o(6)-benzylguanine and ethylnitrosourea

o(6)-benzylguanine has been researched along with ethylnitrosourea in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bronstein, SM; Hooth, MJ; Skopek, TR; Swenberg, JA1
Faustman, EM; Kidney, JK1
Berger, SJ; Donovan, C; Gerson, SL; Varnes, ME1
Anver, MR; Lijinsky, W; Moschel, RC; Pegg, AE1
Faustman, EM; Seeley, MR1
Brent, TP; Edwards, CC; Harris, LC; Houghton, PJ; Marathi, UK; Sorrentino, BP; Srivastava, DK; Vanin, EF1
Bibby, MC; Margison, GP; McElhinney, RS; Rafferty, JA; Thompson, MJ1
Gerson, SL; Phillips, WP1
Erickson, LC; Kurpad, C; Maze, R; Pegg, AE; Williams, DA1
Fan, T; Li, S; Sun, G; Zhao, L; Zhong, R1

Other Studies

10 other study(ies) available for o(6)-benzylguanine and ethylnitrosourea

ArticleYear
Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine.
    Cancer research, 1992, Jul-15, Volume: 52, Issue:14

    Topics: Alkylation; Cell Line, Transformed; Cell Survival; DNA Repair; Ethylnitrosourea; Guanine; Humans; Lymphocytes; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype

1992
Modulation of nitrosourea toxicity in rodent embryonic cells by O6-benzylguanine, a depletor of O6-methylguanine-DNA methyltransferase.
    Toxicology and applied pharmacology, 1995, Volume: 133, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; DNA Adducts; Ethylnitrosourea; Female; Guanine; Mesencephalon; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Pregnancy; Rats; Rats, Sprague-Dawley

1995
Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Breast Neoplasms; Carmustine; Cell Line; Cell Survival; Drug Resistance; Ethylnitrosourea; Glutathione; Glutathione Transferase; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase

1994
Effects of inhibition of O6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Ethylnitrosourea; Female; Guanine; Liver; Methylnitrosourea; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344

1994
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured

1998
Retroviral transfer of a bacterial alkyltransferase gene into murine bone marrow protects against chloroethylnitrosourea cytotoxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Bacterial Proteins; Bone Marrow; Carmustine; Enzyme Inhibitors; Escherichia coli Proteins; Ethylnitrosourea; Feasibility Studies; Gene Transfer Techniques; Guanine; Mice; Mice, Inbred CBA; O(6)-Methylguanine-DNA Methyltransferase; Retroviridae; Transcription Factors

1995
Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
    British journal of cancer, 1999, Volume: 79, Issue:9-10

    Topics: Animals; Antineoplastic Agents, Alkylating; Carmustine; Colony-Forming Units Assay; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Ethylnitrosourea; Fluorouracil; Guanine; Humans; Male; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Tumor Stem Cell Assay

1999
Acquired resistance to O6-benzylguanine plus chloroethylnitrosoureas in human breast cancer.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmustine; Drug Resistance, Neoplasm; Drug Synergism; Ethylnitrosourea; Glutathione; Guanine; Humans; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1999
Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma; Ethylnitrosourea; Female; Genetic Vectors; Guanine; Hematopoietic Stem Cells; Humans; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Retroviridae; Tumor Cells, Cultured

1999
Investigations on the effect of O(6)-benzylguanine on the formation of dG-dC interstrand cross-links induced by chloroethylnitrosoureas in human glioma cells using stable isotope dilution high-performance liquid chromatography electrospray ionization tand
    Chemical research in toxicology, 2014, Jul-21, Volume: 27, Issue:7

    Topics: Alkylating Agents; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; DNA; DNA Damage; Ethylnitrosourea; Glioma; Guanine; Humans; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014