o(6)-benzylguanine and lomeguatrib

o(6)-benzylguanine has been researched along with lomeguatrib in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Eichhorn, U; Hull, WE; Kaina, B; Kliem, HC; Reinhard, J; von der Lieth, CW; Wiessler, M	1
Donnelly, DJ; Kelly, J; Margison, GP; McCormick, JE; McElhinney, RS; McMurry, TB; Middleton, MR; Thatcher, N	1
Middleton, MR; Sabharwal, A	1

Reviews

1 review(s) available for o(6)-benzylguanine and lomeguatrib

Article	Year
Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy. Current opinion in pharmacology, 2006, Volume: 6, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Dacarbazine; DNA Adducts; DNA Methylation; DNA Topoisomerases, Type I; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Guanine; Humans; Irinotecan; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds; Prognosis; Promoter Regions, Genetic; Temozolomide; Topoisomerase I Inhibitors	2006

Article

Year

Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy.

Current opinion in pharmacology, 2006, Volume: 6, Issue:4

Topics: Animals; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Dacarbazine; DNA Adducts; DNA Methylation; DNA Topoisomerases, Type I; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Guanine; Humans; Irinotecan; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds; Prognosis; Promoter Regions, Genetic; Temozolomide; Topoisomerase I Inhibitors

2006

Other Studies

2 other study(ies) available for o(6)-benzylguanine and lomeguatrib

Article	Year
Monosaccharide-linked inhibitors of O(6)-methylguanine-DNA methyltransferase (MGMT): synthesis, molecular modeling, and structure-activity relationships. Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24 Topics: Cell-Free System; Crystallography, X-Ray; Enzyme Inhibitors; Glucosides; Guanine; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Monosaccharides; O(6)-Methylguanine-DNA Methyltransferase; Solubility; Structure-Activity Relationship	2001
O(6)-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts. International journal of cancer, 2000, Jan-15, Volume: 85, Issue:2 Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Guanine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Temozolomide; Transplantation, Heterologous	2000

Article

Year

Monosaccharide-linked inhibitors of O(6)-methylguanine-DNA methyltransferase (MGMT): synthesis, molecular modeling, and structure-activity relationships.

Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24

Topics: Cell-Free System; Crystallography, X-Ray; Enzyme Inhibitors; Glucosides; Guanine; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Monosaccharides; O(6)-Methylguanine-DNA Methyltransferase; Solubility; Structure-Activity Relationship

2001

O(6)-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts.

International journal of cancer, 2000, Jan-15, Volume: 85, Issue:2

Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Guanine; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Temozolomide; Transplantation, Heterologous

2000