npc 12626 has been researched along with n-methylaspartate in 16 studies
| Studies (npc 12626) | Trials (npc 12626) | Recent Studies (post-2010) (npc 12626) | Studies (n-methylaspartate) | Trials (n-methylaspartate) | Recent Studies (post-2010) (n-methylaspartate) |
|---|---|---|---|---|---|
| 55 | 0 | 0 | 10,408 | 59 | 1,902 |
| Protein | Taxonomy | npc 12626 (IC50) | n-methylaspartate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.175 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 12 (75.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conti, L; Ellenberger, SR; Ellenberger, WP; Ferkany, JW; Guzewska, ME; Hudkins, R; Kyle, DJ; Narayanan, BA; Patch, R; Rzeszotarski, WJ | 1 |
| Heikkila, RE; Riordan, DE; Sonsalla, PK | 1 |
| Gold, PE; Walker, DL | 1 |
| Abreu, M; Ferkany, J; French, ED; Levenson, S | 1 |
| Balster, RL; Jortani, SA; Mansbach, RS; Willetts, J | 1 |
| Mansbach, RS | 1 |
| Ferkany, JW; Kyle, DJ; Rzeszotarski, WJ | 1 |
| Borosky, S; Ellenberger, SR; Ferkany, JW; Guzewska, ME; Jones, SM; Kyle, DJ; Rzeszotarski, WJ; Sacaan, AI; Snell, LD; Willets, J | 1 |
| Balster, RL; Willetts, J | 1 |
| Balster, RL; Bobelis, DJ; Willetts, J | 1 |
| Austin, KB; Hetherington, PA; Shapiro, ML | 1 |
| Ferkany, J; Kolesnikov, YA; Pasternak, GW | 1 |
| Bednar, DL; Borosky, SA; Ferkany, JW; Hamilton, GS; Huang, Z; Jones, BE; Karbon, EW; Patch, RJ; Willetts, J; Zubrowski, R | 1 |
| Boon, F; Cain, DP; Saucier, D | 1 |
| Balster, RL; Jones, HE; Nicholson, KL | 1 |
| Balster, RL; Wiley, JL | 1 |
1 review(s) available for npc 12626 and n-methylaspartate
| Article | Year |
|---|---|
NPC 12626, a novel, competitive NMDA antagonist: pharmacological and toxicological profile.
Topics: Amino Acids; Animals; Binding, Competitive; N-Methylaspartate; Seizures | 1990 |
15 other study(ies) available for npc 12626 and n-methylaspartate
| Article | Year |
|---|---|
Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Electroshock; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship | 1992 |
Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
Topics: Amino Acids; Animals; Corpus Striatum; Dizocilpine Maleate; Male; Methamphetamine; Mice; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 1991 |
Effects of the novel NMDA antagonist, NPC 12626, on long-term potentiation, learning and memory.
Topics: Amino Acids; Animals; Avoidance Learning; Behavior, Animal; Evoked Potentials, Somatosensory; Hippocampus; Learning; Male; Memory; Mice; Mice, Inbred ICR; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses | 1991 |
Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: an electrophysiological and behavioral comparison to phencyclidine.
Topics: Amino Acids; Amphetamine; Animals; Behavior, Animal; Dopamine; Electrophysiology; Limbic System; Male; Mesencephalon; Motor Activity; N-Methylaspartate; Neurons; Nucleus Accumbens; Oxidopamine; Phencyclidine; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
NMDA antagonists: lack of antipunishment effect in squirrel monkeys.
Topics: Amino Acids; Animals; Conditioning, Operant; Isoflurophate; Male; Midazolam; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Punishment; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Saimiri | 1991 |
Effects of NMDA receptor ligands on sensorimotor gating in the rat.
Topics: Acoustic Stimulation; Amino Acids; Animals; Dizocilpine Maleate; Ligands; Male; N-Methylaspartate; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Startle | 1991 |
Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; Brain Ischemia; Cerebral Ventricles; Corpus Striatum; Electric Conductivity; Female; Gerbillinae; In Vitro Techniques; Male; Membranes; N-Methylaspartate; Oocytes; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Xenopus | 1989 |
Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline.
Topics: Amino Acids; Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Phenazocine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Drug discrimination based on the competitive N-methyl-D-aspartate antagonist, NPC 12626.
Topics: Amino Acids; Animals; Aspartic Acid; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains | 1989 |
Ipsilateral associational pathway in the dentate gyrus: an excitatory feedback system that supports N-methyl-D-aspartate-dependent long-term potentiation.
Topics: Afferent Pathways; Amino Acids; Animals; Electric Stimulation; Electrodes; Electrophysiology; Evoked Potentials; Feedback; Hippocampus; Long-Term Potentiation; Male; Memory; N-Methylaspartate; Rats; Synapses | 1994 |
Blockade of mu and kappa 1 opioid analgesic tolerance by NPC17742, a novel NMDA antagonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acids; Analgesics; Animals; Drug Tolerance; Mice; Mice, Inbred Strains; Morphine; N-Methylaspartate; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1993 |
Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist.
Topics: Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Binding, Competitive; Brain Ischemia; Electrophysiology; Female; Gerbillinae; Hippocampus; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1993 |
Testing hypotheses of spatial learning: the role of NMDA receptors and NMDA-mediated long-term potentiation.
Topics: Amino Acids; Animals; Behavior, Animal; Discrimination Learning; Electrophysiology; Excitatory Amino Acid Antagonists; Learning; Long-Term Potentiation; Male; Maze Learning; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Space Perception | 1997 |
Evaluation of the reinforcing and discriminative stimulus effects of the N-methyl-D-aspartate competitive antagonist NPC 17742 in rhesus monkeys.
Topics: Amino Acids; Animals; Binding, Competitive; Discrimination, Psychological; Excitatory Amino Acid Antagonists; Female; Macaca mulatta; Male; N-Methylaspartate; Phencyclidine; Reinforcement, Psychology; Self Administration | 1997 |
Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.
Topics: Amino Acids; Animals; Biguanides; Binding Sites; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Riluzole | 2004 |