nystatin-a1 has been researched along with microcystin* in 1 studies
1 other study(ies) available for nystatin-a1 and microcystin
| Article | Year |
|---|---|
Inhibition of hormone-stimulated inositol phosphate production and disruption of cytoskeletal structure. Effects of okadaic acid, microcystin, chlorpromazine, W7 and nystatin.
Inhibition of protein phosphatases 2A and 1 by okadaic acid and microcystin leads to cytoskeletal disruption and formation of plasma membrane blebs (blebbing) in hepatocytes. This phenomenon is associated to a marked inhibition of receptor-mediated and G-protein-mediated phosphoinositide turnover in rat hepatocytes. Other cytoskeletal-disrupting drugs such as chlorpromazine, W7 and nystatin mimic the effect of these protein phosphatase inhibitors on phosphoinositide metabolism and blebbing. Our data suggest that the coupling between G-protein and phospholipase C might be altered by cytoskeletal disruption. Topics: Animals; Antifungal Agents; Cell Culture Techniques; Cell Membrane; Chlorpromazine; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Microcystins; Nystatin; Okadaic Acid; Peptides, Cyclic; Rats; Sulfonamides; Vasodilator Agents | 1994 |