Page last updated: 2024-08-24

norharman and harmaline

norharman has been researched along with harmaline in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Deng, Y; Duan, J; Kesuma, D; Qi, RZ; Sim, MM; Song, Y; Teng, SF; Wang, J; Wang, JH1
Amado, Mdel R; Carrillo, AK; Galarreta, BC; Maruenda, H; Sanchez, L; Sifuentes, R1
Jiang, X; Liu, J; Peng, L; Peng, S; Zhang, X; Zhao, M; Zheng, M1
Li, C; Liu, J; Peng, S; Wang, Y; Wu, J; Zhang, X; Zhao, M; Zheng, M1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dai, JK; Dan, WJ; Wan, JB1
Bourke, CA; Carrigan, MJ; Dixon, RJ1
Oderfeld-Nowak, B; Rommelspacher, H; Skup, M1
Pineda, J; Ruiz-Durántez, E; Ugedo, L1
Beach, JW; Collins, MA; Gearhart, DA; Hwang, YI; Neafsey, EJ; Schwarz, J; Storch, A1
Benavente, F; Gagliardi, LG; Tascón, M; Vizioli, NM1
Chen, W; Cheng, X; Huang, L; Jiang, B; Li, S; Meng, L; Wang, C; Wang, H; Wang, Z; Zou, N1
Cabrerizo, FM; Denofrio, MP; Erra-Balsells, R; García Einschlag, FS; Rasse-Suriani, FAO; Schmidt De León, T; Villarruel, F1
Deng, S; Lv, X; Ma, XC; Sun, CP; Wei, F; Yi, J; Zhang, BJ; Zhao, WY1

Reviews

1 review(s) available for norharman and harmaline

ArticleYear
Natural and synthetic β-carboline as a privileged antifungal scaffolds.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Antifungal Agents; Biological Products; Carbolines; Drug Discovery; Female; Humans; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycoses; Protein Binding; Signal Transduction; Structure-Activity Relationship

2022

Other Studies

13 other study(ies) available for norharman and harmaline

ArticleYear
Beta-carbolines as specific inhibitors of cyclin-dependent kinases.
    Bioorganic & medicinal chemistry letters, 2002, Apr-08, Volume: 12, Issue:7

    Topics: Carbolines; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Protein Serine-Threonine Kinases

2002
The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.
    Bioorganic & medicinal chemistry, 2008, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Biological Products; Enzyme Inhibitors; Flavins; Harmaline; Indole Alkaloids; Leishmania; NADH, NADPH Oxidoreductases; Quinolines; Trypanocidal Agents; Trypanosoma cruzi

2008
A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Amino Acids; Animals; Carbolines; Fibrinolytic Agents; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Swine

2010
A class of novel N-(1-methyl-β-carboline-3-carbonyl)-N'-(aminoacid-acyl)-hydrazines: aromatization leaded design, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: Animals; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Hydrazines; Male; Models, Molecular; Molecular Conformation; Platelet Aggregation; Platelet Aggregation Inhibitors; Quantitative Structure-Activity Relationship; Rats; Swine; Thrombosis

2011
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Upper motor neurone effects in sheep of some beta-carboline alkaloids identified in zygophyllaceous plants.
    Australian veterinary journal, 1990, Volume: 67, Issue:7

    Topics: Alkaloids; Animals; Carbolines; Female; Harmaline; Harmine; Locomotion; Motor Neurons; Plants, Toxic; Sheep

1990
In vitro studies on the effect of beta-carbolines on the activities of acetylcholinesterase and choline acetyltransferase and on the muscarinic receptor binding of the rat brain.
    Journal of neurochemistry, 1983, Volume: 41, Issue:1

    Topics: Acetylcholinesterase; Alkaloids; Animals; Brain; Carbolines; Cattle; Choline O-Acetyltransferase; Erythrocytes; Harmaline; Harmine; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Structure-Activity Relationship

1983
Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats.
    Neuroscience letters, 2001, Aug-10, Volume: 308, Issue:3

    Topics: Anesthesia; Animals; Carbolines; Electrophysiology; Harmaline; Harmine; Imidazoline Receptors; Locus Coeruleus; Male; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Drug; Vagotomy

2001
Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake.
    Journal of neurochemistry, 2004, Volume: 89, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Carbolines; Cell Line; Cell Survival; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Harmaline; Harmine; Humans; Inhibitory Concentration 50; Kidney; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Methylation; Nerve Tissue Proteins; Parkinson Disease, Secondary; Piperazines

2004
A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions.
    Drug testing and analysis, 2017, Volume: 9, Issue:4

    Topics: Alkaloids; Carbolines; Electrophoresis, Capillary; Harmaline; Harmine; Limit of Detection; Monoamine Oxidase Inhibitors; Peganum; Plant Extracts; Psychotropic Drugs; Seeds; Time Factors

2017
Mechanism-based pharmacokinetics-pharmacodynamics studies of harmine and harmaline on neurotransmitters regulatory effects in healthy rats: Challenge on monoamine oxidase and acetylcholinesterase inhibition.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 62

    Topics: Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Brain; Carbolines; Cholinesterase Inhibitors; Chromatography, Liquid; Endothelial Cells; Harmaline; Harmine; Humans; Male; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Tandem Mass Spectrometry

2019
Light-induced full aromatization and hydroxylation of 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole alkaloid: Oxygen partial pressure as a key modulator of the photoproducts distribution.
    Journal of photochemistry and photobiology. B, Biology, 2019, Volume: 199

    Topics: Alkaloids; Carbolines; Harmaline; Harmine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylation; Indoles; Light; Multivariate Analysis; Oxygen; Partial Pressure; Photochemical Processes; Reactive Oxygen Species; Singlet Oxygen; Structure-Activity Relationship

2019
UV-light-driven photooxidation of harmaline catalyzed by riboflavin: Product characterization and mechanisms.
    Fitoterapia, 2021, Volume: 155

    Topics: Carbolines; Cell Line, Tumor; Harmaline; Harmine; Humans; Molecular Structure; Neuroprotective Agents; Oxidation-Reduction; Riboflavin; Ultraviolet Rays

2021