Compounds > nsc 664704

nsc 664704 and chir 99021

nsc 664704 has been researched along with chir 99021 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Flajolet, M; Greengard, P; Meijer, L1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Austen, M; Burk, U; Dohrmann, C; Ferandin, Y; Geese, M; Kegel, S; Kunick, C; Lemcke, T; Lomow, A; Lozach, O; Meijer, L; Mussmann, R; Stukenbrock, H1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Boyce, RS; Brown, SP; Bussiere, DE; Fang, E; Goff, D; Harrison, SD; Jansen, JM; Johnson, KW; Le, VP; Levine, BH; Ng, SC; Ni, ZJ; Nuss, JM; Pfister, KB; Ramurthy, S; Renhowe, PA; Ring, DB; Shafer, CM; Shu, W; Subramanian, S; Wagman, AS; Zhou, XA1
Feng, F; Jiang, X; Liu, X; Sun, H; Wang, Y; Xu, J; Xu, K; Zhou, J1
Baharvand, H; Eftekhari-Yazdi, P; Gourabi, H; Hassani, SN; Masoudi, NS; Nokhbatolfoghahai, M; Pakzad, M; Rezazadeh Valojerdi, M; Taei, A1
Ek, F; Lang, S; Olsson, R; Parmar, M; Pfisterer, U; Soneji, S1
Amador, A; Bello, SA; Cuesta, JM; Díaz-Díaz, LM; García-Arrarás, JE; Grillo-Alvarado, V; Reyes-Rivera, J; Rodríguez, N; Rodríguez-Flores, EJ; Toledo-Román, EJ; Torres-Gutiérrez, V; Vázquez-Figueroa, LD1

Reviews

1 review(s) available for nsc 664704 and chir 99021

ArticleYear
Pharmacological inhibitors of glycogen synthase kinase 3.
    Trends in pharmacological sciences, 2004, Volume: 25, Issue:9

    Topics: Animals; Cell Differentiation; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Neoplasms; Nervous System Diseases; Parasitic Diseases; Signal Transduction; Stem Cells; Structure-Activity Relationship

2004

Other Studies

8 other study(ies) available for nsc 664704 and chir 99021

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
9-cyano-1-azapaullone (cazpaullone), a glycogen synthase kinase-3 (GSK-3) inhibitor activating pancreatic beta cell protection and replication.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Animals; Azepines; Binding Sites; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Indoles; Insulin-Secreting Cells; Models, Molecular; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship

2008
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3.
    Journal of medicinal chemistry, 2017, 10-26, Volume: 60, Issue:20

    Topics: Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetulus; Crystallography, X-Ray; Enzyme Inhibitors; Glycogen Synthase Kinases; Humans; Hypoglycemic Agents; Mass Spectrometry; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Rats; Structure-Activity Relationship

2017
PROTACs suppression of GSK-3β, a crucial kinase in neurodegenerative diseases.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Enzyme Inhibitors; Glycogen Synthase Kinase 3 beta; HT29 Cells; Humans; Models, Molecular; Neurodegenerative Diseases; PC12 Cells; Proteolysis; Rats; Small Molecule Libraries

2021
Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase β and Rho-associated kinase signaling.
    Human reproduction (Oxford, England), 2013, Volume: 28, Issue:10

    Topics: Amides; Benzazepines; Blastomeres; Cell Differentiation; Cell Line; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Embryonic Stem Cells; Fibroblast Growth Factor 2; Glycogen Synthase Kinases; Humans; Indoles; Karyotyping; Pyridines; Pyrimidines; rho-Associated Kinases; Signal Transduction

2013
Small molecules increase direct neural conversion of human fibroblasts.
    Scientific reports, 2016, 12-05, Volume: 6

    Topics: Anilides; Benzazepines; Cell Line; Cellular Reprogramming; Cyclic AMP; Dinoprostone; Fetus; Fibroblasts; Gene Expression Regulation; Genetic Vectors; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lentivirus; Nerve Tissue Proteins; Neurons; Pyridines; Pyrimidines; Resveratrol; Small Molecule Libraries; Stilbenes; Transcription Factors; Transduction, Genetic

2016
Insights into intestinal regeneration signaling mechanisms.
    Developmental biology, 2020, 02-01, Volume: 458, Issue:1

    Topics: Animals; Benzazepines; Benzeneacetamides; beta Catenin; Cell Dedifferentiation; Cell Nucleus; Cell Proliferation; Glycogen Synthase Kinase 3; Holothuria; Indoles; Intestines; Lithium Chloride; Muscle Cells; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Pyrimidines; Pyrroles; Regeneration; Thiazolidinediones; Wnt Signaling Pathway

2020