norstictic-acid and depsidone

norstictic-acid has been researched along with depsidone* in 2 studies

Other Studies

2 other study(ies) available for norstictic-acid and depsidone

Article	Year
A new depsidone and antibacterial activities of compounds from Usnea undulata Stirton. Journal of Asian natural products research, 2011, Volume: 13, Issue:12 Usnea undulata Stirton (Usneaaceae) is a fruticose lichen used locally in ethnoveterinary medicine to treat mammary infections in cattle while human beings use it for the treatment of wounds in Eastern Cape, South Africa. Bioactivity-guided fractionation of its extracts led to the isolation and characterization of a new depsidone, 2'-O-methylhypostictic acid (8), together with seven known compounds, i.e. methyl β-orsellinate, norstictic acid, menegazziaic acid, (+) usnic acid, hypoconstictic acid, salazinic acid, and galbinic acid. The structures of the compounds were elucidated on the basis of their spectral analysis including homo- and hetero-nuclear correlation NMR experiments (COSY, NOESY, HMQC, and HMBC) and mass spectra as well as by comparison with available data in the literature. The minimum inhibitory concentrations (MICs) values of the compounds against six bacteria were determined. Compound 8 showed inhibitory activity against Bacillus cereus, Bacillus subtilis, and Staphylococcus epidermidis with MICs of 31, 62.5, 62.5 μg/ml, respectively. (+) Usnic acid was most active against B. subtilis, B. cereus, Staphylococcus aureus, and Escherichia coli with MICs of 8, 8, 31, and 31 μg/ml, respectively, while other compounds exhibited moderate activity. Topics: Animals; Anti-Bacterial Agents; Bacillus cereus; Bacillus subtilis; Benzofurans; Cattle; Depsides; Escherichia coli; Humans; Lactones; Microbial Sensitivity Tests; Salicylates; South Africa; Staphylococcus aureus; Usnea	2011
Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities. Journal of natural products, 2007, Volume: 70, Issue:7 Two new beta-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC50 = 566 and 580 microM, respectively) than quercetin (IC50 = 754 microM). Topics: Antioxidants; Biphenyl Compounds; Depsides; Free Radical Scavengers; Heterocyclic Compounds, 4 or More Rings; Indonesia; Inhibitory Concentration 50; Lactones; Molecular Structure; Oxepins; Picrates; Quercetin; Superoxides; Usnea	2007

Article

Year

A new depsidone and antibacterial activities of compounds from Usnea undulata Stirton.

Journal of Asian natural products research, 2011, Volume: 13, Issue:12

Usnea undulata Stirton (Usneaaceae) is a fruticose lichen used locally in ethnoveterinary medicine to treat mammary infections in cattle while human beings use it for the treatment of wounds in Eastern Cape, South Africa. Bioactivity-guided fractionation of its extracts led to the isolation and characterization of a new depsidone, 2'-O-methylhypostictic acid (8), together with seven known compounds, i.e. methyl β-orsellinate, norstictic acid, menegazziaic acid, (+) usnic acid, hypoconstictic acid, salazinic acid, and galbinic acid. The structures of the compounds were elucidated on the basis of their spectral analysis including homo- and hetero-nuclear correlation NMR experiments (COSY, NOESY, HMQC, and HMBC) and mass spectra as well as by comparison with available data in the literature. The minimum inhibitory concentrations (MICs) values of the compounds against six bacteria were determined. Compound 8 showed inhibitory activity against Bacillus cereus, Bacillus subtilis, and Staphylococcus epidermidis with MICs of 31, 62.5, 62.5 μg/ml, respectively. (+) Usnic acid was most active against B. subtilis, B. cereus, Staphylococcus aureus, and Escherichia coli with MICs of 8, 8, 31, and 31 μg/ml, respectively, while other compounds exhibited moderate activity.

Topics: Animals; Anti-Bacterial Agents; Bacillus cereus; Bacillus subtilis; Benzofurans; Cattle; Depsides; Escherichia coli; Humans; Lactones; Microbial Sensitivity Tests; Salicylates; South Africa; Staphylococcus aureus; Usnea

2011

Stictic acid derivatives from the lichen Usnea articulata and their antioxidant activities.

Journal of natural products, 2007, Volume: 70, Issue:7

Two new beta-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usnea articulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds by comparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds 1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones 4 and 5 showed better superoxide anion scavenging activity (IC50 = 566 and 580 microM, respectively) than quercetin (IC50 = 754 microM).

Topics: Antioxidants; Biphenyl Compounds; Depsides; Free Radical Scavengers; Heterocyclic Compounds, 4 or More Rings; Indonesia; Inhibitory Concentration 50; Lactones; Molecular Structure; Oxepins; Picrates; Quercetin; Superoxides; Usnea

2007