nystatin-a1 and boric-acid

Strain differentiation of 66 clinical isolates of Candida albicans obtained from healthy dentate and complete denture wearers was performed. Resistogram method based on differences in the resistance of C. albicans isolates to sodium selenite, boric acid, cetrimide, sodium periodate and silver nitrate was used for strain differentiation. Of the 32 potential strains that can be distinguished, 14 different resistogram strains of C. albicans were found among the 66 isolates tested. Strain-C--was the most predominant (24.3% of total isolates), while strain A-CDE was the least predominant (1.5%). The results showed no particular association of certain strains with Candida infections in complete denture wearers. Sensitivity to antifungal agents showed that isolates from different strains were most sensitive to amphotericin B and nystatin and least sensitive to miconazole.

Topics: Amphotericin B; Antifungal Agents; Boric Acids; Candida albicans; Candidiasis, Oral; Cetrimonium; Cetrimonium Compounds; Denture, Complete; Drug Resistance, Microbial; Humans; Miconazole; Microbial Sensitivity Tests; Nystatin; Periodic Acid; Silver Nitrate; Sodium Selenite; Stomatitis, Denture

The antifungal treatment of recurrent vulvo-vaginal candidosis is described. Factors which predispose to the condition are discussed and details of their investigation and management mentioned. The problem of reinfection, both from a sexual contact and from the bowel is reviewed, and the general features of management considered.

Topics: Adrenal Cortex Hormones; Boric Acids; Candidiasis, Vulvovaginal; Chronic Disease; Clotrimazole; Contraceptives, Oral; Diabetes Complications; Female; Humans; Menstrual Cycle; Miconazole; Nystatin; Patient Compliance; Rectum; Sexual Behavior; Suppositories; Thyroid Function Tests; Vagina

Topics: Boric Acids; Candidiasis, Vulvovaginal; Female; Humans; Nystatin; Powders