Page last updated: 2024-09-05
nutlin 3 and MI-63
nutlin 3 has been researched along with MI-63 in 1 studies
Compound Research Comparison
| Studies (nutlin 3) | Trials (nutlin 3) | Recent Studies (post-2010) (nutlin 3) | Studies (MI-63) | Trials (MI-63) | Recent Studies (post-2010) (MI-63) |
|---|---|---|---|---|---|
| 12 | 0 | 10 | 5 | 0 | 3 |
Protein Interaction Comparison
| Protein | Taxonomy | nutlin 3 (IC50) | MI-63 (IC50) |
|---|---|---|---|
| Cellular tumor antigen p53 | Homo sapiens (human) | 0.015 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.0846 |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ding, K; Gao, W; Krajewski, K; Lu, Y; Nikolovska-Coleska, Z; Qin, D; Qiu, S; Roller, PP; Shangary, S; Stuckey, J; Wang, G; Wang, S | 1 |
Other Studies
1 other study(ies) available for nutlin 3 and MI-63
| Article | Year |
|---|---|
Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Indoles; Models, Molecular; Protein Binding; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2006 |