6-methylguanine repair system in rat liver.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA Repair; DNA Replication; Guanine; Kinetics; Liver; Male; Rats; Rats, Inbred Strains

1983
Formation of O6-methylguanine in regenerating rat liver by N-nitrosomethylbenzylamine is not sufficient for initiation of preneoplastic foci.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Guanine; Kinetics; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains

1984
Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.
    British journal of cancer, 1981, Volume: 43, Issue:6

    Topics: Adenine; Aflatoxin B1; Aflatoxins; Animals; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Rats; Stimulation, Chemical

1981
Effects of carcinogens and partial hepatectomy upon the hepatic O6-methylguanine repair system in mice.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell-Free System; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Hepatectomy; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rats; Rats, Inbred Strains

1982
DNA methylation by dimethylnitrosamine in the Mongolian gerbil (Meriones unguiculatus): indications of a deficient, noninducible hepatic repair system for O6-methylguanine.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Animals; Dimethylnitrosamine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; Dose-Response Relationship, Drug; Gerbillinae; Guanine; Liver; Male; Methyltransferases; Time Factors

1983
Formation and subsequent repair of alkylation lesions in tissues of rodents treated with nitrosamines.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 3

    Topics: Alkylation; Animals; Cricetinae; Dimethylnitrosamine; DNA; DNA Repair; Female; Guanine; Hypophysectomy; In Vitro Techniques; Kidney; Liver; Male; Mesocricetus; Rats; Species Specificity; Thyroidectomy

1980
Changes in O6-methylguanine disappearance from rat liver DNA during chronic dimethylnitrosamine administration. A possible similarity between the system removing O6-methylguanine from DNA in rat liver and in Escherichia coli adapted to N-methyl-N'-nitro-N
    Chemico-biological interactions, 1980, Volume: 31, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA; DNA, Bacterial; Enzyme Induction; Escherichia coli; Female; Guanine; Liver; Methylnitronitrosoguanidine; Rats; Time Factors

1980
Dose- and cell cycle-dependent O6-methylguanine elimination from DNA in regenerating rat liver after [14C]dimethylnitrosamine injection.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adenine; Animals; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Guanine; Interphase; Liver; Liver Regeneration; Male; Rats

1982
Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Alkylation; Animals; Cell Separation; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Ethanol; Guanine; Liver; Male; Rats; Rats, Inbred F344

1982
Susceptibility of dimethylnitrosamine induced O6-methylguanine containing regions in in vivo replicated, hybrid rat liver DNA towards S1 nuclease.
    Cancer letters, 1980, Volume: 10, Issue:4

    Topics: Animals; Bromodeoxyuridine; Deoxyribonucleases; Dimethylnitrosamine; DNA; DNA Replication; Guanine; Liver; Male; Methylation; Nucleic Acid Hybridization; Rats

1980
The use of radioimmunoassay to study the formation and disappearance of O6-methylguanine in mouse liver satellite and main-band DNA following dimethylnitrosamine administration.
    Journal of cancer research and clinical oncology, 1980, Volume: 98, Issue:2

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA Repair; DNA, Satellite; Guanine; Liver; Male; Methylguanidine; Mice; Rabbits; Radioimmunoassay

1980
The formation and repair of O6-methylguanine in rat liver nucleolar DNA after dimethylnitrosamine administration studied by radioimmunoassay.
    Chemico-biological interactions, 1981, Volume: 37, Issue:1-2

    Topics: Animals; Cell Nucleolus; Deoxyguanosine; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Radioimmunoassay; Rats; Rats, Inbred Strains

1981
O6-alkylguanine and structural modifications in liver DNA of dialkylnitrosamine-treated rats.
    Cancer letters, 1981, Volume: 13, Issue:3

    Topics: Animals; Dimethylnitrosamine; DNA; DNA Repair; DNA, Single-Stranded; Dose-Response Relationship, Drug; Female; Guanine; Liver; Nitrosamines; Rats; Rats, Inbred Strains

1981
The determination of O6-methyl- and 7-methylguanine in mouse liver DNA from dimethylnitrosamine-treated mice by high-performance liquid chromatography with UV absorbance detection.
    Analytical biochemistry, 1981, Sep-15, Volume: 116, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA; Guanine; Hydrolysis; Liver; Mice; Spectrophotometry, Ultraviolet

1981
Effect of partial hepatectomy on removal of O6-methylguanine from alkylated DNA by rat liver extracts.
    The Biochemical journal, 1981, Jul-01, Volume: 197, Issue:1

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA Repair; Female; Guanine; Hepatectomy; Liver; Liver Regeneration; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Proteins; Rats; Time Factors

1981
Effect of chronic treatment of rats with dimethylnitrosamine on the removal of O6-methylguanine from DNA.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Dimethylnitrosamine; DNA; DNA Repair; Guanine; Kidney; Liver; Lung; Male; Rats; Time Factors

1980
Distribution and repair of O6-methylguanine in different fractions of rat liver DNA after dimethylnitrosamine administration.
    Chemico-biological interactions, 1980, Volume: 29, Issue:3

    Topics: Animals; Chromatin; Dimethylnitrosamine; DNA Repair; DNA, Single-Stranded; Guanine; Liver; Male; Methylation; Nucleic Acid Denaturation; Rats

1980
In vivo replication of hepatic deoxyribonucleic acid of rats treated with dimethylnitrosamine: presence of dimethylnitrosamine-induced O6-methylguanine, N7-methylguanine, and N3-methyladenine in the replicated hybrid deoxyribonucleic acid.
    Biochemistry, 1980, Apr-01, Volume: 19, Issue:7

    Topics: Adenine; Animals; Dimethylnitrosamine; DNA Replication; Guanine; Liver; Male; Nucleic Acid Hybridization; Rats

1980
Metabolism of dimethylnitrosamine and subsequent removal of O6-methylguanine from DNA by isolated rat hepatocytes.
    Chemico-biological interactions, 1981, Volume: 33, Issue:2-3

    Topics: Alkylation; Animals; Dimethylnitrosamine; DNA; Female; Guanine; In Vitro Techniques; Liver; Methylnitrosourea; Rats

1981
Dosimetry of O6-methylguanine in rat DNA after low-dose, chronic exposure to N-nitrosodimethylamine (NDMA). Implications for the mechanism of NDMA hepatocarcinogenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Female; Guanine; Kinetics; Liver; Liver Neoplasms, Experimental; Rats; Rats, Inbred WF; Time Factors; Water Supply

1995
A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells.
    Mutation research, 1995, Volume: 346, Issue:4

    Topics: Alkylating Agents; B-Lymphocytes; Cell Line; Chromosome Aberrations; Dimethylnitrosamine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Erythroid Precursor Cells; Guanine; Humans; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea

1995
Metabolism of N-nitrosomethylbenzylamine by microsomes from perivenous and periportal hepatocytes.
    Cancer letters, 1994, Jun-15, Volume: 81, Issue:1

    Topics: Animals; Carcinogens; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; gamma-Glutamyltransferase; Guanine; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley

1994
O6-methylguanine DNA adduct formation and modulation by ethanol in placenta and fetal tissues after exposure of pregnant patas monkeys to N-nitrosodimethylamine.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: Animals; Dimethylnitrosamine; DNA Adducts; DNA Damage; Erythrocebus patas; Ethanol; Female; Fetus; Guanine; Maternal-Fetal Exchange; Placenta; Pregnancy

1995
Temporal cell-type-specific mRNA expression of O6-methylguanine-DNA methyltransferases in liver of rats treated with dimethylnitrosamine.
    The American journal of pathology, 1996, Volume: 148, Issue:2

    Topics: Administration, Oral; Animals; Base Sequence; Blotting, Northern; Carcinogens; Dimethylnitrosamine; DNA Adducts; Guanine; Immunohistochemistry; In Situ Hybridization; Liver; Male; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Rats; RNA Probes; RNA, Messenger; Time Factors

1996
O6-methylguanine levels and histopathological changes in the rat esophagus and liver following single and repeated administration of N-nitrosomethylbenzylamine.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Dose-Response Relationship, Drug; Esophagus; Guanine; Liver; Male; Rats; Rats, Inbred F344

1996
Mechanism of enhancement of esophageal tumorigenesis by 6-phenylhexyl isothiocyanate.
    Cancer letters, 1997, Jan-15, Volume: 112, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens; Dimethylnitrosamine; Esophagus; Guanine; Isothiocyanates; Male; Rats; Rats, Inbred F344

1997
Isothiocyanates and plant polyphenols as inhibitors of lung and esophageal cancer.
    Cancer letters, 1997, Mar-19, Volume: 114, Issue:1-2

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Dimethylnitrosamine; DNA Methylation; Dose-Response Relationship, Drug; Ellagic Acid; Esophageal Neoplasms; Female; Guanine; Isothiocyanates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrosamines; Rats; Rats, Inbred F344

1997
Mutation and formation of methyl- and hydroxylguanine adducts in DNA caused by N-nitrosodimethylamine and N-nitrosodiethylamine with UVA irradiation.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Bacterial Proteins; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Guanine; Methyltransferases; Mutagenesis; Mutagenicity Tests; Oxidation-Reduction; Plasmids; Salmonella typhimurium; Ultraviolet Rays

1997
Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
    Cancer research, 2001, Aug-01, Volume: 61, Issue:15

    Topics: Alkylating Agents; Animals; Carcinogens; Dimethylnitrosamine; DNA Methylation; DNA Repair; Drug Synergism; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Pyridines

2001
Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Animals; Carcinogens; Chemoprevention; Diet; Dimethylnitrosamine; DNA Adducts; Ellagic Acid; Esophageal Neoplasms; Freeze Drying; Fruit; Guanine; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344

2001
Toward a molecular equivalent dose: use of the medaka model in comparative risk assessment.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:2

    Topics: Animals; Animals, Genetically Modified; Carcinogens; Dimethylnitrosamine; DNA; DNA Adducts; Dose-Response Relationship, Drug; Guanine; Immunohistochemistry; Liver; Male; Models, Biological; Mutagenicity Tests; Mutation; Oryzias; Random Allocation; Rats; Rats, Inbred F344; Rats, Transgenic; Risk Assessment; Water Supply

2009
The effects of a single dose of dimethylnitrosamine in the Chinese hamster and the persistence of DNA alkylation products in selected tissues.
    Carcinogenesis, 1980, Volume: 1, Issue:1

    Topics: Alkylation; Animals; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA; Drinking Water; Guanine; Kidney; Liver; Liver Neoplasms, Experimental; Lung; Male; Organ Specificity

1980
Chromium (VI) potentiates the DNA adducts (O(6)-methylguanine) formation of N-nitrosodimethylamine in rat: implication on carcinogenic risk.
    Chemosphere, 2015, Volume: 139

    Topics: Animals; Carcinogens, Environmental; Chromium; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; DNA Adducts; Drinking Water; Female; Guanine; Liver; Rats; Rats, Wistar; Risk

2015