Page last updated: 2024-08-25

o(6)-methyl-2'-deoxyguanosine and deoxyguanosine

o(6)-methyl-2'-deoxyguanosine has been researched along with deoxyguanosine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199021 (28.77)18.7374
1990's30 (41.10)18.2507
2000's13 (17.81)29.6817
2010's8 (10.96)24.3611
2020's1 (1.37)2.80

Authors

AuthorsStudies
Chen, J; Hall, J; Han, C; Hu, G; Wild, CP1
Dominé, F; Kleihues, P; Ludeke, BI; Ohgaki, H1
Aboul-Azm, T; Badawi, AF; Cooper, DP; Haboubi, NY; Mostafa, MH; O'Connor, PJ1
Cooper, DP; Howell, A; Laidlaw, I; O'Connor, PJ; Potten, CS; Zaidi, SN1
Kleihues, P; Ludeke, BI; Weller, RO; Yamada, Y1
Chae, WG; Chang, CJ; Cooks, RG; Wood, JM1
Devor, D; Kaufman, DG; Kaufmann, WK; MacKenzie, SA; Qaqish, BF; Rice, JM; Smith, GJ; Wenk, ML1
Kleihues, P; Ludeke, BI; Lutz, WK; Meier, I; Ohgaki, H; Schlatter, C1
Itano, K; Kawazoe, Y; Kohda, K; Sawada, N; Yasuda, M1
Bartsch, H; Béréziat, JC; Camus, AM; Hietanen, E; Montesano, R; Shuker, DE; Wild, CP1
Alvi, NK; Foiles, PG; Williams, GM1
Dirsch, OR; Kleihues, P; Koenigsmann, M; Ludeke, BI; Scherer, E1
Adamkiewicz, J; Kan, LS; Rajewsky, MF; Senear, DF; Ts'o, PO; Yuhasz, SC1
Boucheron, JA; Richardson, FC; Skopek, TR; Swenberg, JA1
Wang, JJ1
Myers, KA; O'Connor, PJ; Saffhill, R1
Basu, AK; Essigmann, JM; Harris, CC; Smith, RA; Wilson, VL1
Beland, FA; Delongchamp, RR; Dooley, KL; Sheldon, WG1
Akerkar, SA; Everson, RB; Foiles, PG; Hecht, SS; Miglietta, LM1
Jeltsch, W; Kleihues, P; Koenigsmann, M; Ludeke, B; Schmerold, I; Wiessler, M1
Feng, L; Lu, SX; Luo, FQ; Tian, YA; Zhang, MS1
Feng, L; Lu, SX1
Chapot, B; Montesano, R; Umbenhauer, D; Wild, CP1
Castonguay, A; Foiles, PG; Trushin, N1
Boyle, JM; Huh, N; Kirstein, U; Lu, SH; Montesano, R; Rajewsky, MF; Saffhill, R; Thomale, J; Umbenhauer, D; Wild, CP1
Castonguay, A; Foiles, PG; Hecht, SS; Trushin, N1
Boyle, JM; Saffhill, R; Smart, G; Wild, CP1
Ball, JC; Maher, VM; McCormick, JJ1
Ayres, K; Larson, K; Lindgren, V; Sklar, R; Strauss, B1
Abbott, PJ; Ludlum, DB; Mehta, JR1
Foote, RS; Mitra, S; Pal, BC1
Salih, H; Swann, PF1
Kyrtopoulos, SA; Vrotsou, B1
Cooper, DP; Povey, AC1
O'Connor, PJ; Zaidi, NH1
Ito, N; Montesano, R; Ogawa, K; Shibata, MA; Shirai, T; Takahashi, S; Tsuda, H; Wild, CP1
Cooper, DP; Crowther, D; Lee, SM; Margison, GP; O'Connor, PJ; Thatcher, N1
Cooper, DP; Lee, SM; Margison, GP; O'Connor, PJ; Thatcher, N1
Cooper, DP; Margison, GP; O'Connor, PJ; Potten, CS; Zaidi, NH2
Bowman, ED; Cooper, DP; Kato, S; Petruzzelli, S; Povey, AC; Shields, PG; Weston, A1
Asamoto, M; Iwase, T; Kato, T; Matsumoto, K; Montesano, R; Nagao, S; Ozaki, K; Tsuda, H; Wild, CP1
Awney, HA; Badawi, AF; Mostafa, MH1
Fukushima, S; Kurata, Y; Mizoguchi, M; Montesano, R; Naito, H; Shibata, MA; Tsuda, H; Wild, CP1
Badawi, AF; Cooper, DP; Cooper, R; Doenhoff, MJ; Fallon, P; Mostafa, MH; O'Connor, PJ; Probert, A1
Jain, R; Sharma, M1
Bakhmedova, AA; Dederer, LIu; Gorbacheva, LB; Mel'nik, SIa; Miniker, TD; Sokolova, IS1
Encell, L; Foiles, PG; Gold, B1
Foiles, PG; Hecht, SS; Miglietta, LM; Staretz, ME1
Demopoulos, NA; Stephanou, G; Vlachodimitropoulos, D; Vlastos, D1
Cooper, DP; Harrison, KL; Jukes, R; Shuker, DE1
Badawi, AF; Cooper, DP; Hall, CN; O'Connor, PJ; Povey, AC1
Nikolic, D; Swanson, SM; van Breemen, RB; Yang, Y1
Mirvish, SS; Zhou, L1
Eckert, KA; Hamid, S1
Fang, Q; Kanugula, S; Pegg, AE1
Brink, A; Lutz, U; Lutz, WK; Völkel, W1
Brown, K; Dingley, K; Farmer, PB; Jukes, R; Lamb, JH; Martin, EA; Tompkins, EM; Turteltaub, KW; Ubick, E1
Fang, Q; Guza, R; Pegg, AE; Rajesh, M; Tretyakova, N1
Burns, PA; Gottschalg, E; Scott, GB; Shuker, DE1
Beland, FA; Churchwell, MI; Doerge, DR1
Brown, K; Farmer, PB; Jones, DJ; Lamb, JH; McLuckie, KI; Pearson, HL; Sandhu, JK1
Brink, A; Lutz, WK; Schulz, B; Stopper, H1
Adema, AD; Honeywell, RJ; Peters, GJ; van der Born, K1
Clarke, JM; Cosgrove, LJ; Gerber, JP; Head, RJ; Lockett, TJ; Tan, SL; Williams, DB1
Bird, AR; Conlon, MA; Hu, Y; Le Leu, RK; Nyskohus, L; Topping, DL; Winter, J; Young, GP1
Jitsuzaki, D; Li, Z; Nishioka, T; Onizuka, K; Sasaki, S; Taniguchi, Y1
Khaira, A; McManus, FP; Noronha, AM; Wilds, CJ1
Da Pieve, C; Moore, SA; Sahgal, N; Velasco-Garcia, MN1
Clement, JM; Collins, LB; Nakamura, J; Sharma, V; Swenberg, JA; Zhang, Z1
Bird, AR; Christophersen, CT; Conlon, MA; Gratz, SW; Hu, Y; Humphreys, KJ; Le Leu, RK; Miller, RB; Topping, DL; Winter, JM; Young, GP1
Gowda, AS; Spratt, TE1
Egli, M; Kellum, AH; Nilforoushan, A; Pallan, PS; Stone, MP; Sturla, SJ1

Trials

1 trial(s) available for o(6)-methyl-2'-deoxyguanosine and deoxyguanosine

ArticleYear
Butyrylated starch intake can prevent red meat-induced O6-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial.
    The British journal of nutrition, 2015, Volume: 114, Issue:2

    Topics: Amylose; Animals; Bacteroides; Cattle; Clostridium; Colon; Cooking; Cross-Over Studies; Deoxyguanosine; Diet; Diet Records; DNA Adducts; Double-Blind Method; Energy Intake; Escherichia coli; Feces; Female; Humans; Lactobacillus; Male; Meat; Microbiota; Middle Aged; Ruminococcus; Starch; Zea mays

2015

Other Studies

72 other study(ies) available for o(6)-methyl-2'-deoxyguanosine and deoxyguanosine

ArticleYear
Lack of effects of selenium on N-nitrosomethylbenzylamine-induced tumorigenesis, DNA methylation, and oncogene expression in rats and mice.
    Nutrition and cancer, 1992, Volume: 18, Issue:3

    Topics: Animals; Biological Assay; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; DNA, Neoplasm; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Male; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Wistar; Selenium; Stomach Neoplasms

1992
Modulation of N-nitrosomethylbenzylamine bioactivation by diallyl sulfide in vivo.
    Carcinogenesis, 1992, Volume: 13, Issue:12

    Topics: Allyl Compounds; Animals; Antineoplastic Agents; Biotransformation; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; DNA; Esophagus; Garlic; Liver; Lung; Male; Methylation; Olfactory Mucosa; Plants, Medicinal; Rats; Rats, Inbred F344; Sulfides

1992
Promutagenic methylation damage in bladder DNA from patients with bladder cancer associated with schistosomiasis and from normal individuals.
    Carcinogenesis, 1992, Volume: 13, Issue:5

    Topics: Age Factors; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Egypt; Female; Humans; Male; Methylation; Schistosomiasis haematobia; Sex Factors; Urinary Bladder Neoplasms

1992
Normal human breast xenografts activate N-nitrosodimethylamine: identification of potential target cells for an environmental nitrosamine.
    British journal of cancer, 1992, Volume: 66, Issue:1

    Topics: Animals; Biotransformation; Breast; Deoxyguanosine; Dimethylnitrosamine; DNA; Drug Implants; Estradiol; Female; Humans; Immunohistochemistry; Mice; Mice, Nude; Transplantation, Heterologous

1992
Effects of ethanol and various alcoholic beverages on the formation of O6-methyldeoxyguanosine from concurrently administered N-nitrosomethylbenzylamine in rats: a dose-response study.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: Alcoholic Beverages; Animals; Biotransformation; Carcinogens; Cell Nucleus; Deoxyguanosine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Esophagus; Ethanol; Liver; Male; Methylation; Rats; Rats, Inbred F344

1992
Chemical modification of DNA: quantitation of O6-methyldeoxyguanosine by tandem mass spectrometry.
    Biological mass spectrometry, 1991, Volume: 20, Issue:8

    Topics: Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; Mass Spectrometry

1991
Proliferation of carcinogen-damaged hepatocytes during cell-cycle-dependent initiation of hepatocarcinogenesis in the rat.
    Carcinogenesis, 1991, Volume: 12, Issue:9

    Topics: Animals; Carcinogens; Cell Cycle; Cocarcinogenesis; Deoxyguanosine; Dimethylnitrosamine; DNA Damage; DNA Repair; Guanine; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats; Rats, Inbred F344

1991
DNA methylation in the digestive tract of F344 rats during chronic exposure to N-methyl-N-nitrosourea.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:1

    Topics: Administration, Oral; Animals; Bromodeoxyuridine; Cell Division; Deoxyguanosine; Digestive System; DNA; DNA Damage; Epithelium; Esophagus; Hyperplasia; Immunoblotting; Male; Methylation; Methylnitrosourea; Purines; Rats; Rats, Inbred F344

1991
Dealkylation rates of O6-alkyldeoxyguanosine, O4-alkylthymidine and related compounds in an alkyl-transfer system.
    Chemico-biological interactions, 1991, Volume: 78, Issue:1

    Topics: Alkylation; Benzene Derivatives; Carbon Isotopes; Deoxyguanosine; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Organoselenium Compounds; Selenium; Thymidine

1991
Effects of a high fat diet on liver DNA methylation in rats exposed to N-nitrosodimethylamine.
    Carcinogenesis, 1990, Volume: 11, Issue:12

    Topics: Animals; Deoxyguanosine; Dietary Fats; Dimethylnitrosamine; DNA; Liver; Male; Methylation; Rats; Rats, Inbred Strains

1990
Inhibition of repair of O6-methyldeoxyguanosine and enhanced mutagenesis in rat-liver epithelial cells.
    Mutation research, 1990, Volume: 230, Issue:2

    Topics: Alkyl and Aryl Transferases; Animals; Cells, Cultured; Deoxyguanosine; DNA; DNA Repair; Epithelial Cells; Epithelium; Kinetics; Liver; Male; Methylnitronitrosoguanidine; Mutation; Rats; Rats, Inbred F344; Transferases

1990
Bioactivation of N-nitrosomethylbenzylamine and N-nitrosomethyl-amylamine in oesophageal papillomas.
    Carcinogenesis, 1990, Volume: 11, Issue:9

    Topics: Animals; Autoradiography; Biotransformation; Carbon Radioisotopes; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; Esophageal Neoplasms; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344

1990
Thermodynamic investigation of monoclonal antibody alkylated nucleoside interaction as a model for epitope recognition on nucleic acids.
    Biochemistry, 1987, Apr-21, Volume: 26, Issue:8

    Topics: Alkylation; Animals; Antibodies, Monoclonal; Deoxyguanosine; DNA; Epitopes; Kinetics; Mice; Mice, Inbred BALB C; Models, Biological; Thermodynamics

1987
Formation of O6-methyldeoxyguanosine at specific sites in a synthetic oligonucleotide designed to resemble a known mutagenic hotspot.
    The Journal of biological chemistry, 1989, Jan-15, Volume: 264, Issue:2

    Topics: Alkylation; Deoxyguanosine; Escherichia coli; Genes; Genes, Bacterial; Indicators and Reagents; Methylnitrosourea; Mutation; Oligodeoxyribonucleotides; Pentosyltransferases

1989
[O6-mdGuo demethylation in cells and tissues].
    Shi yan sheng wu xue bao, 1988, Volume: 21, Issue:2

    Topics: Deoxyguanine Nucleotides; Deoxyguanosine; HeLa Cells; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oxidoreductases; Oxidoreductases, O-Demethylating; Substrate Specificity

1988
Repair of alkylated purines in the hepatic DNA of mitochondria and nuclei in the rat.
    Carcinogenesis, 1988, Volume: 9, Issue:2

    Topics: Acid Phosphatase; Alkylation; Animals; Carcinogens; Cell Nucleus; Deoxyguanosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Mitochondrial; Guanosine; Kinetics; Liver; Male; Rats; Rats, Inbred Strains

1988
O6-alkyldeoxyguanosine detection by 32P-postlabeling and nucleotide chromatographic analysis.
    Cancer research, 1988, Apr-15, Volume: 48, Issue:8

    Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; Liver; Male; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains

1988
Circadian variation in the induction of intestinal tumors by N-methyl-N-nitrosourea in male C57BL/6N mice.
    Journal of the National Cancer Institute, 1988, May-04, Volume: 80, Issue:5

    Topics: Adenocarcinoma; Animals; Circadian Rhythm; Deoxyguanosine; DNA; Intestinal Neoplasms; Intestine, Small; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL

1988
Detection of O6-methyldeoxyguanosine in human placental DNA.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Antibodies, Monoclonal; Deoxyguanosine; DNA; Enzyme-Linked Immunosorbent Assay; Female; Humans; Placenta; Smoking

1988
Organ and cell specificity of DNA methylation by N-nitrosomethylamylamine in rats.
    Cancer research, 1988, Oct-01, Volume: 48, Issue:19

    Topics: Animals; Autoradiography; Biotransformation; Deoxyguanosine; DNA; Immunohistochemistry; Male; Methylation; Nitrosamines; Organ Specificity; Rats; Rats, Inbred F344

1988
[O6-methyldeoxyguanosine in DNA of the adjacent epithelium in human esophageal cancer in Linxian County].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1986, Volume: 8, Issue:5

    Topics: Cardia; China; Deoxyguanosine; DNA, Neoplasm; Epithelium; Esophageal Neoplasms; Esophagus; Humans; Stomach Neoplasms

1986
[Modification of esophageal epithelium DNA in the human fetus by N-nitrosomethylbenzylamine (NMBzA)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1987, Volume: 9, Issue:4

    Topics: Carcinogens; Deoxyguanosine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Epithelium; Esophagus; Fetus; Humans

1987
Monitoring of individual human exposure to aflatoxins (AF) and N-nitrosamines (NNO) by immunoassays.
    Journal of cellular biochemistry, 1986, Volume: 30, Issue:2

    Topics: Aflatoxins; Carcinogens; China; Deoxyguanosine; Digestive System Neoplasms; DNA; DNA Repair; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Europe; Humans; Mass Screening; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Philippines

1986
Measurement of O6-methyldeoxyguanosine in DNA methylated by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone using a biotin-avidin enzyme-linked immunosorbent assay.
    Carcinogenesis, 1985, Volume: 6, Issue:7

    Topics: Animals; Avidin; Biotin; Cattle; Cells, Cultured; Deoxyguanosine; DNA; Enzyme-Linked Immunosorbent Assay; Methylation; Methylnitrosourea; Nasal Mucosa; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Thymus Gland; Tissue Distribution

1985
O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer.
    International journal of cancer, 1985, Dec-15, Volume: 36, Issue:6

    Topics: China; Deoxyguanosine; DNA; Esophageal Neoplasms; Esophagus; France; Gastric Mucosa; Germany; Humans; Methyltransferases; Mucous Membrane; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Radioimmunoassay; Risk

1985
Study of DNA methylation by tobacco-specific N-nitrosamines.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Animals; Antibodies; Carcinogens; Cells, Cultured; Deoxyguanosine; Deoxyribonucleosides; DNA; Enzyme-Linked Immunosorbent Assay; Methylation; Mucous Membrane; Nasal Mucosa; Neoplasms, Experimental; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Smoking

1985
Radioimmunoassay of O6-methyldeoxyguanosine in DNA of cells alkylated in vitro and in vivo.
    Carcinogenesis, 1983, Volume: 4, Issue:12

    Topics: Alkylation; Animals; Antibodies; Antibodies, Monoclonal; Antigen-Antibody Complex; Cattle; Deoxyguanosine; DNA; Kidney; Liver; Lymphocytes; Methylnitrosourea; Mice; Plasmacytoma; Radioimmunoassay; Rats; Thymus Gland

1983
Biological effects of incorporation of O6-methyldeoxyguanosine into Chinese hamster V79 cells.
    Mutation research, 1983, Volume: 110, Issue:2

    Topics: Adenosine Deaminase Inhibitors; Animals; Cell Line; Cell Survival; Coformycin; Cricetinae; Cricetulus; Deoxyguanosine; DNA Replication; Female; Ovary

1983
Regulation of the capacity for O6-methylguanine removal from DNA in human lymphoblastoid cells studied by cell hybridization.
    Molecular and cellular biology, 1982, Volume: 2, Issue:8

    Topics: Adenosine; Cell Fusion; Cell Line; Deoxyguanosine; DNA; Drug Resistance; Female; Humans; Hybrid Cells; Karyotyping; Lymphoma; Male; Methylnitronitrosoguanidine; Neoplasms, Experimental

1982
Synthesis of 8-14C-labeled O6-methyldeoxyguanosine and its deoxynucleotide copolymers.
    Biochemistry, 1980, Feb-19, Volume: 19, Issue:4

    Topics: Deoxyguanine Nucleotides; Deoxyguanosine; DNA Polymerase I; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methods; Poly C; Poly T; Polydeoxyribonucleotides; Polyribonucleotides; Structure-Activity Relationship; Substrate Specificity

1980
Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli.
    Biochemical and biophysical research communications, 1980, Nov-28, Volume: 97, Issue:2

    Topics: Deoxyguanosine; Enzyme Induction; Escherichia coli; Guanine; Kinetics; Methylnitronitrosoguanidine; Polydeoxyribonucleotides

1980
Immunoassay of O6-methyldeoxyguanosine in DNA: the use of polyethylene glycol to separate bound and free nucleoside.
    Chemico-biological interactions, 1982, Volume: 41, Issue:2

    Topics: Alkylation; Animals; Antibody Specificity; Cross Reactions; Deoxyguanosine; Dimethylnitrosamine; DNA; Immune Sera; Liver; Male; Polyethylene Glycols; Radioimmunoassay; Rats

1982
The formation and repair of O6-methylguanine in rat liver nucleolar DNA after dimethylnitrosamine administration studied by radioimmunoassay.
    Chemico-biological interactions, 1981, Volume: 37, Issue:1-2

    Topics: Animals; Cell Nucleolus; Deoxyguanosine; Dimethylnitrosamine; DNA Repair; Guanine; Liver; Male; Radioimmunoassay; Rats; Rats, Inbred Strains

1981
The development, validation and application of a 32P-postlabelling assay to quantify O6-methylguanine in human DNA.
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: Chromatography, Thin Layer; Deoxyguanosine; DNA; DNA Damage; Female; Guanine; Humans; Isotope Labeling; Male; Nucleotides; Phosphorus Radioisotopes; Reproducibility of Results

1995
Identification in rat stomach mucosae of a cell population characterized by a deficiency for the repair of O6-methyldeoxyguanosine from DNA.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: Animals; Carcinogens; Deoxyguanosine; DNA; DNA Repair; Duodenum; Gastric Mucosa; Immunohistochemistry; Male; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Rats; Rats, Wistar

1995
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Administration, Oral; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Deoxyguanosine; Disease Progression; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Injections, Intraperitoneal; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1994
Relationships between the formation of O6-methyldeoxyguanosine by 1-p-carboxyl-3,3-dimethylphenyltriazene in DNA and O6-alkylguanine-DNA alkyltransferase in human peripheral leukocytes.
    Cancer research, 1994, Aug-01, Volume: 54, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Deoxyguanosine; DNA Nucleotidyltransferases; DNA, Neoplasm; Female; Guanine; Humans; Leukocytes; Lymphocytes; Male; Melanoma; Middle Aged; Triazenes

1994
Formation and loss of O6-methyldeoxyguanosine in human leucocyte DNA following sequential DTIC and fotemustine chemotherapy.
    British journal of cancer, 1994, Volume: 69, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Deoxyguanosine; DNA; Female; Humans; Leukocytes; Lymphocytes; Male; Middle Aged; Nitrosourea Compounds; Nucleotidyltransferases; Organophosphorus Compounds

1994
Tissue and cell specific methylation, repair and synthesis of DNA in the upper gastrointestinal tract of Wistar rats treated with single doses of N-methyl-N'-nitro-N-nitrosoguanidine.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Animals; Cell Division; Deoxyguanosine; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Duodenum; Esophagus; Gastric Mucosa; Male; Methylation; Methylnitronitrosoguanidine; Methyltransferases; Pylorus; Rats; Rats, Wistar; Stomach

1993
Tissue and cell specific methylation, repair and synthesis of DNA in the upper gastrointestinal tract of Wistar rats treated with N-methyl-N'-nitro-N-nitrosoguanidine via the drinking water.
    Carcinogenesis, 1993, Volume: 14, Issue:10

    Topics: Animals; Deoxyguanosine; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Duodenum; Esophagus; Gastric Mucosa; Jejunum; Male; Methylation; Methylnitronitrosoguanidine; Methyltransferases; Pylorus; Rats; Rats, Wistar; Stomach; Water Supply

1993
Combined micropreparative techniques with synchronous fluorescence spectroscopy or 32P-postlabelling assay for carcinogen-DNA adduct determination.
    IARC scientific publications, 1993, Issue:124

    Topics: Benzo(a)pyrene; Carcinogens; Chromatography, Affinity; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Humans; In Vitro Techniques; Lung; Methods; Phosphorus Radioisotopes; Polycyclic Compounds; Reference Standards; Spectrometry, Fluorescence

1993
Decreased dimethylnitrosamine-induced O6- and N7-methyldeoxyguanosine levels correlate with development and progression of lesions in rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyguanosine; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344

1993
Formation of promutagenic methylation damage in tissue-DNA of mice treated with antischistosomal agents.
    Cancer letters, 1993, Dec-20, Volume: 75, Issue:3

    Topics: Alkylation; Animals; Deoxyguanosine; DNA; DNA Damage; Hycanthone; Kidney; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Oxamniquine; Schistosomicides; Spleen; Trichlorfon; Urinary Bladder

1993
Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:2

    Topics: Adenocarcinoma; Aging; Animals; Bromodeoxyuridine; Deoxyguanosine; DNA; Intestinal Neoplasms; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Splenic Neoplasms; Thymus Neoplasms; Tongue Neoplasms

1993
Promutagenic methylation damage in liver DNA of mice infected with Schistosoma mansoni.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Animals; Deoxyguanosine; DNA; DNA Damage; Female; Liver; Male; Methylation; Mice; Mutation; Schistosoma mansoni; Schistosomiasis mansoni; Sex Factors

1993
Fluorescence postlabeling assay of DNA damage induced by N-methyl-N-nitrosourea.
    Cancer research, 1993, Jun-15, Volume: 53, Issue:12

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Fluorescence; Magnetic Resonance Spectroscopy; Methylnitrosourea

1993
[Modulation of the antitumor activity of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoure a by O(6)-methyl-2'-deoxyguanosine--a new inhibitor of O(6)-alkylguanine-DNA-alkyltransferase].
    Biokhimiia (Moscow, Russia), 1995, Volume: 60, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Division; Deoxyguanosine; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Drug Synergism; Leukemia L1210; Melanoma, Experimental; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1995
The relationship between N-nitrosodimethylamine metabolism and DNA methylation in isolated rat hepatocytes.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: Animals; Carcinogens; Deoxyguanosine; Dimethylnitrosamine; DNA; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley

1996
Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Cancer research, 1997, Jan-15, Volume: 57, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Isothiocyanates; Lung; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344

1997
A comparative study on the effect of MNU on human lymphocyte cultures in vitro evaluated by O6-mdG formation, micronuclei and sister chromatid exchanges induction.
    Cancer letters, 1996, Dec-03, Volume: 109, Issue:1-2

    Topics: Carcinogens; Cells, Cultured; Deoxyguanosine; Humans; Lymphocytes; Methylnitrosourea; Micronucleus Tests; Sister Chromatid Exchange

1996
Detection of concomitant formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine in DNA exposed to nitrosated glycine derivatives using a combined immunoaffinity/HPLC method.
    Chemical research in toxicology, 1999, Volume: 12, Issue:1

    Topics: Animals; Calibration; Carcinogens; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; Glycine; Immunosorbents; Nitroso Compounds; Thymus Gland

1999
Elevated levels of the pro-carcinogenic adduct, O(6)-methylguanine, in normal DNA from the cancer prone regions of the large bowel.
    Gut, 2000, Volume: 47, Issue:3

    Topics: Aged; Alkylation; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Deoxyguanosine; DNA Adducts; Female; Humans; Male; Radioimmunoassay

2000
Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS.
    Analytical chemistry, 2002, Oct-15, Volume: 74, Issue:20

    Topics: Animals; Cattle; Chromatography, Liquid; Deoxyguanosine; DNA; DNA Adducts; Hydrolysis; Indicators and Reagents; Liver; Mass Spectrometry; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet

2002
Inhibition by allyl sulfides and crushed garlic of O6-methylguanine formation in liver DNA of dimethylnitrosamine-treated rats.
    Nutrition and cancer, 2005, Volume: 51, Issue:1

    Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Garlic; Kidney; Liver; Lung; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfides

2005
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate.
    Biochemistry, 2005, Aug-02, Volume: 44, Issue:30

    Topics: Alkylating Agents; Amino Acid Substitution; Animals; Arginine; Base Sequence; Deoxycytosine Nucleotides; Deoxyguanosine; DNA Damage; DNA Polymerase beta; DNA Primers; Glutamic Acid; Lysine; Methionine; Methylnitrosourea; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Substrate Specificity; Templates, Genetic; Thymine Nucleotides

2005
Function of domains of human O6-alkylguanine-DNA alkyltransferase.
    Biochemistry, 2005, Nov-22, Volume: 44, Issue:46

    Topics: Deoxyguanosine; DNA Repair; Escherichia coli; Humans; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Protein Folding; Protein Renaturation; Protein Structure, Tertiary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2005
Simultaneous determination of O6-methyl-2'-deoxyguanosine, 8-oxo-7,8-dihydro-2'-deoxyguanosine, and 1,N6-etheno-2'-deoxyadenosine in DNA using on-line sample preparation by HPLC column switching coupled to ESI-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jan-18, Volume: 830, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Adducts; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:5

    Topics: Acetic Anhydrides; Carbon Radioisotopes; Deoxyguanosine; DNA Adducts; Environmental Monitoring; Humans; Mass Spectrometry; Particle Accelerators

2006
Kinetics of O(6)-methyl-2'-deoxyguanosine repair by O(6)-alkylguanine DNA alkyltransferase within K-ras gene-derived DNA sequences.
    Chemical research in toxicology, 2006, Volume: 19, Issue:4

    Topics: Base Sequence; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Primers; DNA Repair; Genes, ras; Humans; Kinetics; O(6)-Methylguanine-DNA Methyltransferase; Spectrometry, Mass, Electrospray Ionization

2006
Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine DNA adducts: relevance for gastrointestinal cancer.
    Carcinogenesis, 2007, Volume: 28, Issue:2

    Topics: Azo Compounds; Chromatography, Affinity; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Gastrointestinal Neoplasms; Genes, p53; Glycine; Humans; Mutation; Plasmids

2007
Quantification of O6-methyl and O6-ethyl deoxyguanosine adducts in C57BL/6N/Tk+/- mice using LC/MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Nov-21, Volume: 844, Issue:1

    Topics: Animals; Deoxyguanosine; Female; Liver; Male; Mice; Mice, Inbred C57BL; Reference Standards; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2006
Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS).
    Nucleic acids research, 2006, Volume: 34, Issue:22

    Topics: Cell Line; Deoxyguanosine; DNA Adducts; Escherichia coli; Genetic Vectors; Humans; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plasmids; Reference Standards; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transfection

2006
Biological significance of DNA adducts investigated by simultaneous analysis of different endpoints of genotoxicity in L5178Y mouse lymphoma cells treated with methyl methanesulfonate.
    Mutation research, 2007, Dec-01, Volume: 625, Issue:1-2

    Topics: Animals; Cell Line, Tumor; Chromatography, Liquid; Deoxyguanosine; DNA Adducts; DNA Breaks; DNA Methylation; Dose-Response Relationship, Drug; Guanine; Leukemia L5178; Methyl Methanesulfonate; Mice; Models, Biological; Mutagens; Tandem Mass Spectrometry

2007
Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dacarbazine; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Methylation; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Mice; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Piperidines; Pyridines; Temozolomide

2009
Is the tissue persistence of O(6)-methyl-2'-deoxyguanosine an indicator of tumour formation in the gastrointestinal tract?
    Mutation research, 2011, Apr-03, Volume: 721, Issue:2

    Topics: Alkylating Agents; Animals; Azoxymethane; Colonic Neoplasms; Deoxyguanosine; DNA Adducts; Gastrointestinal Tract; Intestinal Neoplasms; Intestine, Small; Male; Methylation; Mutagens; Rats; Rats, Sprague-Dawley; Time Factors

2011
Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:11

    Topics: Animals; Apoptosis; Cell Proliferation; Colon; Deoxyguanosine; Dietary Carbohydrates; Dietary Proteins; DNA Adducts; Feces; Fermentation; Intestine, Large; Male; Meat; Mice; Mice, Inbred C57BL; Mutagens; Starch

2011
An efficient and simple method for site-selective modification of O6-methyl-2'-deoxyguanosine in DNA.
    Chemical communications (Cambridge, England), 2012, Apr-25, Volume: 48, Issue:33

    Topics: Base Sequence; Binding Sites; Deoxyguanosine; DNA; Substrate Specificity

2012
Preparation of covalently linked complexes between DNA and O(6)-alkylguanine-DNA alkyltransferase using interstrand cross-linked DNA.
    Bioconjugate chemistry, 2013, Feb-20, Volume: 24, Issue:2

    Topics: Base Sequence; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Repair; Escherichia coli; Humans; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; O(6)-Methylguanine-DNA Methyltransferase

2013
Development of a liquid chromatography/tandem mass spectrometry method to investigate the presence of biomarkers of DNA damage in urine related to red meat consumption and risk of colorectal cancer.
    Rapid communications in mass spectrometry : RCM, 2013, Nov-15, Volume: 27, Issue:21

    Topics: Animals; Chromatography, Liquid; Colorectal Neoplasms; Cross-Over Studies; Deoxyguanosine; Diet; Diet, Vegetarian; DNA Damage; Guanine; Humans; Limit of Detection; Meat; Tandem Mass Spectrometry

2013
Molecular dosimetry of endogenous and exogenous O(6)-methyl-dG and N7-methyl-G adducts following low dose [D3]-methylnitrosourea exposures in cultured human cells.
    Chemical research in toxicology, 2014, Apr-21, Volume: 27, Issue:4

    Topics: Cells, Cultured; Deoxyguanosine; Dose-Response Relationship, Drug; Guanine; Humans; Methylnitrosourea

2014
DNA Polymerase ν Rapidly Bypasses O
    Chemical research in toxicology, 2016, 11-21, Volume: 29, Issue:11

    Topics: Deoxyguanosine; DNA-Directed DNA Polymerase; Escherichia coli Proteins; Kinetics; Thymidine

2016
Conformation and Pairing Properties of an
    Chemical research in toxicology, 2022, 10-17, Volume: 35, Issue:10

    Topics: Benzimidazoles; Carcinogens; Deoxyguanosine; DNA; DNA Adducts; Nucleic Acid Conformation; Nucleosides; Nucleotides; S-Adenosylmethionine; Xenobiotics

2022