Compounds > norharman
Page last updated: 2024-08-24

norharman and 9-(4'-aminophenyl)-9h-pyrido(3,4-b)indole

norharman has been researched along with 9-(4'-aminophenyl)-9h-pyrido(3,4-b)indole in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawanishi, S; Murata, M; Ohnishi, S; Oikawa, S; Takamura, T; Totsuka, Y; Wakabayashi, K1
Hisada, S; Ishihara, J; Kawamori, T; Mitsumori, K; Sugimura, T; Totsuka, Y; Wakabayashi, K1
Hada, N; Maeda, Y; Matsuoka, A; Ohe, T; Takata, T; Tanaka, N; Totsuka, Y; Wakabayashi, K1
Naga, T; Totsuka, Y; Wakabayashi, K; Yoshimura, S1
Kataoka, H; Sugimura, T; Takamura-Enya, T; Totsuka, Y; Wakabayashi, K1
Kawahara, N; Nishigaki, R; Sugimura, T; Takamura-Enya, T; Totsuka, Y; Wakabayashi, K1
Masumura, K; Nohmi, T; Totsuka, Y; Wakabayashi, K1
Kawamori, T; Kitamura, T; Shibata, H; Sugimura, T; Totsuka, Y; Uchiya, N; Wakabayashi, K1
Nishigaki, R; Sugimura, T; Takamura-Enya, T; Totsuka, Y; Wakabayashi, K1
Akasu, T; Goto, S; Kataoka, H; Nishigaki, R; Sugimura, T; Totsuka, Y; Ushiyama, H; Wakabayashi, K; Watanabe, T1

Other Studies

10 other study(ies) available for norharman and 9-(4'-aminophenyl)-9h-pyrido(3,4-b)indole

ArticleYear
Oxidative DNA damage by an N-hydroxy metabolite of the mutagenic compound formed from norharman and aniline.
    Mutation research, 2001, Jul-25, Volume: 494, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aniline Compounds; Carbolines; Copper; Deoxyguanosine; DNA; DNA Damage; Harmine; Indoles; Models, Chemical; Mutagens; NAD; Oxidation-Reduction; Pyridines

2001
Testicular toxicity in F344 rats by aminophenylnorharman, formed from norharman and aniline.
    Toxicology and applied pharmacology, 2001, Sep-01, Volume: 175, Issue:2

    Topics: Administration, Oral; Aniline Compounds; Animals; Body Weight; Carbolines; Carcinogens; Follicle Stimulating Hormone; Harmine; Indoles; Luteinizing Hormone; Male; Mutagens; Organ Size; Pyridines; Rats; Rats, Inbred F344; Seminiferous Tubules; Testis

2001
Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline.
    Mutation research, 2002, Mar-25, Volume: 515, Issue:1-2

    Topics: Aniline Compounds; Animals; Carbolines; Carcinogens; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Adducts; Harmine; Indoles; Lung; Mitomycins; Mutagens; Pyridines; Salmonella typhimurium; Sister Chromatid Exchange

2002
Maternal and developmental toxicity in mice by aminophenylnorharman, formed from norharman and aniline.
    Human & experimental toxicology, 2002, Volume: 21, Issue:3

    Topics: Aniline Compounds; Animals; Carbolines; Cleft Palate; Female; Fetus; Harmine; Humans; Indoles; Liver; Male; Maternal Exposure; Mice; Mice, Inbred ICR; Mutagens; Pregnancy; Pyridines

2002
In vitro and in vivo formation of aminophenylnorharman from norharman and aniline.
    Mutation research, 2002, Sep-30, Volume: 506-507

    Topics: Aniline Compounds; Animals; Carbolines; Carcinogens; Chromatography, Gas; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Harmine; In Vitro Techniques; Indoles; Male; Microsomes, Liver; Proadifen; Pyridines; Rats; Rats, Inbred F344

2002
Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline.
    Chemical research in toxicology, 2002, Volume: 15, Issue:10

    Topics: Aniline Compounds; Animals; Carbolines; Colon; DNA Adducts; Drug Interactions; Harmine; Indoles; Liver; Male; Mutagens; Pyridines; Rats; Rats, Inbred F344; Tissue Distribution

2002
Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.
    Carcinogenesis, 2003, Volume: 24, Issue:12

    Topics: Aniline Compounds; Animals; Carbolines; Carcinogens; Colon; Colonic Neoplasms; CpG Islands; DNA Mutational Analysis; Dose-Response Relationship, Drug; Gene Deletion; Harmine; Humans; Indoles; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Chemical; Mucous Membrane; Mutagens; Mutation; Pyridines; Time Factors

2003
Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats.
    Carcinogenesis, 2004, Volume: 25, Issue:10

    Topics: Adenocarcinoma; Aniline Compounds; Animals; beta Catenin; Carbolines; Carcinoma, Hepatocellular; Colon; Colonic Neoplasms; Cytoskeletal Proteins; Female; Genes, APC; Genes, ras; Harmine; Indoles; Leukemia; Liver; Liver Neoplasms; Male; Mutagens; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pyridines; Rats; Rats, Inbred F344; Thyroid Neoplasms; Trans-Activators

2004
Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline.
    Mutation research, 2004, Aug-08, Volume: 562, Issue:1-2

    Topics: Aniline Compounds; Carbolines; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Harmine; Indoles; Mutagens; Pyridines; Spectrophotometry, Ultraviolet

2004
Detection of aminophenylnorharman, a possible endogenous mutagenic and carcinogenic compound, in human urine samples.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:1

    Topics: Adult; Aniline Compounds; Carbolines; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Harmine; Humans; Indoles; Japan; Male; Middle Aged; Mutagens; Pyridines; Smoking

2007