Page last updated: 2024-09-04

nsc 181928 and nocodazole

nsc 181928 has been researched along with nocodazole in 4 studies

Compound Research Comparison

Studies
(nsc 181928)
Trials
(nsc 181928)
Recent Studies (post-2010)
(nsc 181928)
Studies
(nocodazole)
Trials
(nocodazole)
Recent Studies (post-2010) (nocodazole)
9003,0780655

Protein Interaction Comparison

ProteinTaxonomynsc 181928 (IC50)nocodazole (IC50)
Chain A, Glutathione-requiring prostaglandin D synthaseHomo sapiens (human)65
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)0.8334
Tyrosine-protein kinase ABL1Homo sapiens (human)0.64
Tubulin alpha-1A chainSus scrofa (pig)1.3775
Tubulin beta chainSus scrofa (pig)0.76
Tubulin beta-4A chainHomo sapiens (human)1.2975
Tubulin beta chainHomo sapiens (human)1.2975
Tubulin alpha-3C chainHomo sapiens (human)1.2975
Adenosine receptor A2aHomo sapiens (human)7.509
Tubulin alpha-1B chainHomo sapiens (human)1.2975
Tubulin alpha-4A chainHomo sapiens (human)1.2975
Tubulin beta-4B chainHomo sapiens (human)1.2975
Sodium-dependent dopamine transporter Homo sapiens (human)6.232
Tubulin beta-3 chainHomo sapiens (human)1.2975
Tubulin beta-2A chainHomo sapiens (human)1.2975
Tubulin beta-8 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainBos taurus (cattle)2.3
Tubulin alpha-3E chainHomo sapiens (human)1.2975
Tubulin alpha-1A chainHomo sapiens (human)1.2975
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)2.3
Tubulin alpha-1C chainHomo sapiens (human)1.2975
Tubulin beta-6 chainHomo sapiens (human)1.2975
Tubulin beta-2B chainHomo sapiens (human)1.2975
Tubulin beta-1 chainHomo sapiens (human)1.2975

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Comber, RN; Elliott, RD; Kussner, CL; Montgomery, JA; Rose, JD; Temple, C; Wheeler, GP1
Chi, DM; Hamel, E; Ho, HH; Shahrik, LK1
Gupta, RS1
Adamson, DJ; Bowdon, BJ; Temple, C; Webster, J; Wheeler, GP1

Other Studies

4 other study(ies) available for nsc 181928 and nocodazole

ArticleYear
New anticancer agents: synthesis of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines).
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:9

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Leukemia L1210; Leukemia P388; Mice; Mitosis; Pyrazines; Pyridines

1982
Tubulin-dependent hydrolysis of guanosine triphosphate as a screening test to identify new antitubulin compounds with potential as antimitotic agents: application to carbamates of aromatic amines.
    Cancer research, 1989, Mar-15, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Benzimidazoles; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Mitosis; Nocodazole; Pyrazines; Quinazolines; Structure-Activity Relationship; Tubulin Modulators

1989
Cross-resistance of nocodazole-resistant mutants of CHO cells toward other microtubule inhibitors: similar mode of action of benzimidazole carbamate derivatives and NSC 181928 and TN-16.
    Molecular pharmacology, 1986, Volume: 30, Issue:2

    Topics: Animals; Benzimidazoles; Carbamates; Cell Line; Cricetinae; Drug Resistance; Female; Microtubules; Mutation; Nocodazole; Ovary; Podophyllotoxin; Pyrazines; Pyrrolidinones

1986
Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Division; Cell Survival; Colchicine; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nocodazole; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine

1983