Compounds > nu2058

nu2058 and o(6)-benzylguanine

nu2058 has been researched along with o(6)-benzylguanine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; Golding, BT; Griffin, RJ; Kanugula, S; Lembicz, NK; Newell, DR; Pegg, AE1
Arris, CE; Bentley, J; Boyle, FT; Curtin, NJ; Davies, TG; Endicott, JA; Gibson, AE; Golding, BT; Grant, S; Griffin, RJ; Jewsbury, P; Johnson, LN; Mesguiche, V; Newell, DR; Noble, ME; Tucker, JA; Whitfield, HJ1
Caflisch, A; Dey, F; Huang, D; Kolb, P1
Furuya, T; Ichijo, H; Kojima, H; Nagano, T; Okabe, T; Okamoto, M; Saito, N; Takeda, K1
Pathak, AK; Pathak, V; Reynolds, RC; Seitz, LE; Suling, WJ1

Other Studies

5 other study(ies) available for nu2058 and o(6)-benzylguanine

ArticleYear
Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O(6)-(1-cyclopentenylmethyl)guanine.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Cell Extracts; Dacarbazine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Guanine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Tumor Cells, Cultured

2000
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
    Journal of medicinal chemistry, 2002, Aug-01, Volume: 45, Issue:16

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Division; Crystallography, X-Ray; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Guanine; Humans; Models, Molecular; Protein Serine-Threonine Kinases; Ribose; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Humans; Models, Molecular; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Quantitative Structure-Activity Relationship; Static Electricity; Thermodynamics

2008
Identification of novel ASK1 inhibitors using virtual screening.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Chromatography, High Pressure Liquid; Ligands; MAP Kinase Kinase Kinase 5; Mass Spectrometry; Models, Molecular; Protein Kinase Inhibitors

2011
6-Oxo and 6-thio purine analogs as antimycobacterial agents.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Purines; Sulfhydryl Compounds; Tuberculosis; Vero Cells

2013