Page last updated: 2024-08-23

normeperidine and meperidine

normeperidine has been researched along with meperidine in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (57.14)	18.7374
1990's	19 (22.62)	18.2507
2000's	7 (8.33)	29.6817
2010's	8 (9.52)	24.3611
2020's	2 (2.38)	2.80

Authors

Authors	Studies
Foltz, RL; Kuhnert, BR; Kuhnert, PM; Lin, DC; Tu, AS	1
Austin, KL; Mather, LE; Stapleton, JV	2
Cederqvist, LL; Inturrisi, CE; Szeto, HH; Zervoudakis, IA	1
Siek, TJ	1
Inturrisi, CE; Szeto, HH	1
Jiraki, K	1
Carson, R; Grech, H; O'Mahoney, T; Pryle, BJ; Reynolds, F; Stoddart, PA	1
Aun, C; Chan, K; Houghton, IT; Lau, OW; Wong, YC	1
Deeg, MA; Rajamani, K	1
Scott, DT; Sinatra, RS; Wittels, B	1
Chaumont, AJ; Godelar, B; Kintz, P; Lugnier, AA; Mangin, P	1
Reutens, DC; Stewart-Wynne, EG	1
Kaine, CJ; Kuhnert, BR; Quinn, PG; Syracuse, CD	1
Bondesson, U; Boréus, LO; Hansdottir, V; Hedner, T; Mellstrand, T; Nordberg, G	1
Anderson, WH; Bucovaz, ET; Christie, RJ; Hess, LW; Martin, JN; Martin, RW; Morrison, JC; Stafford, DT; Wiser, WL	1
Dich-Nielsen, JO; Flachs, H; Hvidberg, EF; Jacobsen, J; Larsen, AB; Rosen, J	1
Chan, K; Jennings, F; Orme, ML; Tse, J	2
Appel, WC	1
Bonfiglio, MF; Mauro, VF; Spunt, AL	1
Armstrong, PJ; Bersten, A	1
Branch, RA; Herman, RJ; McAllister, CB; Wilkinson, GR	1
Kuhnert, BR; Kuhnert, PM; Philipson, EH; Syracuse, CD	2
Chalmers, JL; Guay, DR; Meatherall, RC	1
Boréus, LO; Kinn, AC; Nergårdh, A	1
Bucovaz, ET; Christie, RJ; Douvas, SG; Morrison, JC; Rhodes, PG; Wiser, WL	1
Adler, MW; Cowan, A; Tortella, FC	1
Boréus, LO	1
Yeh, SY	1
Leander, JD	2
Dykstra, LA; Leander, JD; Witkin, JM	1
Fagerlund, C; Hartvig, P	1
Boréus, LO; Ehrnebo, M; Sköldefors, E	1
Freeman, DS; Gjika, HB	1
Dahlström, B; Fagerlund, C; Hartvig, P; Tamsen, A	1
Benowitz, NL; Jacob, P; Pond, SM; Rigod, JF	1
Boréus, LO; Ehrnebo, M; Heyner, L; Holmberg, L; Odar-Cederlöf, I	1
Carter, RB; Leander, JD	1
Inturrisi, CE; Umans, JG	1
Anderson, GD; Dilts, PV; Lipshitz, J; Morrison, JC; Schneider, JM; Todd, EL	1
Belfrage, P; Boréus, LO; Hartvig, P; Irestedt, L; Raabe, N	1
Krebs, HA; Yeh, SY	1
Benowitz, NL; Jacob, P; Pond, SM; Rigod, J; Tong, T	1
Kretschzmar, KM; Pond, SM	1
Changchit, A; Krebs, HA; Yeh, SY	1
Chan, K	1
James, RC; Sweetman, BJ; Taber, DF; Verbeeck, RK; Wilkinson, GR	1
Hinnant, D	1
Shennib, H; Slinger, P; Wilson, S	1
Cmielewski, PL; Gourlay, GK; Harvey, I; Odontiadis, J; Plummer, JL	1
Hu, XY; Liu, F; Luo, Y	1
Jarvis, DA; Macintyre, PE; Stone, PA	1
Geller, RJ	1
Gin, T; Lam, KK; Ngan Kee, WD; Twyford, C	1
Boréus, LO; Jacobsson, G; Lilja, G; Matthiesen, AS; Nissen, E; Uvnäs-Moberg, K; Widström, AM	1
Marinella, MA	1
Bjorksten, AR; Ikeda, T; Larson, MD; Marder, D; Negishi, C; Sessler, DI; Tayefeh, F; Turakhia, M	1
Shen, B; Shen, M; Xiang, P	1
Boreus, LO; Ekblom, A; Engström, B; Söderlund, A; Valentin, A; Westman, L	1
McHugh, GJ	1
Bastani, B; Gellens, M; Hassan, H	1
Bertz, RJ; Davey, R; Kress, DR; Pau, A; Piscitelli, SC	1
Knight, B; Perry, G; Thomson, N	1
Peeters-Asdourian, C; Simopoulos, TT; Smith, HS; Stevens, DS	1
Bu, J; Huang, ZJ; Liu, W; Shen, BH; Shen, M; Wu, HJ; Xiang, P	1
McDermot, P	1
DEMOEN, PJ; HERMANS, BK; JAGENEAU, AH; JANSSEN, PA; LOOMANS, JL; RAEYMAEKERS, AH; SANCZUK, S; VAN DE WESTERINGH, C; WOUTERS, MS	1
ASATOOR, AM; LONDON, DR; MILNE, MD; SIMENHOFF, ML	1
DE CANNIERE, JH; DEMOEN, PJ; HERMANS, BK; JAGENEAU, AH; JANSSEN, PA; RAEYMAEKERS, AH; SANCZUK, S; VAN DE WESTERINGH, C; WOUTERS, MS	1
Flockhart, DA; Innocenti, F; Ramírez, J; Ratain, MJ; Relling, MV; Santucci, R; Schuetz, EG	1
Kruis, MR; van der Vegt, MH; van Kan, HJ; Vranken, JH	1
Gu, X; Gulasey, G; Housman, A; Izenwasser, S; Lomenzo, SA; Mobley, DL; Rhoden, JB; Savoie, CD; Trudell, ML; Wade, D	1
Al-Tamimi, Y; Hartmann, PE; Ilett, KF; O'Halloran, SJ; Paech, MJ	1
Fu, S; Lewis, J; Shimmon, R	1
Ho, ST; Hsu, CH; Lin, SH; Lin, TC; Lu, CC	1
Di Girolamo, G; Diez, RA; Fernández, N; Keller, GA; Olivera, NM; Quiroga, PN; Villa Etchegoyen, MC	1
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B	1
Di Girolamo, G; Diez, RA; Fernández, N; Keller, GA; Olivera, NM; Quiroga, PN	1
Cao, J; Du, Y; Jia, J; Liang, W; Sun, JH; Wang, YJ; Wang, YY; Wei, ZW; Wu, B; Yun, KM	1
Kul, A; Ozdemir, M; Sagirli, O	1
Hamamoto-Hardman, BD; Kass, PH; Knych, HK; McKemie, DS; Steffey, EP	1

Trials

6 trial(s) available for normeperidine and meperidine

Article	Year
Comparative plasma concentration profiles after i.v., i.m. and rectal administration of pethidine in children. British journal of anaesthesia, 1988, Volume: 60, Issue:6 Topics: Administration, Rectal; Adolescent; Child; Cholinesterase Inhibitors; Humans; Injections, Intramuscular; Injections, Intravenous; Meperidine; Time Factors	1988
Postthoracotomy pulmonary function: a comparison of epidural versus intravenous meperidine infusions. Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:2 Topics: Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Carbon Dioxide; Cholinesterase Inhibitors; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Lung; Male; Meperidine; Middle Aged; Pain Measurement; Prospective Studies; Thoracotomy; Vital Capacity	1995
Evaluation of a disposable device for patient-controlled epidural analgesia after caesarean section. Anaesthesia and intensive care, 1996, Volume: 24, Issue:1 Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Cesarean Section; Cholinesterase Inhibitors; Disposable Equipment; Equipment Design; Evaluation Studies as Topic; Female; Humans; Meperidine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Pregnancy	1996
Meperidine and alfentanil do not reduce the gain or maximum intensity of shivering. Anesthesiology, 1998, Volume: 88, Issue:4 Topics: Adjuvants, Anesthesia; Adult; Alfentanil; Anesthetics, Intravenous; Body Temperature Regulation; Cholinesterase Inhibitors; Hemodynamics; Humans; Infusions, Intravenous; Male; Meperidine; Oxygen Consumption; Shivering	1998
A comparison of 50, 100 and 200 mg of intra-articular pethidine during knee joint surgery, a controlled study with evidence for local demethylation to norpethidine. Pain, 1999, Volume: 80, Issue:1-2 Topics: Adult; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Arthroscopy; Dealkylation; Double-Blind Method; Female; Humans; Injections, Intra-Articular; Joint Diseases; Knee Joint; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Prilocaine; Synovial Fluid	1999
The effect of ritonavir on the pharmacokinetics of meperidine and normeperidine. Pharmacotherapy, 2000, Volume: 20, Issue:5 Topics: Adult; Analgesics, Opioid; Area Under Curve; Cholinesterase Inhibitors; Confidence Intervals; Cross-Over Studies; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Male; Meperidine; Ritonavir	2000

Other Studies

78 other study(ies) available for normeperidine and meperidine

Article	Year
Meperidine and normeperidine levels following meperidine administration during labor. I. Mother. American journal of obstetrics and gynecology, 1979, Apr-15, Volume: 133, Issue:8 Topics: Adult; Chromatography, Gas; Female; Humans; Kinetics; Labor, Obstetric; Mass Spectrometry; Meperidine; Pregnancy	1979
A pharmacokinetic approach to postoperative pain: continuous infusion of pethidine. Anaesthesia and intensive care, 1979, Volume: 7, Issue:1 Topics: Adult; Aged; Blood Pressure; Computers; Drug Administration Schedule; Female; Humans; Hysterectomy; Infusions, Parenteral; Meperidine; Middle Aged; Pain, Postoperative	1979
Amniotic fluid transfer of meperidine from maternal plasma in early pregnancy. Obstetrics and gynecology, 1978, Volume: 52, Issue:1 Topics: Amniotic Fluid; Female; Humans; Maternal-Fetal Exchange; Meperidine; Pregnancy; Pregnancy Trimester, Second; Time Factors	1978
The analysis of meperidine and normeperidine in biological specimens. Journal of forensic sciences, 1978, Volume: 23, Issue:1 Topics: Chromatography, Gas; Chromatography, Thin Layer; Humans; Mass Spectrometry; Meperidine; Tissue Distribution	1978
Simultaneous determination of meperidine and normeperidine in biofluids. Journal of chromatography, 1976, Volume: 125, Issue:3 Topics: Amniotic Fluid; Animals; Cats; Chromatography, Gas; Chromatography, Liquid; Female; Humans; Male; Meperidine; Methods; Microchemistry; Neoplasms; Pregnancy; Solvents	1976
Lethal effects of normeperidine. The American journal of forensic medicine and pathology, 1992, Volume: 13, Issue:1 Topics: Adult; Cholinesterase Inhibitors; Half-Life; Humans; Kidney Failure, Chronic; Male; Meperidine; Substance-Related Disorders	1992
Toxicity of norpethidine in sickle cell crisis. BMJ (Clinical research ed.), 1992, Jun-06, Volume: 304, Issue:6840 Topics: Adolescent; Adult; Anemia, Sickle Cell; Cholinesterase Inhibitors; Female; Humans; Male; Meperidine; Middle Aged; Seizures	1992
Protein binding characterization of pethidine and norpethidine and lack of interethnic variability. Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:4 Topics: Analgesia; Asian People; Binding, Competitive; Blood Proteins; Cholinesterase Inhibitors; Genetic Variation; Humans; Injections, Intramuscular; Kinetics; Male; Meperidine; Orosomucoid; Protein Binding; Serum Albumin; White People	1991
Normeperidine-induced seizures in hereditary coproporphyria. Southern medical journal, 1990, Volume: 83, Issue:11 Topics: Adult; Cholinesterase Inhibitors; Coproporphyrins; Female; Humans; Infant; Liver Diseases; Meperidine; Porphyrias; Seizures	1990
Exogenous opioids in human breast milk and acute neonatal neurobehavior: a preliminary study. Anesthesiology, 1990, Volume: 73, Issue:5 Topics: Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthesia, Epidural; Behavior; Cesarean Section; Cholinesterase Inhibitors; Colostrum; Female; Humans; Infant, Newborn; Meperidine; Milk, Human; Morphine; Pain, Postoperative; Pregnancy	1990
Simultaneous determination of pethidine (meperidine), phenoperidine, and norpethidine (normeperidine), their common metabolite, by gas chromatography with selective nitrogen detection. Forensic science international, 1989, Volume: 43, Issue:3 Topics: Cholinesterase Inhibitors; Chromatography, Gas; Humans; Meperidine; Phenoperidine; Predictive Value of Tests	1989
Norpethidine induced myoclonus in a patient with renal failure. Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:12 Topics: Adult; Cholinesterase Inhibitors; Humans; Kidney Failure, Chronic; Male; Meperidine; Myoclonus	1989
Measurement of meperidine and normeperidine in human breast milk by selected ion monitoring. Biomedical & environmental mass spectrometry, 1986, Volume: 13, Issue:3 Topics: Female; Gas Chromatography-Mass Spectrometry; Humans; Meperidine; Milk, Human	1986
CSF and plasma pharmacokinetics of pethidine and norpethidine in man after epidural and intrathecal administration of pethidine. European journal of clinical pharmacology, 1988, Volume: 34, Issue:6 Topics: Female; Humans; Injections, Epidural; Injections, Spinal; Male; Meperidine	1988
Meperidine and normeperidine distribution in the rhesus monkey. Journal of perinatology : official journal of the California Perinatal Association, 1988,Winter, Volume: 8, Issue:1 Topics: Animals; Brain; Female; Fetus; Macaca; Macaca mulatta; Maternal-Fetal Exchange; Meperidine; Pregnancy; Pregnancy, Animal; Tissue Distribution	1988
Influence of urinary pH on pethidine kinetics in healthy volunteer subjects. 2. A study of ten Chinese subjects. Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:1 Topics: Adult; China; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Kinetics; Male; Meperidine; Urine	1987
Possible roles of normeperidine and hyponatremia in a postoperative death. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1987, Nov-15, Volume: 137, Issue:10 Topics: Adult; Brain Edema; Brain Stem; Cholecystectomy; Encephalocele; Female; Headache; Humans; Hyponatremia; Meperidine; Pain, Postoperative; Postoperative Complications	1987
Meperidine-induced seizure in a patient without renal dysfunction or sickle cell anemia. Clinical pharmacy, 1986, Volume: 5, Issue:10 Topics: Adult; Drug Interactions; Female; Humans; Meperidine; Prochlorperazine; Seizures	1986
Normeperidine toxicity. Anesthesia and analgesia, 1986, Volume: 65, Issue:5 Topics: Adult; Biotransformation; Colonic Neoplasms; Diazepam; Female; Humans; Injections, Intramuscular; Meperidine; Obesity; Oxygen; Pain, Postoperative; Postoperative Period; Seizures	1986
Effects of age on meperidine disposition. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:1 Topics: Administration, Oral; Adult; Age Factors; Aged; Biological Availability; Humans; Infusions, Parenteral; Injections, Intramuscular; Kinetics; Male; Meperidine; Middle Aged	1985
Disposition of meperidine and normeperidine following multiple doses during labor. I. Mother. American journal of obstetrics and gynecology, 1985, Feb-01, Volume: 151, Issue:3 Topics: Adolescent; Adult; Female; Half-Life; Humans; Labor, Obstetric; Meperidine; Postpartum Period; Pregnancy	1985
Disposition of meperidine and normeperidine following multiple doses during labor. II. Fetus and neonate. American journal of obstetrics and gynecology, 1985, Feb-01, Volume: 151, Issue:3 Topics: Female; Fetal Blood; Fetus; Humans; Infant, Newborn; Kinetics; Labor, Obstetric; Maternal-Fetal Exchange; Meperidine; Pregnancy	1985
Analysis of meperidine and normeperidine in serum and urine by high-performance liquid chromatography. Journal of chromatography, 1985, Feb-27, Volume: 338, Issue:1 Topics: Adult; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Humans; Kinetics; Male; Meperidine; Spectrophotometry, Ultraviolet	1985
Influence of urinary pH on pethidine kinetics in healthy volunteer subjects. Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:5 Topics: Adult; Female; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Male; Meperidine; Metabolic Clearance Rate; Models, Biological; Urine	1985
Effects of narcotic analgesics, especially pethidine and norpethidine, on renal pelvic smooth muscle in patients with hydronephrosis. European journal of clinical pharmacology, 1982, Volume: 22, Issue:5 Topics: Analgesics, Opioid; Humans; Hydronephrosis; In Vitro Techniques; Kidney Pelvis; Meperidine; Muscle Relaxation; Muscle, Smooth	1982
Meperidine and normeperidine metabolism in the rhesus monkey. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1984, Volume: 22, Issue:5 Topics: Animals; Animals, Newborn; Apgar Score; Female; Fetus; Humans; Macaca; Macaca mulatta; Maternal-Fetal Exchange; Meperidine; Models, Biological; Pregnancy; Pregnancy, Animal; Time Factors	1984
Studies on the excitatory and inhibitory influence of intracerebroventricularly injected opioids on seizure thresholds in rats. Neuropharmacology, 1984, Volume: 23, Issue:7A Topics: Animals; Brain; Dose-Response Relationship, Drug; Flurothyl; Injections, Intraventricular; Male; Meperidine; Naloxone; Narcotics; Pentazocine; Rats; Rats, Inbred Strains; Seizures; Thebaine	1984
Placental drug transfer: methodological and therapeutic aspects. Developmental pharmacology and therapeutics, 1984, Volume: 7 Suppl 1 Topics: Ampicillin; Female; Humans; Kinetics; Maternal-Fetal Exchange; Mathematics; Meperidine; Pharmaceutical Preparations; Placenta; Pregnancy	1984
Metabolism of meperidine in several animal species. Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:12 Topics: Animals; Biotransformation; Cats; Chromatography, Thin Layer; Dogs; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Hydrolysis; Meperidine; Monoamine Oxidase Inhibitors; Rabbits; Rats; Species Specificity	1984
Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam. Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:1 Topics: Animals; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Male; Meperidine; Methadone; Morphine; Pentobarbital	1983
Modification of behavioral effects of morphine, meperidine and normeperidine by naloxone and by morphine tolerance. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2 Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Male; Meperidine; Morphine; Naloxone; Reaction Time; Saimiri	1983
A simplified method for the gas chromatographic determination of pethidine and norpethidine after derivatization with trichloroethyl chloroformate. Journal of chromatography, 1983, May-13, Volume: 274 Topics: Chloroform; Chromatography, Gas; Humans; Meperidine; Phosgene	1983
Appearance of pethidine and norpethidine in cerebrospinal fluid of man following intramuscular injection of pethidine. Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:3 Topics: Adult; Blood-Brain Barrier; Cholinesterase Inhibitors; Female; Humans; Injections, Intramuscular; Male; Meperidine; Middle Aged; Time Factors	1983
Radioimmunoassay of N-substituted phenylpiperidine carboxylic acid esters and dealkylated metabolites. Methods in enzymology, 1982, Volume: 84 Topics: Animals; Chromatography, High Pressure Liquid; Cross Reactions; Diphenoxylate; Humans; Isonipecotic Acids; Meperidine; Microsomes, Liver; Rabbits; Radioimmunoassay	1982
Pharmacokinetics of pethidine during anaesthesia and patient-controlled analgesic therapy. Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 74 Topics: Anesthesia; Biotransformation; Humans; Kinetics; Meperidine; Pain, Postoperative	1982
Gas chromatographic analysis of meperidine and normeperidine: determination in blood after a single dose of meperidine. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:2 Topics: Adult; Chromatography, Gas; Humans; Male; Meperidine	1982
Comparative disposition of pethidine and norpethidine in old and young patients. European journal of clinical pharmacology, 1982, Volume: 22, Issue:2 Topics: Adolescent; Adult; Aging; Female; Half-Life; Humans; Injections, Intravenous; Male; Meperidine; Time Factors	1982
Interaction of diazepam with meperidine or normeperidine on analgesia and lethality. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:6 Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Meperidine; Nociceptors; Rats; Rats, Inbred Strains; Seizures	1982
Attenuation of normeperidine's suppressing effect on schedule-controlled behavior. European journal of pharmacology, 1982, Jun-16, Volume: 81, Issue:1 Topics: Animals; Clonazepam; Columbidae; Conditioning, Psychological; Diazepam; Male; Meperidine; Pentobarbital	1982
Antinociceptive activity and toxicity of meperidine and normeperidine in mice. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1 Topics: Analgesics; Animals; Convulsants; Injections, Intraventricular; Injections, Subcutaneous; Male; Meperidine; Mice; Morphine; Naloxone	1982
Meperidine metabolism in the parturient. Obstetrics and gynecology, 1982, Volume: 59, Issue:3 Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Cholinesterase Inhibitors; Chromatography, Gas; Female; Fetal Blood; Humans; Meperidine; Postpartum Period; Pregnancy; Time Factors	1982
Neonatal depression after obstetrical analgesia with pethidine. The role of the injection-delivery time interval and of the plasma concentrations of pethidine and norpethidine. Acta obstetricia et gynecologica Scandinavica, 1981, Volume: 60, Issue:1 Topics: Anesthesia, Obstetrical; Female; Fetal Blood; Humans; Infant, Newborn; Meperidine; Naloxone; Pregnancy; Respiration; Respiratory Distress Syndrome, Newborn; Time Factors	1981
TLC identification adn GLC determination of meperidine and its metabolites in biological fluids. Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:5 Topics: Animals; Biotransformation; Chromatography, Gas; Chromatography, Thin Layer; Male; Meperidine; Rats	1981
Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects. Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:2 Topics: Administration, Oral; Adult; Biotransformation; Dealkylation; Humans; Injections, Intravenous; Kinetics; Liver Cirrhosis, Alcoholic; Male; Meperidine; Middle Aged	1981
Effect of phenytoin on meperidine clearance and normeperidine formation. Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:5 Topics: Adult; Drug Interactions; Humans; Male; Meperidine; Metabolic Clearance Rate; Phenytoin	1981
Urinary excretion of meperidine and its metabolites. Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:8 Topics: Animals; Cats; Dogs; Female; Guinea Pigs; Hydrogen-Ion Concentration; Male; Meperidine; Mice; Rabbits; Rats; Rats, Inbred Strains; Species Specificity	1981
Disposition of pethidine in man under acidic urinary PH. I. Plasma level and urinary elimination of pethidine and norpethidine. Journal of clinical and hospital pharmacy, 1981, Volume: 6, Issue:2 Topics: Administration, Oral; Adult; Biotransformation; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Liver; Male; Meperidine; Time Factors	1981
The determination of meperidine, noremeperidine and deuterated analogs in blood and plasma by gas chromatography mass spectrometry selected ion monitoring. Biomedical mass spectrometry, 1980, Volume: 7, Issue:2 Topics: Gas Chromatography-Mass Spectrometry; Humans; Ions; Meperidine	1980
Rate of formation of norpethidine from pethidine. British journal of anaesthesia, 1981, Volume: 53, Issue:3 Topics: Female; Humans; Hysterectomy; Infusions, Parenteral; Injections, Intramuscular; Meperidine	1981
Detecting the dangers of meperidine. Nursing, 1995, Volume: 25, Issue:6 Topics: Adult; Humans; Male; Meperidine; Nursing Assessment; Tremor	1995
Behavioural effects of norpethidine, a metabolite of pethidine, in rats. Toxicology, 1995, Jan-06, Volume: 95, Issue:1-3 Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Meperidine; Physostigmine; Random Allocation; Rats; Rats, Wistar; Reserpine	1995
[Analysis of meperidine and its metabolites in urine of an addict by GC/FID and GC/MS]. Yao xue xue bao = Acta pharmaceutica Sinica, 1994, Volume: 29, Issue:2 Topics: Cholinesterase Inhibitors; Chromatography; Gas Chromatography-Mass Spectrometry; Humans; Meperidine	1994
Norpethidine toxicity and patient controlled analgesia. British journal of anaesthesia, 1993, Volume: 71, Issue:5 Topics: Adult; Analgesia, Patient-Controlled; Cholinesterase Inhibitors; Female; Humans; Meperidine; Middle Aged; Pain, Postoperative	1993
Meperidine in patient-controlled analgesia: a near-fatal mishap. Anesthesia and analgesia, 1993, Volume: 76, Issue:3 Topics: Acute Kidney Injury; Adult; Analgesia, Patient-Controlled; Humans; Male; Meperidine; Pain, Postoperative	1993
Effects of routinely given pethidine during labour on infants' developing breastfeeding behaviour. Effects of dose-delivery time interval and various concentrations of pethidine/norpethidine in cord plasma. Acta paediatrica (Oslo, Norway : 1992), 1997, Volume: 86, Issue:2 Topics: Analgesia, Obstetrical; Analgesics; Breast Feeding; Delivery, Obstetric; Female; Fetal Blood; Humans; Infant, Newborn; Meperidine; Pregnancy; Sucking Behavior; Time Factors	1997
Meperidine-induced generalized seizures with normal renal function. Southern medical journal, 1997, Volume: 90, Issue:5 Topics: Abdominal Pain; Adult; Analgesics, Opioid; Cholinesterase Inhibitors; Chronic Disease; Epilepsy, Tonic-Clonic; Humans; Kidney; Male; Meperidine; Pain; Pancreatitis	1997
[Analysis and assessment of meperidine and normeperidine concentrations in urine]. Fa yi xue za zhi, 1997, Volume: 13, Issue:1 Topics: Adult; Humans; Meperidine; Substance Abuse Detection; Substance-Related Disorders	1997
Norpethidine accumulation and generalized seizure during pethidine patient-controlled analgesia. Anaesthesia and intensive care, 1999, Volume: 27, Issue:3 Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Humans; Ileostomy; Laparotomy; Meperidine; Seizures	1999
Successful treatment of normeperidine neurotoxicity by hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 35, Issue:1 Topics: Aged; Analgesics, Opioid; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Kidney Failure, Chronic; Meperidine; Metabolic Clearance Rate; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis	2000
Seizures due to norpethidine toxicity. Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:4 Topics: Cholinesterase Inhibitors; Epilepsy, Tonic-Clonic; Female; Humans; Meperidine; Middle Aged	2000
Use of meperidine in patient-controlled analgesia and the development of a normeperidine toxic reaction. Archives of surgery (Chicago, Ill. : 1960), 2002, Volume: 137, Issue:1 Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Case-Control Studies; Central Nervous System Diseases; Dose-Response Relationship, Drug; Female; Humans; Male; Meperidine; Middle Aged; Pain, Postoperative; Retrospective Studies; Time Factors	2002
[Segmental analysis of hair from meperidine abusers and evaluation of the results]. Fa yi xue za zhi, 1999, Volume: 15, Issue:4 Topics: Female; Forensic Medicine; Hair; Humans; Meperidine; Substance Abuse Detection	1999
Recognizing normeperidine toxicity. Nursing, 2003, Volume: 33, Issue:3 Topics: Cholinesterase Inhibitors; Drug-Related Side Effects and Adverse Reactions; Humans; Meperidine	2003
Compounds related to pethidine. I. Mannich bases derived from norpethidine and acetophenones. Journal of medicinal and pharmaceutical chemistry, 1959, Volume: 1, Issue:1 Topics: Acetophenones; Ketones; Mannich Bases; Meperidine	1959
The excretion of pethidine and its derivatives. British journal of pharmacology and chemotherapy, 1963, Volume: 20 Topics: Adjuvants, Immunologic; Ammonium Chloride; Behavior, Addictive; Dinitrobenzenes; Drug-Related Side Effects and Adverse Reactions; Humans; Meperidine	1963
Compounds related to pethidine. III. Basic ketones derived from norpethidine. Journal of medicinal and pharmaceutical chemistry, 1960, Volume: 2 Topics: Ketones; Meperidine	1960
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9 Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Meperidine; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Thiotepa	2004
Plasma concentrations of meperidine and normeperidine following continuous intrathecal meperidine in patients with neuropathic cancer pain. Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:5 Topics: Aged; Analgesics, Opioid; Female; Humans; Injections, Spinal; Male; Meperidine; Middle Aged; Neoplasms; Pain, Intractable; Quality of Life	2005
Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands. Bioorganic & medicinal chemistry, 2010, Dec-01, Volume: 18, Issue:23 Topics: Esters; Ligands; Meperidine; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship	2010
Estimation of infant dose and exposure to pethidine and norpethidine via breast milk following patient-controlled epidural pethidine for analgesia post caesarean delivery. International journal of obstetric anesthesia, 2011, Volume: 20, Issue:2 Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Breast Feeding; Cesarean Section; Female; Humans; Infant, Newborn; Meperidine; Milk, Human; Pain, Postoperative; Pregnancy	2011
Pethidinic acid: corroboration of a doctor's denial of pethidine re-use. Journal of analytical toxicology, 2013, Volume: 37, Issue:3 Topics: Analgesics, Opioid; Biomarkers; Biotransformation; Calibration; Humans; Limit of Detection; Meperidine; Opioid-Related Disorders; Physician Impairment; Predictive Value of Tests; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Urinalysis	2013
Clearance of meperidine and its metabolite normeperidine in hemodialysis patients with chronic noncancer pain. Journal of pain and symptom management, 2014, Volume: 47, Issue:4 Topics: Abdominal Pain; Adult; Analgesics, Opioid; Back Pain; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chronic Pain; Female; Humans; Male; Meperidine; Metabolic Clearance Rate; Middle Aged; Pancreatitis, Chronic; Renal Dialysis; Time Factors	2014
Meperidine-induced QTc-interval prolongation: prevalence, risk factors, and correlation to plasma drug and metabolite concentrations . International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:3 Topics: Action Potentials; Aged; Aged, 80 and over; Analgesics, Opioid; Argentina; Biotransformation; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Long QT Syndrome; Longitudinal Studies; Male; Meperidine; Middle Aged; Prevalence; Prospective Studies; Renal Insufficiency; Risk Assessment; Risk Factors	2017
LC-MS-MS Method for the Analysis of Miscellaneous Drugs in Wastewater During Football Games III. Journal of analytical toxicology, 2016, Volume: 40, Issue:8 Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Residues; Fentanyl; Football; Humans; Illicit Drugs; Limit of Detection; Meperidine; Methadone; Mississippi; Phencyclidine; Pyrrolidines; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater	2016
Simultaneous quantitation of meperidine, normeperidine, tramadol, propoxyphene and norpropoxyphene in human plasma using solid-phase extraction and gas chromatography/mass spectrometry: Method validation and application to cardiovascular safety of therape Rapid communications in mass spectrometry : RCM, 2017, Sep-30, Volume: 31, Issue:18 Topics: Analgesics, Opioid; Dextropropoxyphene; Drug Monitoring; Gas Chromatography-Mass Spectrometry; Heart; Humans; Meperidine; Solid Phase Extraction; Tramadol	2017
Pharmacokinetics of meperidine (pethidine) in rabbit oral fluid: correlation with plasma concentrations after controlled administration. Die Pharmazie, 2018, 06-01, Volume: 73, Issue:6 Topics: Administration, Intravenous; Analgesics, Opioid; Animals; Drug Monitoring; Gas Chromatography-Mass Spectrometry; Male; Meperidine; Rabbits; Reproducibility of Results; Time Factors	2018
Determination of pethidine of abuse and relevant metabolite norpethidine in urine by ultra-performance liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2020, Jul-15, Volume: 186 Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Female; Humans; Limit of Detection; Male; Meperidine; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry	2020
Meperidine pharmacokinetics and effects on physiologic parameters and thermal threshold following intravenous administration of three doses to horses. BMC veterinary research, 2020, Oct-01, Volume: 16, Issue:1 Topics: Administration, Intravenous; Analgesics, Opioid; Animals; Central Nervous System; Female; Heart Rate; Horses; Hot Temperature; Male; Meperidine; Nociception; Urticaria	2020