Page last updated: 2024-09-05
nutlin 3 and nutlin 2
nutlin 3 has been researched along with nutlin 2 in 1 studies
Compound Research Comparison
| Studies (nutlin 3) | Trials (nutlin 3) | Recent Studies (post-2010) (nutlin 3) | Studies (nutlin 2) | Trials (nutlin 2) | Recent Studies (post-2010) (nutlin 2) |
|---|---|---|---|---|---|
| 12 | 0 | 10 | 6 | 0 | 5 |
Protein Interaction Comparison
| Protein | Taxonomy | nutlin 3 (IC50) | nutlin 2 (IC50) |
|---|---|---|---|
| Cellular tumor antigen p53 | Homo sapiens (human) | 0.14 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.14 |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Aonuma, M; Fukutake, S; Ikeda, M; Kawato, H; Kitagawa, M; Miyazaki, M; Naito, H; Seki, T; Soga, T | 1 |
Other Studies
1 other study(ies) available for nutlin 3 and nutlin 2
| Article | Year |
|---|---|
Discovery of novel dihydroimidazothiazole derivatives as p53-MDM2 protein-protein interaction inhibitors: synthesis, biological evaluation and structure-activity relationships.
Topics: Drug Design; Humans; Imidazoles; Neoplasms; Protein Interaction Maps; Proto-Oncogene Proteins c-mdm2; Thiazoles; Tumor Suppressor Protein p53 | 2012 |