o(6)-benzylguanine and 8-hydroxyguanine

o(6)-benzylguanine has been researched along with 8-hydroxyguanine in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Balis, FM; Berg, SL; Cole, DE; Gerson, SL; Godwin, K; Liu, L	1
Ashley, DM; Bigner, DD; Cokgor, I; Colvin, OM; Dolan, ME; Ewesuedo, RB; Friedman, AH; Friedman, HS; Garcia-Turner, AM; Haglund, MM; Herndon, JE; Long, L; McLendon, RE; Moschel, RC; Pegg, AE; Pluda, J; Provenzale, JM; Quinn, JA; Rich, JN; Sampson, J; Stewart, ES; Tourt-Uhlig, S	1
Dolan, ME; Long, L; Moschel, RC	1

Trials

1 trial(s) available for o(6)-benzylguanine and 8-hydroxyguanine

Article	Year
Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Oct-15, Volume: 18, Issue:20 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carmustine; Central Nervous System Neoplasms; Drug Administration Schedule; Glioblastoma; Guanine; Humans; Middle Aged; Neoplasm Recurrence, Local	2000

Article

Year

Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Oct-15, Volume: 18, Issue:20

Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carmustine; Central Nervous System Neoplasms; Drug Administration Schedule; Glioblastoma; Guanine; Humans; Middle Aged; Neoplasm Recurrence, Local

2000

Other Studies

2 other study(ies) available for o(6)-benzylguanine and 8-hydroxyguanine

Article	Year
Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate. Cancer research, 1995, Oct-15, Volume: 55, Issue:20 Topics: Animals; DNA Repair; Enzyme Inhibitors; Guanine; Leukocytes, Mononuclear; Macaca mulatta; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors	1995
Debenzylation of O(6)-benzyl-8-oxoguanine in human liver: implications for O(6)-benzylguanine metabolism. Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6 Topics: Cytochrome P-450 CYP1A2; DNA, Complementary; Guanine; Humans; Isoenzymes; Liver	2001

Article

Year

Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate.

Cancer research, 1995, Oct-15, Volume: 55, Issue:20

Topics: Animals; DNA Repair; Enzyme Inhibitors; Guanine; Leukocytes, Mononuclear; Macaca mulatta; Male; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Time Factors

1995

Debenzylation of O(6)-benzyl-8-oxoguanine in human liver: implications for O(6)-benzylguanine metabolism.

Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

Topics: Cytochrome P-450 CYP1A2; DNA, Complementary; Guanine; Humans; Isoenzymes; Liver

2001