nsc-290205 and phenacid

nsc-290205 has been researched along with phenacid* in 1 studies

Other Studies

1 other study(ies) available for nsc-290205 and phenacid

Article	Year
Interaction of homo-aza-steroidal ester of [p-[bis-(2-chloroethyl) amino]phenyl]acetic acid (ASE) with DNA of Ehrlich ascites tumor cells. FEBS letters, 1983, Mar-07, Volume: 153, Issue:1 A cytostatic, homo-aza-steroidal ester of [p-[bis-(2-chloroethyl) amino]phenyl]acetic acid (ASE) was reduced with NaB3H4 and [3H]ASE-treated DNA prepared in vitro. We found that: (1) ASE reacts preferentially with purines; (2) ASE decreases the thermal stability of the double helix upon binding to DNA; (3) [3H]ASE binding sites are clustered along the DNA molecules; (4) ASE binding sites probably represent oligo- or polypurine sequences. Topics: Animals; Antineoplastic Agents; Azasteroids; Borohydrides; Carcinoma, Ehrlich Tumor; DNA; Drug Stability; Hot Temperature; Kinetics; Mice; Nitrogen Mustard Compounds; Nucleic Acid Conformation; Oxidation-Reduction; Purines	1983

Article

Year

Interaction of homo-aza-steroidal ester of [p-[bis-(2-chloroethyl) amino]phenyl]acetic acid (ASE) with DNA of Ehrlich ascites tumor cells.

FEBS letters, 1983, Mar-07, Volume: 153, Issue:1

A cytostatic, homo-aza-steroidal ester of [p-[bis-(2-chloroethyl) amino]phenyl]acetic acid (ASE) was reduced with NaB3H4 and [3H]ASE-treated DNA prepared in vitro. We found that: (1) ASE reacts preferentially with purines; (2) ASE decreases the thermal stability of the double helix upon binding to DNA; (3) [3H]ASE binding sites are clustered along the DNA molecules; (4) ASE binding sites probably represent oligo- or polypurine sequences.

Topics: Animals; Antineoplastic Agents; Azasteroids; Borohydrides; Carcinoma, Ehrlich Tumor; DNA; Drug Stability; Hot Temperature; Kinetics; Mice; Nitrogen Mustard Compounds; Nucleic Acid Conformation; Oxidation-Reduction; Purines

1983