Compounds > npc 17761
Page last updated: 2024-09-05

npc 17761 and bradykinin

npc 17761 has been researched along with bradykinin in 5 studies

Compound Research Comparison

Studies
(npc 17761)		Trials
(npc 17761)		Recent Studies (post-2010)
(npc 17761)		Studies
(bradykinin)		Trials
(bradykinin)		Recent Studies (post-2010) (bradykinin)
50014,1953551,520

Protein Interaction Comparison

ProteinTaxonomynpc 17761 (IC50)bradykinin (IC50)
B2 bradykinin receptorHomo sapiens (human)0.0018

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amrani, Y; Da Silva, A; Landry, Y; Trifilieff, A1
Abraham, WM; Burch, R; Forteza, R; Lauredo, IT1
Amrani, Y; Gies, JP; Landry, Y; Trifilieff, A1
Kyle, DJ; Lowe, VC; Noronha-Blob, L; Otterbein, L1
Cabrini, DA; Calixto, JB; Kyle, DJ1

Other Studies

5 other study(ies) available for npc 17761 and bradykinin

ArticleYear
Involvement of B2 receptors in the bradykinin-induced relaxation of guinea-pig isolated trachea.
    British journal of pharmacology, 1995, Volume: 114, Issue:1

    Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Melitten; Receptors, Adrenergic, beta-2; Relaxation; Thiorphan; Trachea

1995
Extracellular metabolites of Pseudomonas aeruginosa produce bronchoconstriction by different mechanisms.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:3 Pt 1

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Chlorpheniramine; Constriction, Pathologic; Drug Evaluation, Preclinical; Endotoxins; Female; Inflammation; Kinins; Nedocromil; Phenazines; Premedication; Pseudomonas aeruginosa; Pyocyanine; Sheep

1994
Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Animals; Binding, Competitive; Bradykinin; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Kinins; Muscle Contraction; Muscle, Smooth; Oligopeptides; Receptors, Bradykinin; Trachea

1993
Additive effects of a bradykinin antagonist, NPC 17761, and a leumedin, NPC 15669, on survival in animal models of sepsis.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Disease Models, Animal; Drug Synergism; Endotoxins; Leucine; Male; Mice; Molecular Sequence Data; Peritonitis; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Rate

1993
A pharmacological analysis of receptor subtypes and the mechanisms mediating the biphasic response induced by kinins in the rat stomach fundus in vitro.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Animals; Bradykinin; Calcium; Gastric Fundus; In Vitro Techniques; Lipopolysaccharides; Male; Rats; Rats, Wistar; Receptors, Bradykinin

1996