Compounds > nsc 615985

nsc 615985 and carboxin

nsc 615985 has been researched along with carboxin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (92.31)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bader, JP; Boyd, MR; Harrison, WA; McMahon, JB; Midelfort, CF; Narayanan, VL; Pierce, JB; Schultz, RJ; Stinson, SF; Weislow, OS1
Dmitrienko, GI; Fletcher, RS; Mithani, S; Parniak, MA; Syed, K1
Balzarini, J; Camarasa, MJ; De Clercq, E; Karlsson, A; Pérez-Pérez, MJ; San-Félix, A; Vélazquez, S1
Arion, D; Borkow, G; Dmitrienko, GI; Fletcher, RS; Parniak, MA; Wainberg, MA1
Balzarini, J; Brouwer, WG; De Clercq, E; Felauer, EE; Karlsson, A1
Bader, JP; Boyd, MR; Brouwer, WG; Buckheit, RW; Currens, MJ; Felauer, EE; Gulakowski, RJ; McMahon, JB; Narayanan, VL; Russell, JD; Schultz, RJ; Shoemaker, RH; Stinson, SF; Vistica, DT1
Brouwer, WG; Buckheit, RW; Dao, DC; Fliakas-Boltz, V; Harrison, WA; Kinjerski, TL; Pallansch, LA; Russell, JD; Schultz, RJ; Stup, TL1
Buckheit, RW; Kinjerski, TL1
Barnard, J; Belmonte, A; Borkow, G; Nguyen, TM; Parniak, MA; Wainberg, MA1
Balzarini, J; De Clercq, E; Esnouf, RM; Schwartz, E; Stuart, DI1
Chadwick, M; Covey, JM; Ferrala, NF; McComish, MF; Nomeir, AA; Silveira, D1
Balzarini, J; Esnouf, RM; Hopkins, AL; Ren, J; Stammers, DK; Stuart, DI; Warren, J1
Hahn, HG; Lee, CK; Rhee, HK; Whang, KJ1

Other Studies

13 other study(ies) available for nsc 615985 and carboxin

ArticleYear
Oxathiin carboxanilide, a potent inhibitor of human immunodeficiency virus reproduction.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Aug-01, Volume: 88, Issue:15

    Topics: Animals; Antiviral Agents; Carboxin; CD4 Antigens; Cell Line; Cricetinae; Drug Evaluation, Preclinical; HIV Protease Inhibitors; HIV-1; Humans; Reverse Transcriptase Inhibitors; Virus Replication

1991
Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme.
    Biochemistry, 1995, Apr-04, Volume: 34, Issue:13

    Topics: Affinity Labels; Benzodiazepinones; Binding Sites; Binding, Competitive; Carboxin; DNA Primers; HIV Reverse Transcriptase; HIV-1; Kinetics; Nevirapine; Photochemistry; Pyridines; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides; Ultraviolet Rays

1995
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives).
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-06, Volume: 92, Issue:12

    Topics: Antiviral Agents; Base Sequence; Carboxin; Cell Line; Delavirdine; DNA Primers; Drug Antagonism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Molecular Sequence Data; Mutation; Piperazines; Reverse Transcriptase Inhibitors; Spiro Compounds; Thymidine

1995
Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds.
    Biochemistry, 1995, Aug-15, Volume: 34, Issue:32

    Topics: Antiviral Agents; Base Sequence; Benzoates; Carboxin; Cell Line; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides; Reverse Transcriptase Inhibitors; Templates, Genetic; Thiocarbamates; Virus Replication

1995
Activity of various thiocarboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains.
    Antiviral research, 1995, Volume: 27, Issue:3

    Topics: Antiviral Agents; Benzoates; Carboxin; Cell Line; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thiocarbamates

1995
Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Animals; Antiviral Agents; Benzoates; Biological Availability; Carboxin; Cricetinae; DNA Mutational Analysis; DNA, Viral; Drug Administration Schedule; Drug Resistance, Microbial; Drug Stability; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Microbial Sensitivity Tests; Rats; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thiocarbamates; Zidovudine

1996
Structure-activity and cross-resistance evaluations of a series of human immunodeficiency virus type-1-specific compounds related to oxathiin carboxanilide.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:12

    Topics: Antiviral Agents; Carboxin; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis, Site-Directed; Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship

1995
The role of genotypic heterogeneity in wild type virus populations on the selection of nonnucleoside reverse transcriptase inhibitor-resistant viruses.
    Antiviral research, 1997, Volume: 33, Issue:2

    Topics: Anti-HIV Agents; Carboxin; Cell Line; Drug Resistance, Microbial; Genetic Heterogeneity; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Selection, Genetic

1997
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of virology, 1997, Volume: 71, Issue:4

    Topics: Anilides; Anti-HIV Agents; Carboxin; Cell Line, Transformed; Cells, Cultured; Furans; HIV Core Protein p24; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Thioamides; Tumor Cells, Cultured

1997
Models which explain the inhibition of reverse transcriptase by HIV-1-specific (thio)carboxanilide derivatives.
    Biochemical and biophysical research communications, 1997, May-19, Volume: 234, Issue:2

    Topics: Anilides; Benzodiazepines; Carboxin; Drug Design; Furans; HIV Reverse Transcriptase; HIV-1; Imidazoles; Models, Molecular; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thioamides

1997
Liquid chromatographic analysis in mouse, dog and human plasma; stability, absorption, metabolism and pharmacokinetics of the anti-HIV agent 2-chloro-5-(2-methyl-5,6-dihydro-1,4-oxathiin-3-yl carboxamido) isopropylbenzoate (NSC 615985, UC84).
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:1

    Topics: Animals; Anti-HIV Agents; Carboxin; Chromatography, High Pressure Liquid; Dogs; Humans; Male; Mice; Reference Standards; Reproducibility of Results; Reverse Transcriptase Inhibitors; Spectrophotometry, Ultraviolet

1998
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
    Biochemistry, 1998, Oct-13, Volume: 37, Issue:41

    Topics: Anilides; Anti-HIV Agents; Benzoates; Binding Sites; Carboxin; Computer Simulation; Crystallization; Crystallography, X-Ray; Furans; HIV Reverse Transcriptase; Humans; Models, Molecular; Protein Conformation; Reverse Transcriptase Inhibitors; Stereoisomerism; Thioamides; Thiocarbamates

1998
Designs and syntheses of oxathiin carboxanilide analogues and their antiviral activities.
    Archives of pharmacal research, 2000, Volume: 23, Issue:4

    Topics: Antiviral Agents; Carboxin; HIV-1; Poliovirus; Structure-Activity Relationship

2000