npf-etoposide has been researched along with etoposide in 13 studies
| Studies (npf-etoposide) | Trials (npf-etoposide) | Recent Studies (post-2010) (npf-etoposide) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 13 | 0 | 0 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | npf-etoposide (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YC; Hu, H; Lee, KH; Liu, SY; Wang, ZQ | 1 |
| Chen, HX; Cheng, YC; Hu, H; Lee, KH; Wang, ZQ | 1 |
| Chen, HX; Cheng, YC; Guo, X; Lee, KH; Shen, YC; Wang, ZQ; Zhang, YL | 1 |
| Chang, JY; Chen, HX; Cheng, YC; Lee, KH; Wang, ZQ; Zhou, XM | 1 |
| Beers, SA; Chang, JY; Cheng, YC; Han, FS; Kuo, YH; Lee, KH; Li, L; Liu, SY; Mori, M; Wang, ZQ | 1 |
| Bowen, JP; Chang, JY; Cheng, YC; Han, FS; Kuo, YH; Lee, KH; Liu, SY; Schnur, D; Wang, ZQ | 1 |
| Lee, KH; McPhail, AT; Tropsha, A; Zhang, YL | 1 |
| Chen, HX; Cheng, J; Cheng, YC; Guo, X; Lee, KH; Lee, KJ; Wu, SS; Zhou, XM | 1 |
| Cheng, YC; Cho, SJ; Lee, KH; Suffness, M; Tropsha, A | 1 |
| Bastow, KF; Huang, ES; Lee, KH; Tachibana, Y; VanVliet, DS | 1 |
| Feng, J; Golbraikh, A; Lee, KH; Tropsha, A; Xiao, YD; Xiao, Z | 1 |
| Lee, KH | 2 |
2 review(s) available for npf-etoposide and etoposide
| Article | Year |
|---|---|
Current developments in the discovery and design of new drug candidates from plant natural product leads.
Topics: Anti-HIV Agents; Antineoplastic Agents; Biological Factors; Drug Design; Molecular Structure; Plants, Medicinal; Structure-Activity Relationship | 2004 |
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
Topics: Anti-HIV Agents; Biological Factors; Drug Design; Molecular Structure; Pharmaceutical Preparations; Plants, Medicinal | 2010 |
11 other study(ies) available for npf-etoposide and etoposide
| Article | Year |
|---|---|
Antitumor agents. 123. Synthesis and human DNA topoisomerase II inhibitory activity of 2'-chloro derivatives of etoposide and 4 beta-(arylamino)-4'-O-demethylpodophyllotoxins.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; KB Cells; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Succinimides; Topoisomerase II Inhibitors | 1992 |
Antitumor agents. 124. New 4 beta-substituted aniline derivatives of 6,7-O,O-demethylene-4'-O-demethylpodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.
Topics: Aniline Compounds; Antineoplastic Agents; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; KB Cells; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1992 |
Antitumor agents, 130, Novel 4 beta-arylamino derivatives of 3',4'-didemethoxy-3',4'-dioxo-4-deoxypodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
Topics: Antineoplastic Agents, Phytogenic; DNA; DNA Damage; DNA, Neoplasm; Humans; KB Cells; Podophyllotoxin; Topoisomerase II Inhibitors | 1992 |
Antitumor agents. 120. New 4-substituted benzylamine and benzyl ether derivatives of 4'-O-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
Topics: Enzyme Inhibitors; Humans; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1991 |
Antitumor agents. 111. New 4-hydroxylated and 4-halogenated anilino derivatives of 4'-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
Topics: Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Humans; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1990 |
Antitumor agents. 113. New 4 beta-arylamino derivatives of 4'-O-demethylepipodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.
Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Humans; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1990 |
Antitumor agents. 152. In vitro inhibitory activity of etoposide derivative NPF against human tumor cell lines and a study of its conformation by X-ray crystallography, molecular modeling, and NMR spectroscopy.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Etoposide; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Tumor Cells, Cultured | 1994 |
Antitumor agents. 144. New gamma-lactone ring-modified arylamino etoposide analogs as inhibitors of human DNA topoisomerase II.
Topics: Antineoplastic Agents; Cell Line; DNA; Ethers; Etoposide; Humans; Lactones; Topoisomerase II Inhibitors | 1994 |
Antitumor agents. 163. Three-dimensional quantitative structure-activity relationship study of 4'-O-demethylepipodophyllotoxin analogs using the modified CoMFA/q2-GRS approach.
Topics: Antineoplastic Agents; Computer Graphics; DNA; DNA Topoisomerases, Type I; Models, Molecular; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; Podophyllotoxin; Structure-Activity Relationship | 1996 |
Antitumor agents. 207. Design, synthesis, and biological testing of 4beta-anilino-2-fluoro-4'-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chlorocebus aethiops; DNA; Drug Design; Drug Screening Assays, Antitumor; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells | 2001 |
Antitumor agents. 213. Modeling of epipodophyllotoxin derivatives using variable selection k nearest neighbor QSAR method.
Topics: Antineoplastic Agents; Models, Molecular; Podophyllotoxin; Quantitative Structure-Activity Relationship | 2002 |