Compounds > norharman
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norharman and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

norharman has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Good, AC; Peterson, SJ; Richards, WG1
Beach, JW; Collins, MA; Gearhart, DA; Hwang, YI; Neafsey, EJ; Schwarz, J; Storch, A1
Brittebo, EB; Fredriksson, A; Ostergren, A1
Guillén, H; Herraiz, T1
Herraiz, T1

Other Studies

5 other study(ies) available for norharman and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
    Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20

    Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship

1993
Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake.
    Journal of neurochemistry, 2004, Volume: 89, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Carbolines; Cell Line; Cell Survival; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Harmaline; Harmine; Humans; Inhibitory Concentration 50; Kidney; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Methylation; Nerve Tissue Proteins; Parkinson Disease, Secondary; Piperazines

2004
Norharman-induced motoric impairment in mice: neurodegeneration and glial activation in substantia nigra.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Carbolines; Caspase 3; Caspases; Disease Models, Animal; Fluoresceins; Gait Disorders, Neurologic; Glial Fibrillary Acidic Protein; Gliosis; Harmine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mitochondria; Motor Activity; Nerve Degeneration; Neuroglia; Neurons; Neurotoxins; Organic Chemicals; Parkinsonian Disorders; PC12 Cells; Rats; Substantia Nigra

2006
Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Antioxidants; Carbolines; Chromatography, High Pressure Liquid; Harmine; Humans; Indazoles; Mass Spectrometry; Methylene Blue; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Selegiline

2011
Evaluation of the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to toxic pyridinium cations by monoamine oxidase (MAO) enzymes and its use to search for new MAO inhibitors and protective agents.
    Journal of enzyme inhibition and medicinal chemistry, 2012, Volume: 27, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Carbolines; Chromatography, High Pressure Liquid; Clorgyline; Enzyme Assays; Harmine; Humans; Indazoles; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Nicotiana; Oxidation-Reduction; Pyridinium Compounds; Recombinant Proteins; Selegiline; Smoke; Vitamin K 3

2012