norketamine has been researched along with 6-hydroxynorketamine in 6 studies
| Studies (norketamine) | Trials (norketamine) | Recent Studies (post-2010) (norketamine) | Studies (6-hydroxynorketamine) | Trials (6-hydroxynorketamine) | Recent Studies (post-2010) (6-hydroxynorketamine) |
|---|---|---|---|---|---|
| 220 | 32 | 122 | 38 | 2 | 36 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baillie, TA; Leung, LY | 1 |
| Brutsche, NE; Ibrahim, L; Luckenbaugh, DA; Mager, DE; Moaddel, R; Venkata, SL; Wainer, IW; Zarate, CA; Zhao, X | 1 |
| Dahan, A; van Velzen, M | 1 |
| Bernier, M; Green, CE; Khadeer, M; Moaddel, R; O'Loughlin, K; Paul, RK; Sanghvi, M; Singh, NS; Torjman, MC; Wainer, IW | 1 |
| Chaki, S; Hashimoto, K; Koike, H; Mizuno-Yasuhira, A; Qu, Y; Toki, H; Yamaguchi, JI; Yang, C | 1 |
| Burke, AK; Choo, TH; Cooper, TB; Galfalvy, HC; Grunebaum, MF; Mann, JJ; Parris, MS; Suckow, RF | 1 |
2 trial(s) available for norketamine and 6-hydroxynorketamine
| Article | Year |
|---|---|
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
Topics: Adult; Algorithms; Antidepressive Agents; Biotransformation; Bipolar Disorder; Cross-Over Studies; Double-Blind Method; Drug Resistance; Female; Humans; Hydroxylation; Infusions, Parenteral; Ketamine; Male; Middle Aged; Models, Biological; Young Adult | 2012 |
Ketamine metabolite pilot study in a suicidal depression trial.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Humans; Infusions, Parenteral; Ketamine; Midazolam; Outcome Assessment, Health Care; Pilot Projects; Severity of Illness Index; Suicidal Ideation | 2019 |
4 other study(ies) available for norketamine and 6-hydroxynorketamine
| Article | Year |
|---|---|
Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine.
Topics: Anesthesia; Animals; Brain; Ketamine; Male; Rats; Rats, Inbred Strains | 1986 |
Ketamine metabolomics in the treatment of major depression.
Topics: Animals; Excitatory Amino Acid Antagonists; Ketamine; Male; TOR Serine-Threonine Kinases | 2014 |
(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.
Topics: Aconitine; Animals; Blotting, Western; Brain; Excitatory Amino Acid Antagonists; Ketamine; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; PC12 Cells; Phosphorylation; Prefrontal Cortex; Rats; Rats, Wistar; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.
Topics: Animals; Antidepressive Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Depressive Disorder; Inflammation; Ketamine; Lipopolysaccharides; Male; Mice, Inbred C57BL; Mice, Inbred ICR | 2018 |