nortriptyline and dextromethorphan

nortriptyline has been researched along with dextromethorphan in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (22.22)	18.2507
2000's	4 (44.44)	29.6817
2010's	3 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Commandeur, JN; Funae, Y; Hiroi, T; ter Laak, AM; Venhorst, J; Vermeulen, NP	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Dalvie, D; Loi, CM; Smith, DA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Baettig, D; Baumann, P; Breyer-Pfaff, U; Jonzier-Perey, M; Monney, C; Nill, K; Nusser, E; Pfandl, B	1
Coutts, RT	1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA	1

Reviews

2 review(s) available for nortriptyline and dextromethorphan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping. Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:1 Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic	1994

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.

Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:1

Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic

1994

Other Studies

7 other study(ies) available for nortriptyline and dextromethorphan

Article	Year
Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities. Journal of medicinal chemistry, 2003, Jan-02, Volume: 46, Issue:1 Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Coumarins; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Ligands; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Protein Binding; Quinidine; Quinine; Rabbits; Rats; Sequence Homology, Amino Acid; Sparteine; Species Specificity	2003
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
Enantioselective amitriptyline metabolism in patients phenotyped for two cytochrome P450 isozymes. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:4 Topics: Adult; Amitriptyline; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Isoenzymes; Male; Mephenytoin; Metabolic Clearance Rate; Middle Aged; Nortriptyline; Phenotype; Regression Analysis; Stereoisomerism	1992
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8 Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol	2007