o(6)-benzylguanine and allopurinol

o(6)-benzylguanine has been researched along with allopurinol in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baumann, RP; Liu, MC; Luo, MZ; Penketh, PG; Sartorelli, AC; Shyam, K; Zhu, R	1

Other Studies

2 other study(ies) available for o(6)-benzylguanine and allopurinol

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine. Journal of medicinal chemistry, 2011, Nov-10, Volume: 54, Issue:21 Topics: Animals; Antineoplastic Agents, Alkylating; Cell Hypoxia; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Guanine; Humans; Hydrazines; Mice; NADPH-Ferrihemoprotein Reductase; O(6)-Methylguanine-DNA Methyltransferase; Prodrugs; Solubility; Structure-Activity Relationship; Sulfonamides; Xanthine Oxidase	2011

Article

Year

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nature chemical biology, 2007, Volume: 3, Issue:5

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007

4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine.

Journal of medicinal chemistry, 2011, Nov-10, Volume: 54, Issue:21

Topics: Animals; Antineoplastic Agents, Alkylating; Cell Hypoxia; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Guanine; Humans; Hydrazines; Mice; NADPH-Ferrihemoprotein Reductase; O(6)-Methylguanine-DNA Methyltransferase; Prodrugs; Solubility; Structure-Activity Relationship; Sulfonamides; Xanthine Oxidase

2011