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o(6)-n-butylguanine and o-(6)-methylguanine

o(6)-n-butylguanine has been researched along with o-(6)-methylguanine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; Golding, BT; Griffin, RJ; Kanugula, S; Lembicz, NK; Newell, DR; Pegg, AE1
Arris, CE; Bentley, J; Boyle, FT; Curtin, NJ; Davies, TG; Endicott, JA; Gibson, AE; Golding, BT; Grant, S; Griffin, RJ; Jewsbury, P; Johnson, LN; Mesguiche, V; Newell, DR; Noble, ME; Tucker, JA; Whitfield, HJ1
Caflisch, A; Dey, F; Huang, D; Kolb, P1
Chambers, RW; Hirani-Hojatti, S; Sledziewska-Gojska, E1
Borowy-Borowski, H; Chambers, RW; Hirani-Hojatti, S; Sledziewska-Gojska, E1
Boyle, JM; Durrant, LG; Margison, GP; Saffhill, R; Wild, CP1
Corsico, CD; Dolan, ME; Pegg, AE1

Other Studies

7 other study(ies) available for o(6)-n-butylguanine and o-(6)-methylguanine

ArticleYear
Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Cell Extracts; Dacarbazine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Guanine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Tumor Cells, Cultured

2000
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
    Journal of medicinal chemistry, 2002, Aug-01, Volume: 45, Issue:16

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Division; Crystallography, X-Ray; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Guanine; Humans; Models, Molecular; Protein Serine-Threonine Kinases; Ribose; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Humans; Models, Molecular; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Quantitative Structure-Activity Relationship; Static Electricity; Thermodynamics

2008
In vivo effect of DNA repair on the transition frequency produced from a single O6-methyl- or O6-n-butyl-guanine in a T:G base pair.
    Molecular & general genetics : MGG, 1988, Volume: 213, Issue:2-3

    Topics: Bacteriophage phi X 174; Base Composition; DNA Repair; DNA Replication; DNA, Viral; Guanine

1988
uvrA and recA mutations inhibit a site-specific transition produced by a single O6-methylguanine in gene G of bacteriophage phi X174.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:21

    Topics: Bacterial Proteins; Bacteriophage phi X 174; Codon; DNA Repair; DNA, Viral; Escherichia coli; Genes, Viral; Guanine; Mutation; Rec A Recombinases

1985
Genetic evidence for nucleotide excision repair of O6-alkylguanine in mammalian cells.
    Journal of cell science. Supplement, 1987, Volume: 6

    Topics: Alkylation; Animals; Cattle; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA; DNA Repair; Guanine; Humans; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Radioimmunoassay; Xeroderma Pigmentosum

1987
Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Cell Division; DNA Repair; Guanine; HeLa Cells; Humans; Lomustine; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors

1985