norketamine has been researched along with ticlopidine in 1 studies
| Studies (norketamine) | Trials (norketamine) | Recent Studies (post-2010) (norketamine) | Studies (ticlopidine) | Trials (ticlopidine) | Recent Studies (post-2010) (ticlopidine) |
|---|---|---|---|---|---|
| 220 | 32 | 122 | 10,289 | 1,893 | 4,671 |
| Protein | Taxonomy | norketamine (IC50) | ticlopidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.382 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 6.2928 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.304 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.175 | |
| Cytochrome P450 2B6 | Homo sapiens (human) | 0.405 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.6678 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.426 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagelberg, NM; Laine, K; Neuvonen, PJ; Olkkola, KT; Peltoniemi, MA; Reponen, P; Saari, TI; Turpeinen, M | 1 |
1 trial(s) available for norketamine and ticlopidine
| Article | Year |
|---|---|
Exposure to oral S-ketamine is unaffected by itraconazole but greatly increased by ticlopidine.
Topics: Administration, Oral; Adult; Anesthetics, Dissociative; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Female; Humans; Itraconazole; Ketamine; Male; Oxidoreductases, N-Demethylating; Platelet Aggregation Inhibitors; Ticlopidine; Young Adult | 2011 |