Compounds > nsc 224070
Page last updated: 2024-09-03

nsc 224070 and diaziquone

nsc 224070 has been researched along with diaziquone in 9 studies

Compound Research Comparison

Studies
(nsc 224070)		Trials
(nsc 224070)		Recent Studies (post-2010)
(nsc 224070)		Studies
(diaziquone)		Trials
(diaziquone)		Recent Studies (post-2010) (diaziquone)
1301204226

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's7 (77.78)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Boer, M; Driebergen, RJ; Hilbers, HW; Holthuis, JJ; Janssen, LH; Moret, EE; Reinhoudt, DN; Tollenaere, JP; Verboom, W1
Butler, J; Hargreaves, RH; Hartley, JA; Mayalarp, SP; McAdam, SR; O'Hare, CC1
Butler, J; Gibson, NW; Hartley, JA; Ross, D; Siegel, D1
Berardini, M; Butler, J; Gibson, NW; Hartley, JA; Hoey, BM; Ponti, M; Thompson, AS; Thurston, DE1
Butler, J; Dzielendziak, A; Hoey, BM; Lea, JS; Ward, TH1
Butler, J; Garner, HJ; Hoey, BM; Lea, JS; Ward, TH1
Butler, J; Hoey, BM; Lea, JS1
Butler, J; Haran, MS; Howard, TD; Ward, TH; Watson, AJ; Whittaker, D1
Butler, J; Richards, JT; Shahbakhti, H; Ward, TH1

Other Studies

9 other study(ies) available for nsc 224070 and diaziquone

ArticleYear
In vivo activity and hydrophobicity of cytostatic aziridinyl quinones.
    Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Leukemia L1210; Melanoma, Experimental; Mice

1996
Cross-linking and sequence specific alkylation of DNA by aziridinyl quinones. 2. Structure requirements for sequence selectivity.
    Journal of medicinal chemistry, 1997, Jan-31, Volume: 40, Issue:3

    Topics: Alkylation; Antineoplastic Agents, Alkylating; Aziridines; Benzoquinones; Cell Survival; Computer Simulation; Cross-Linking Reagents; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Nucleic Acid Conformation; Tumor Cells, Cultured

1997
Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Molecular pharmacology, 1992, Volume: 42, Issue:3

    Topics: Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Colonic Neoplasms; DNA Damage; Humans; Liver; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Rats; Tumor Cells, Cultured

1992
DNA cross-linking and sequence selectivity of aziridinylbenzoquinones: a unique reaction at 5'-GC-3' sequences with 2,5-diaziridinyl-1,4-benzoquinone upon reduction.
    Biochemistry, 1991, Dec-17, Volume: 30, Issue:50

    Topics: Antineoplastic Agents; Autoradiography; Aziridines; Base Sequence; Benzoquinones; Cross-Linking Reagents; DNA; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Oxidation-Reduction; Uracil Mustard

1991
Contrasting cytotoxic mechanisms of similar antitumour diaziridinylbenzoquinones.
    Free radical research communications, 1990, Volume: 8, Issue:4-6

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Cell Survival; Chromatography, High Pressure Liquid; DNA; Drug Stability; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction

1990
The lack of correlation between toxicity and free radical formation of two diaziridinyl benzoquinones.
    Biochemical pharmacology, 1988, May-15, Volume: 37, Issue:10

    Topics: Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Cell Survival; Free Radicals; Quinones; Superoxides

1988
The reduction of anti-tumour diaziridinyl benzoquinones.
    Biochimica et biophysica acta, 1987, Aug-13, Volume: 925, Issue:2

    Topics: Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Cross-Linking Reagents; Electron Spin Resonance Spectroscopy; Free Radicals; Oxidation-Reduction; Quinones; Solubility; Spectrum Analysis

1987
Cross-resistance studies on two K562 sublines resistant to diaziridinylbenzoquinones.
    Biochemical pharmacology, 1995, Aug-08, Volume: 50, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Aziridines; Benzoquinones; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Glutathione; Humans; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Superoxide Dismutase

1995
Comet assay studies on the activation of two diaziridinylbenzoquinones in K562 cells.
    Biochemical pharmacology, 1997, Apr-25, Volume: 53, Issue:8

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Cross-Linking Reagents; DNA Damage; DNA Repair; Drug Resistance; Electrophoresis, Agar Gel; Humans; Tumor Cells, Cultured

1997