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norpropoxyphene and dextropropoxyphene

norpropoxyphene has been researched along with dextropropoxyphene in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199028 (65.12)18.7374
1990's8 (18.60)18.2507
2000's6 (13.95)29.6817
2010's1 (2.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cleemann, M1
Angelo, HR; Christensen, JM1
McBay, AJ1
Nilsson, LB; Pettersson, KJ1
Bertaux, L; Dellatolas, F; Fournier, PE; Girre, C; Hirschhorn, M; Moreno, M; Ngo, R; Palombo, S1
Lho, D; Park, J; Shin, H1
Angelo, HR; Jacobsen, E; Krantz, T; Lang-Jensen, T; Sørensen, MB; Thisted, B1
Crome, P; Flanagan, RJ; Johnston, A; White, AS1
Aune, H; Bodd, E; Gulliksen, M; Lilleaasen, P; Mørland, J; Olsen, H1
Angelo, HR; Krantz, T; Strøm, J; Sørensen, MB; Thisted, B1
Bodd, E; Gulliksen, M; Mørland, J; Olsen, H1
Bates, TR; Kunka, RL; Ladik, CF; Yong, CL1
Degani, NC; Foltz, RL; Hamilton, CA; Kaplan, HL; Sellers, EM1
Bodd, E; Jensen, J; Mørland, J; Olsen, H; Wethe, G1
Angelo, HR; Kranz, T; Strøm, J; Sørensen, MB; Thisted, B1
Ali, NA; Allen, EM; Graham, DF; Marshall, RW; Richens, A1
Emmerson, JL; Hynes, MD; Nickander, RC; Steinberg, MI; Sullivan, HR1
Flanagan, RJ; Jane, I; Ramsey, JD1
Finkle, BS1
Crome, P; Flanagan, RJ; Gain, R; Ghurye, R1
Buckley, BM; Vale, JA1
Bodd, E; Meyer, T; Mørland, J; Olsen, H1
Kunka, RL; Ladik, CF; Stern, RM; Venkataramanan, R1
Crouch, DJ; Deyman, ME; Finkle, BS; Johnson, JR; Margot, PA1
Colburn, WA; Dayton, HE; Inturrisi, CE; O'Brien, CP; Verebey, K; Woody, GE1
Cochrane, RL; Due, SL; McMahon, RE; Page, JG; Sullivan, HR1
Levy, G; Oguma, T1
Caplan, YH; Finkle, BS; Garriott, JC; Monforte, JR; Shaw, RF; Sonsalla, PK1
Budd, RD; Mathis, DF; Yang, FC1
Baggesen, S; Bechgaard, H1
Daenens, C; Desager, JP; Geubel, AP; Harvengt, C; Horsmans, Y1
Bresson, M; Fornaris, M; Grimaldi, F; Rop, PP; Viala, A1
Franke, M; Kingston, HM; Winek, CL1
Gilly, WF; Horrigan, FT1
Gaillard, Y; Pépin, G1
Daenens, P; Tytgat, J; Ulens, C1
Hajdú, P; Panyi, G; Tytgat, J; Ulens, C1
Lakso, HA; Norström, A1
Backer, RC; Poklis, A; Poklis, JL; Tarnai, LD1
Fullston, SV; Menelaou, A; Somogyi, AA1
Carson, HJ; Eilers, SG1
Crews, B; Latyshev, S; Mikel, C; Pesce, A; West, R1
Di Girolamo, G; Diez, RA; Fernández, N; Keller, GA; Olivera, NM; Quiroga, PN1

Reviews

1 review(s) available for norpropoxyphene and dextropropoxyphene

ArticleYear
Pharmacologic and toxic effects in animals of dextropropoxyphene and its major metabolite norpropoxyphene: a review.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Analgesia; Anesthetics, Local; Animals; Chemical Phenomena; Chemistry; Dextropropoxyphene; Dogs; Drug Tolerance; Guinea Pigs; Heart; Humans; Ileum; In Vitro Techniques; Lethal Dose 50; Mice; Opioid-Related Disorders; Receptors, Opioid

1984

Trials

4 trial(s) available for norpropoxyphene and dextropropoxyphene

ArticleYear
Enhancement of propoxyphene bioavailability by ethanol. Relation to psychomotor and cognitive function in healthy volunteers.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:2

    Topics: Biological Availability; Cognition; Dextropropoxyphene; Double-Blind Method; Drug Synergism; Ethanol; Humans; Male; Psychomotor Performance; Reference Values; Self-Assessment

1991
Cardiovascular function measured by ultrasound Doppler in healthy young men after ingestion of dextropropoxyphene napsylat.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:2

    Topics: Adult; Dextropropoxyphene; Double-Blind Method; Hemodynamics; Humans; Male

1989
Comparison of the effects of therapeutic doses of meptazinol and a dextropropoxyphene/paracetamol mixture alone and in combination with ethanol on ventilatory function and saccadic eye movements.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:6

    Topics: Acetaminophen; Adult; Azepines; Dextropropoxyphene; Double-Blind Method; Ethanol; Eye Movements; Half-Life; Humans; Hypercapnia; Kinetics; Meptazinol; Random Allocation; Respiration; Saccades

1985
D-propoxyphene and norpropoxyphene kinetics after the oral administration of D-propoxyphene: a new approach to liver function?
    Journal of hepatology, 1994, Volume: 21, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amino Acids, Branched-Chain; Ammonia; Bile Acids and Salts; Dextropropoxyphene; Dose-Response Relationship, Drug; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Portacaval Shunt, Surgical

1994

Other Studies

38 other study(ies) available for norpropoxyphene and dextropropoxyphene

ArticleYear
Gas chromatographic determination of propoxyphene and norpropoxyphene in plasma.
    Journal of chromatography, 1977, Feb-11, Volume: 132, Issue:2

    Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Dextropropoxyphene; Humans; Male; Methods

1977
Gas chromatographic method for the determination of dextropropoxyphene and nordextropropoxyphene in human plasma, serum and urine.
    Journal of chromatography, 1977, Oct-21, Volume: 140, Issue:3

    Topics: Chromatography, Gas; Dextropropoxyphene; Humans; Methods; Oxidation-Reduction

1977
Propoxyphene and norpropoxyphene concentrations in blood and tissues in cases of fatal overdose.
    Clinical chemistry, 1976, Volume: 22, Issue:8

    Topics: Adult; Autopsy; Brain; Chromatography, Gas; Dextropropoxyphene; Female; Gastric Mucosa; Humans; Liver; Male; Middle Aged; Suicide

1976
Determination of dextropropoxyphene and norpropoxyphene in plasma by high-performance liquid chromatography.
    Journal of chromatography, 1992, Oct-02, Volume: 581, Issue:1

    Topics: Chromatography, High Pressure Liquid; Dextropropoxyphene; Humans; Reproducibility of Results; Spectrophotometry, Ultraviolet

1992
Simultaneous determination of propoxyphene and norpropoxyphene in biological samples by gas chromatography using an on-column injection technique with a fused-silica capillary column.
    Journal of chromatography, 1989, Jul-21, Volume: 491, Issue:2

    Topics: Adult; Chromatography, Gas; Dextropropoxyphene; Humans; Kidney; Lung; Male; Myocardium; Silicon Dioxide; Statistics as Topic

1989
Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in young and elderly volunteers after single and multiple dextropropoxyphene dosage.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:4

    Topics: Adult; Aged; Aging; Dextropropoxyphene; Female; Half-Life; Humans; Male

1989
The effect of ethanol intake on propoxyphene absorption and biotransformation in dogs.
    Alcoholism, clinical and experimental research, 1986, Volume: 10, Issue:4

    Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Dextropropoxyphene; Dogs; Ethanol; Injections, Intravenous; Intestinal Absorption; Kinetics

1986
Severe acute propoxyphene overdose: plasma concentrations of propoxyphene and norpropoxyphene and the effect of dopamine on circulatory failure.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:4

    Topics: Adult; Brain Diseases; Cardiovascular Diseases; Dextropropoxyphene; Dopamine; Female; Hemodynamics; Humans; Male; Middle Aged

1986
Lack of evidence of increased lethality due to propoxyphene overdose in the presence of ethanol in male Wistar rats.
    Archives of toxicology, 1985, Volume: 56, Issue:3

    Topics: Animals; Brain; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Lethal Dose 50; Liver; Male; Myocardium; Naloxone; Organ Size; Rats; Rats, Inbred Strains

1985
Liquid chromatographic determination of propoxyphene and norpropoxyphene in plasma and breast milk.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:1

    Topics: Chromatography, High Pressure Liquid; Dextropropoxyphene; Female; Humans; Milk, Human; Spectrophotometry, Ultraviolet

1985
Pharmacokinetic interaction of propoxyphene with ethanol.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:3

    Topics: Adult; Breath Tests; Dextropropoxyphene; Ethanol; Humans; Kinetics; Male

1985
In vitro effect of 4-methylpyrazole and pyruvate on ethanol interaction with propoxyphene metabolism in suspensions of isolated rat hepatocytes.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3

    Topics: Animals; Dextropropoxyphene; Drug Interactions; Ethanol; Fomepizole; In Vitro Techniques; Liver; Male; NADP; Pyrazoles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Vasopressins

1985
High-performance liquid chromatographic method for the determination of dextropropoxyphene and nordextropropoxyphene in serum.
    Journal of chromatography, 1985, Dec-13, Volume: 345, Issue:2

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Dextropropoxyphene; Humans; Spectrophotometry, Ultraviolet

1985
Measurement of dextropropoxyphene and nordextropropoxyphene in biological fluids.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Body Fluids; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dextropropoxyphene; Humans

1984
Self-poisoning with dextropropoxyphene and dextropropoxyphene compounds: the USA experience.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Autopsy; Child; Chromatography, Gas; Data Collection; Dextropropoxyphene; Female; Humans; Male; Middle Aged; Substance-Related Disorders; Time Factors; United States

1984
Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in elderly hospital patients after single and multiple doses of distalgesic. Preliminary analysis of results.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Acetaminophen; Aged; Dextropropoxyphene; Drug Combinations; Female; Half-Life; Humans; Kinetics; Male

1984
Dextropropoxyphene poisoning: problems with interpretation of analytical data.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Dextropropoxyphene; Humans; Liver

1984
Ethanol interaction with propoxyphene and norpropoxyphene metabolism in isolated rat hepatocytes.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18 Suppl 1

    Topics: Animals; Dextropropoxyphene; Drug Interactions; Ethanol; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains

1983
Excretion of propoxyphene and norpropoxyphene in breast milk.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:5

    Topics: Adult; Chromatography, High Pressure Liquid; Dextropropoxyphene; Female; Humans; Kinetics; Milk, Human

1984
Capillary and packed column GC determination of propoxyphene and norpropoxyphene in biological specimens: analytical problems and improvements.
    Journal of chromatographic science, 1983, Volume: 21, Issue:5

    Topics: Chromatography, Gas; Dextropropoxyphene; Humans; Methods; Toxicology

1983
Propoxyphene and norpropoxyphene kinetics after single and repeated doses of propoxyphene.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:2

    Topics: Adult; Dextropropoxyphene; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Mathematics; Models, Biological

1982
Maternal and fetal blood/brain distribution of d-propoxyphene and norpropoxyphene in rat and dog.
    Toxicology and applied pharmacology, 1981, Volume: 58, Issue:2

    Topics: Animals; Brain; Dextropropoxyphene; Dogs; Female; Fetal Blood; Maternal-Fetal Exchange; Pregnancy; Rats

1981
Acute effect of ethanol on hepatic first-pass elimination of propoxyphene in rats.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Animals; Biotransformation; Dealkylation; Dextropropoxyphene; Drug Interactions; Ethanol; Liver; Male; Rats; Rats, Inbred Strains

1981
Propoxyphene in postmortem toxicology 1976-1978.
    Journal of forensic sciences, 1981, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Dextropropoxyphene; Ethanol; Humans; Middle Aged; Substance-Related Disorders; Suicide; Time Factors

1981
TLC analysis of urine for benzoylecgonine and norpropoxyphene.
    Clinical toxicology, 1980, Volume: 16, Issue:1

    Topics: Chromatography, Thin Layer; Cocaine; Dextropropoxyphene; Humans; Methods

1980
Propoxyphene and norpropoxyphene: influence of type of controlled-release formulation on intra- and intersubject variations.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Biological Availability; Delayed-Action Preparations; Dextropropoxyphene; Female; Humans; Hydrogen-Ion Concentration; Individuality; Male; Middle Aged

1980
Simultaneous determination of dextromoramide, propoxyphene and norpropoxyphene in necropsic whole blood by liquid chromatography.
    Journal of chromatography, 1993, Jun-02, Volume: 615, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Dextromoramide; Dextropropoxyphene; Humans; Indicators and Reagents; Male; Spectrophotometry, Ultraviolet

1993
Extraction of selected drugs from serum using microwave irradiation.
    Forensic science international, 1996, Jul-31, Volume: 81, Issue:1

    Topics: Analgesics; Blood Chemical Analysis; Chromatography, Gas; Dextropropoxyphene; Diazepam; Humans; Lidocaine; Methadone; Microwaves; Narcotics; Nordazepam; Retrospective Studies

1996
Methadone block of K+ current in squid giant fiber lobe neurons.
    The Journal of general physiology, 1996, Volume: 107, Issue:2

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Chick Embryo; Decapodiformes; Dextropropoxyphene; Electric Stimulation; Hydrogen-Ion Concentration; Ion Channel Gating; Methadone; Muscle, Skeletal; Neurons; Patch-Clamp Techniques; Pituitary Gland; Potassium Channel Blockers; Rats; Receptors, Opioid, mu; Sensitivity and Specificity; Stereoisomerism; Temperature

1996
Gas chromatographic-mass spectrometric quantitation of dextropropoxyphene and norpropoxyphene in hair and whole blood after automated on-line solid-phase extraction. Application in twelve fatalities.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, May-08, Volume: 709, Issue:1

    Topics: Adult; Analgesics, Opioid; Automation; Dextropropoxyphene; Drug Overdose; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Heroin Dependence; Humans; Male; Sensitivity and Specificity; Substance-Related Disorders

1998
Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents.
    Cardiovascular research, 1999, Volume: 44, Issue:3

    Topics: Animals; Cation Transport Proteins; Dextropropoxyphene; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Opioid, mu; Trans-Activators; Transcriptional Regulator ERG; Xenopus

1999
Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel.
    Cardiovascular research, 2003, Apr-01, Volume: 58, Issue:1

    Topics: Amino Acid Motifs; Analgesics; Animals; Antidepressive Agents; Dextropropoxyphene; Female; Fluoxetine; Ion Channels; Mice; Mutagenesis, Site-Directed; Oocytes; Potassium Channels, Tandem Pore Domain; Sodium; Transcription, Genetic; Xenopus laevis

2003
Determination of dextropropoxyphene and nordextropropoxyphene in urine by liquid chromatography-electrospray ionization mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Aug-25, Volume: 794, Issue:1

    Topics: Dextropropoxyphene; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2003
Evaluation of the Triage PPY on-site testing device for the detection of dextropropoxyphene in urine.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: Analgesics, Opioid; Antibodies; Cross Reactions; Dextropropoxyphene; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Indicators and Reagents; Online Systems; Point-of-Care Systems; Reproducibility of Results; Substance Abuse Detection

2004
CYP3A4 mediates dextropropoxyphene N-demethylation to nordextropropoxyphene: human in vitro and in vivo studies and lack of CYP2D6 involvement.
    Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:10

    Topics: Administration, Oral; Adult; Aged; Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Female; Humans; Male; Metabolic Clearance Rate; Methylation; Microsomes, Liver; Middle Aged; Phenotype

2004
Death from undiagnosed glioblastoma multiforme and toxic self-medication presenting with concurrent dysfunctional behavior.
    Journal of forensic and legal medicine, 2008, Volume: 15, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Brain Edema; Brain Neoplasms; Dextropropoxyphene; Female; Forensic Pathology; Forensic Toxicology; Glioblastoma; Headache Disorders, Secondary; Humans; Hydrocodone; Intracranial Hemorrhages; Mental Disorders; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Self Medication; Vitreous Body

2008
Unstable propoxyphene metabolite excreted in human urine is detected by liquid chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:7

    Topics: Analgesics, Opioid; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Dextropropoxyphene; Humans; Indicators and Reagents; Reference Standards; Solutions; Tandem Mass Spectrometry

2009
Simultaneous quantitation of meperidine, normeperidine, tramadol, propoxyphene and norpropoxyphene in human plasma using solid-phase extraction and gas chromatography/mass spectrometry: Method validation and application to cardiovascular safety of therape
    Rapid communications in mass spectrometry : RCM, 2017, Sep-30, Volume: 31, Issue:18

    Topics: Analgesics, Opioid; Dextropropoxyphene; Drug Monitoring; Gas Chromatography-Mass Spectrometry; Heart; Humans; Meperidine; Solid Phase Extraction; Tramadol

2017