nov-002 and zileuton

nov-002 has been researched along with zileuton* in 1 studies

Other Studies

1 other study(ies) available for nov-002 and zileuton

ArticleYear
5-Lipoxygenase inhibitor zileuton inhibits Ca(2+)-responses induced by glutoxim and molixan in macrophages.
    Doklady. Biochemistry and biophysics, 2016, Volume: 469, Issue:1

    Using Fura-2AM microfluorimetry, we have shown for the first time that 5-lipoxygenase specific inhibitor antiasthmatic agent zileuton significantly inhibits Ca(2+)-responses induced by glutoxim and molixan in macrophages. The results support 5-lipoxygenase involvement in the effect of glutoxim and molixan on intracellular Ca(2+) concentration in macrophages and indicate the inadvisability of a combined use of drugs glutoxim and molixan and antiasthmatic agent zileuton.

    Topics: Animals; Anti-Asthmatic Agents; Arachidonate 5-Lipoxygenase; Calcium; Calcium Signaling; Cations, Divalent; Cells, Cultured; Cytophotometry; Drug Combinations; Drug Interactions; Fura-2; Hydroxyurea; Inosine; Intracellular Space; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Microscopy, Fluorescence; Oligopeptides; Rats, Wistar

2016