nov-002 has been researched along with rhodamine-phalloidin* in 1 studies
1 other study(ies) available for nov-002 and rhodamine-phalloidin
| Article | Year |
|---|---|
[The involvement of actin cytoskeleton in glutoxim and molixan effect on intracellular Ca(2+)-concentration in macrophages].
Glutoxim and molixan belong to new generation of disulfide-containing drugs with immunomodulatory, hepatoprotective and hemopoetic effect on cells. Using Fura-2AM microfluorimetry, two structurally distinct actin filament disrupters, latrunculin B and cytochalasin D, and calyculin A, which causes actin filaments condensation under plasmalemma, we have shown the involvement of actin cytoskeleton in the intracellular Ca(2+)-concentration increase induced by glutoxim or molixan in rat peritoneal macrophages. Morphological data obtained with the use of rhodamine-phalloidine have demonstrated that glutoxim and molixan cause the actin cytoskeleton reorganization in rat peritoneal macrophages. Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cytochalasin D; Cytoprotection; Drug Combinations; Immunologic Factors; Inosine; Macrophages, Peritoneal; Marine Toxins; Microscopy, Fluorescence; Oligopeptides; Oxazoles; Phalloidine; Rats; Rats, Wistar; Rhodamines; Thiazolidines | 2012 |