norketamine has been researched along with morphine in 3 studies
| Studies (norketamine) | Trials (norketamine) | Recent Studies (post-2010) (norketamine) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 220 | 32 | 122 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | norketamine (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crooks, PA; Holtman, JR; Johnson-Hardy, J; Wala, EP | 1 |
| Jokinen, V; Kalso, EA; Lilius, TO; Neuvonen, MS; Niemi, M; Rauhala, PV | 1 |
| Kalso, E; Kangas, E; Lilius, T; Niemi, M; Rauhala, P | 1 |
3 other study(ies) available for norketamine and morphine
| Article | Year |
|---|---|
Interaction between morphine and norketamine enantiomers in rodent models of nociception.
Topics: Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Formaldehyde; Ketamine; Male; Morphine; Motor Activity; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Stereoisomerism | 2008 |
Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Drug Tolerance; Injections, Subcutaneous; Ketamine; Liver; Morphine; Morphine Derivatives; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2015 |
Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine: from behaviour to drug availability.
Topics: Analgesics; Analgesics, Opioid; Animals; Drug Interactions; Drug Tolerance; Ketamine; Male; Models, Animal; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley | 2018 |