Compounds > o(6)-benzylguanine

o(6)-benzylguanine and fotemustine

o(6)-benzylguanine has been researched along with fotemustine in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chinnasamy, N; Fairbairn, LJ; Laher, J; Rafferty, JA; Willington, MA1
Christmann, M; Kaina, B; Lage, H; Pick, M; Schadendorf, D1
Cupissol, D; Cuq, P; Depeille, P; Evrard, A; Montero, JL; Passagne, I; Vian, L; Winum, JY1

Other Studies

3 other study(ies) available for o(6)-benzylguanine and fotemustine

ArticleYear
Modulation of O6-alkylating agent induced clastogenicity by enhanced DNA repair capacity of bone marrow cells.
    Mutation research, 1998, Aug-07, Volume: 416, Issue:1-2

    Topics: Alkyl and Aryl Transferases; Alkylating Agents; Animals; Bone Marrow Cells; Bone Marrow Transplantation; DNA Repair; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression; Guanine; Humans; Male; Mice; Micronucleus Tests; Mutagens; Mutation; Nitrosourea Compounds; Organophosphorus Compounds; Streptozocin

1998
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT.
    International journal of cancer, 2001, Apr-01, Volume: 92, Issue:1

    Topics: Antineoplastic Agents; Azacitidine; Blotting, Southern; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Enzyme Reactivators; Gene Amplification; Gene Expression; Guanine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Tumor Cells, Cultured

2001
Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Carmustine; DNA Damage; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Tumor Cells, Cultured

2003