norketobemidone has been researched along with meperidine in 4 studies
| Studies (norketobemidone) | Trials (norketobemidone) | Recent Studies (post-2010) (norketobemidone) | Studies (meperidine) | Trials (meperidine) | Recent Studies (post-2010) (meperidine) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 5,748 | 1,228 | 343 |
| Protein | Taxonomy | norketobemidone (IC50) | meperidine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.4075 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.5 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.435 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.5 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.3236 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrahamsson, L; Ahnfelt, NO; Bondesson, U; Hartvig, P | 1 |
| Christensen, CB; Christrup, LL; Kristensen, K; Nielsen, LC | 1 |
| Al-Shurbaji, A; Annas, A; Artursson, P; Lazorova, L; Svensson, JO; Yasar, U | 1 |
| Bergquist, J; Lanças, FM; Santos-Neto, AJ; Sjöberg, PJ | 1 |
4 other study(ies) available for norketobemidone and meperidine
| Article | Year |
|---|---|
Simultaneous determination of ketobemidone and its N-demethylated metabolite in patient plasma samples by gas chromatography mass spectrometry with selected ion monitoring.
Topics: Analgesics, Opioid; Gas Chromatography-Mass Spectrometry; Humans; Ions; Isonipecotic Acids; Meperidine; Phenols | 1983 |
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene.
Topics: Allylamine; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Isonipecotic Acids; Meperidine; Parasympatholytics; Phenols; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Caco-2 Cells; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isonipecotic Acids; Ketoconazole; Kinetics; Meperidine; Microsomes, Liver; Mutagenesis, Site-Directed; Phenols; Substrate Specificity; Sulfaphenazole; Troleandomycin; Verapamil | 2005 |
Simultaneous analysis of five antidepressant drugs using direct injection of biofluids in a capillary restricted-access media-liquid chromatography-tandem mass spectrometry system.
Topics: Antidepressive Agents; Chromatography, High Pressure Liquid; Isonipecotic Acids; Meperidine; Phenols; Reproducibility of Results; Tandem Mass Spectrometry | 2008 |