nsc-614846 and aristeromycin

nsc-614846 has been researched along with aristeromycin* in 2 studies

Other Studies

2 other study(ies) available for nsc-614846 and aristeromycin

Article	Year
Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. Organic letters, 2011, Jun-17, Volume: 13, Issue:12 Acetoxy Meldrum's acid can serve as a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. The reaction of this nucleophile with various meso and racemic electrophiles afforded alkylated products in high yields and enantiopurities. These enantioenriched products are versatile intermediates that can be further functionalized using nitrogen- and oxygen-centered nucleophiles, affording versatile scaffolds for the synthesis of nucleoside analogues. These scaffolds were used to complete formal syntheses of the anti-HIV drugs carbovir, abacavir, and the antibiotic aristeromycin. Topics: Adenosine; Alkylation; Allyl Compounds; Anions; Anti-HIV Agents; Catalysis; Combinatorial Chemistry Techniques; Dideoxynucleosides; Dioxanes; Molecular Structure; Palladium; Stereoisomerism	2011
A novel, one-pot ring expansion of cyclobutanones. Syntheses of carbovir and aristeromycin. The Journal of organic chemistry, 2000, Mar-24, Volume: 65, Issue:6 A novel, one-pot ring-expansion procedure was developed using Me3S(O)I, NaH, and Sc(OTf)3. The scope and limitations were briefly examined, and a tentative mechanism was proposed. Application of the methodology to known cyclobutanone 1 provided the corresponding cyclopentanone, which was successfully advanced to (+)-carbovir and (+)-aristeromycin. Topics: Adenosine; Anti-HIV Agents; Butanones; Dideoxynucleosides; Stereoisomerism	2000

Article

Year

Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation.

Organic letters, 2011, Jun-17, Volume: 13, Issue:12

Acetoxy Meldrum's acid can serve as a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. The reaction of this nucleophile with various meso and racemic electrophiles afforded alkylated products in high yields and enantiopurities. These enantioenriched products are versatile intermediates that can be further functionalized using nitrogen- and oxygen-centered nucleophiles, affording versatile scaffolds for the synthesis of nucleoside analogues. These scaffolds were used to complete formal syntheses of the anti-HIV drugs carbovir, abacavir, and the antibiotic aristeromycin.

Topics: Adenosine; Alkylation; Allyl Compounds; Anions; Anti-HIV Agents; Catalysis; Combinatorial Chemistry Techniques; Dideoxynucleosides; Dioxanes; Molecular Structure; Palladium; Stereoisomerism

2011

A novel, one-pot ring expansion of cyclobutanones. Syntheses of carbovir and aristeromycin.

The Journal of organic chemistry, 2000, Mar-24, Volume: 65, Issue:6

A novel, one-pot ring-expansion procedure was developed using Me3S(O)I, NaH, and Sc(OTf)3. The scope and limitations were briefly examined, and a tentative mechanism was proposed. Application of the methodology to known cyclobutanone 1 provided the corresponding cyclopentanone, which was successfully advanced to (+)-carbovir and (+)-aristeromycin.

Topics: Adenosine; Anti-HIV Agents; Butanones; Dideoxynucleosides; Stereoisomerism

2000