Page last updated: 2024-08-23

norgestimate and levonorgestrel

norgestimate has been researched along with levonorgestrel in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's17 (47.22)18.2507
2000's13 (36.11)29.6817
2010's3 (8.33)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Dain, MP; Janaud, A; Rouffy, J; Upmalis, D1
Chapdelaine, A; London, RS; Olson, W; Smith, J; Upmalis, D1
Hahn, DW; McGuire, JL; Phillips, A1
Flor, S; Hahn, DW; Kafrissen, ME; McGuire, JL; Phillips, A; Tolman, EL1
Roy, S; Stanczyk, FZ1
Rabe, T; Runnebaum, B1
Hahn, DW; Hetyei, NS; Killinger, J; McGuire, JL; Phillips, A1
Donnez, J; Grandjean, P; Lavenne, E; Schlit, AF1
Fritzemeier, KH; Hegele-Hartung, C; Krattenmacher, R; Kuhnz, W1
Blode, H; Kuhnz, W; Mahler, M1
Beier, S; Kuhnz, W1
Creatsas, G; Serfaty, D; Verougstraete, A; Wildemeersch, D1
Bruppacher, R; Heinemann, LA; Lewis, MA; MacRae, KD; Spitzer, WO1
Schwingl, PJ; Shelton, J1
Bloemenkamp, KW; Helmerhorst, FM; Rosendaal, FR; Vandenbroucke, JP1
Hamulyak, K; Heijnen, P; Hemker, HC; Nicolaes, GA; Rosing, J; Tans, G; Thomassen, MC; van der Ploeg, PM; van Oerle, R1
Duda, M; Edom, RW; Huang, M; Juzwin, S; Tegegne, G; Tischio, JP; Wong, FA1
Cusson, J; Heinemann, L; Lewis, M; Rainville, B; Spitzer, WO; Suissa, S1
Abrams, LS; Lasseter, KC; Natarajan, J; Skee, DM; Wong, FA1
Milsom, I; Odlind, V; Persson, I; Victor, A1
Creinin, MD; Eder, SE; Godwin, AJ; Lippman, JS; Olson, W1
Taneepanichskul, S; Tantbirojn, P1
Abrams, LS; Allen, JG; Creasy, GW; Hammond, GL; Natarajan, J; Siiteri, PK1
Baerwald, AR; Olatunbosun, OA; Pierson, RA1
Birtch, RL; Olatunbosun, OA; Pierson, RA1
Jick, H; Jick, SS; Kaye, JA; Russmann, S1
Jick, H; Jick, SS1
Burrows, M; Peters, C1
Bacquet, A; Balaguer, P; Paris, F; Rabeolina, F; Sultan, C1
Tan, JK1
Buono, MJ; Martin, JG1
Cecchini, R; Gold, MA; Land, SR; Murray, PJ; Sucato, GS1
Lidegaard, O; Løkkegaard, E; Nielsen, LH; Skovlund, CW1
Curtis, KM; Dragoman, MV; Gaffield, ME; Tepper, NK1
Del Savio, MC; Facchinetti, F; Grandi, G1

Reviews

5 review(s) available for norgestimate and levonorgestrel

ArticleYear
Pharmacologic and pharmacokinetic characteristics of norgestimate and its metabolites.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:6 Pt 2

    Topics: Animals; Biotransformation; Contraceptives, Oral; Drug Combinations; Female; Humans; Levonorgestrel; Molecular Structure; Norgestrel; Oximes

1990
Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids.
    Contraception, 1990, Volume: 42, Issue:1

    Topics: Animals; Contraceptives, Oral, Combined; Desogestrel; Female; Humans; Levonorgestrel; Norethindrone; Norgestrel; Norpregnenes

1990
New developments in hormonal therapy for acne.
    Skin therapy letter, 2007, Volume: 12, Issue:7

    Topics: Acne Vulgaris; Androstenes; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Norgestrel

2007
Nonoral combined hormonal contraceptives and thromboembolism: a systematic review.
    Contraception, 2017, Volume: 95, Issue:2

    Topics: Administration, Cutaneous; Adolescent; Adult; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Levonorgestrel; Norgestrel; Progestins; Risk Factors; Thromboembolism; Venous Thromboembolism; Young Adult

2017
The paradigm of norgestimate: a third-generation testosterone-derivative progestin with a peripheral anti-androgenic activity and the lowest risk of venous thromboembolism.
    Expert review of clinical pharmacology, 2021, Volume: 14, Issue:2

    Topics: Animals; Contraceptive Agents, Hormonal; Female; Humans; Levonorgestrel; Norgestrel; Risk; Venous Thromboembolism

2021

Trials

13 trial(s) available for norgestimate and levonorgestrel

ArticleYear
A comparison study of lipid and androgen metabolism with triphasic oral contraceptive formulations containing norgestimate or levonorgestrel.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1992, Volume: 156

    Topics: Adolescent; Adult; Androgens; Blood Pressure; Body Weight; Contraceptives, Oral, Combined; Female; Humans; Levonorgestrel; Lipids; Norgestrel

1992
Comparative contraceptive efficacy and mechanism of action of the norgestimate-containing triphasic oral contraceptive.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1992, Volume: 156

    Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Estradiol; Female; Follicle Stimulating Hormone; Humans; Levonorgestrel; Luteinizing Hormone; Norgestrel; Ovulation; Progesterone; Sex Hormone-Binding Globulin

1992
Large increase in plasmatic 11-dehydro-TxB2 levels due to oral contraceptives.
    Contraception, 1995, Volume: 51, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Analysis of Variance; Contraceptives, Oral; Ethinyl Estradiol; Factor VII; Factor VIII; Female; Fibrinogen; Humans; Levonorgestrel; Norethindrone; Norgestrel; Prothrombin; Thromboxane B2

1995
Systemic availability of levonorgestrel after single oral administration of a norgestimate-containing combination oral contraceptive to 12 young women.
    Contraception, 1994, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Biological Availability; Contraceptives, Oral, Combined; Ethinyl Estradiol; Female; Half-Life; Humans; Levonorgestrel; Norgestrel

1994
An open label, randomized study to evaluate the effects of seven monophasic oral contraceptive regimens on hemostatic variables. Outline of the protocol. Oral Contraceptive and Hemostasis Study Group.
    Contraception, 1999, Volume: 59, Issue:6

    Topics: Blood Coagulation; Contraceptives, Oral; Desogestrel; Ethinyl Estradiol; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Hemostasis; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Peptide Fragments; Prothrombin; Thrombin; Venous Thrombosis

1999
Multiple-dose pharmacokinetics of a contraceptive patch in healthy women participants.
    Contraception, 2001, Volume: 64, Issue:5

    Topics: Administration, Cutaneous; Adult; Analysis of Variance; Contraceptive Agents, Female; Drug Administration Schedule; Drug Combinations; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Middle Aged; Norgestrel; Oximes; Time Factors

2001
The effect of extending the pill-free interval on follicular activity: triphasic norgestimate/35 micro g ethinyl estradiol versus monophasic levonorgestrel/20 micro g ethinyl estradiol.
    Contraception, 2002, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Contraceptives, Oral, Synthetic; Estradiol; Ethinyl Estradiol; Female; Follicle Stimulating Hormone; Humans; Levonorgestrel; Luteinizing Hormone; Norgestrel; Ovarian Follicle; Patient Compliance; Progesterone

2002
Clinical comparative study of oral contraceptives containing 30 microg ethinylestradiol/150 microg levonorgestrel, and 35 microg ethinylestradiol/250 microg norgestimate in Thai women.
    Contraception, 2002, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Blood Pressure; Body Weight; Contraceptives, Oral; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Menstrual Cycle; Norgestrel; Thailand; Uterine Hemorrhage

2002
Serum distribution of the major metabolites of norgestimate in relation to its pharmacological properties.
    Contraception, 2003, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Drug Combinations; Ethinyl Estradiol; Ethisterone; Female; Humans; Levonorgestrel; Norgestrel; Oximes; Serum Albumin; Sex Hormone-Binding Globulin; Testosterone

2003
Ovarian follicular development is initiated during the hormone-free interval of oral contraceptive use.
    Contraception, 2004, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Desogestrel; Drug Administration Schedule; Endometrium; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Norgestrel; Ovarian Follicle; Treatment Outcome; Ultrasonography

2004
Ovarian follicular dynamics during conventional vs. continuous oral contraceptive use.
    Contraception, 2006, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Drug Administration Schedule; Female; Humans; Levonorgestrel; Menstrual Cycle; Norgestrel; Ovarian Follicle; Time Factors; Ultrasonography

2006
Androgenicity of the progestin in oral contraceptives does not affect maximal leg strength.
    Contraception, 2006, Volume: 74, Issue:6

    Topics: Adult; Androgens; Contraceptives, Oral, Combined; Ethinyl Estradiol; Exercise; Female; Humans; Leg; Levonorgestrel; Muscle Strength; Norgestrel; Progesterone Congeners; Progestins; Sports

2006
Oral contraceptives elevate core temperature and heart rate during exercise in the heat.
    Clinical physiology (Oxford, England), 1997, Volume: 17, Issue:4

    Topics: Adult; Body Temperature; Body Temperature Regulation; Contraceptives, Oral; Desogestrel; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Exercise; Female; Heart Rate; Hot Temperature; Humans; Levonorgestrel; Luteal Phase; Mestranol; Norethindrone; Norgestrel; Skin Temperature

1997

Other Studies

18 other study(ies) available for norgestimate and levonorgestrel

ArticleYear
Relative binding affinity of norgestimate and other progestins for human sex hormone-binding globulin.
    Steroids, 1990, Volume: 55, Issue:8

    Topics: Binding, Competitive; Desogestrel; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Progesterone; Progestins; Sex Hormone-Binding Globulin; Testosterone

1990
New progestogens in oral contraceptives.
    American journal of obstetrics and gynecology, 1987, Volume: 157, Issue:4 Pt 2

    Topics: Contraceptives, Oral, Combined; Desogestrel; Ethinyl Estradiol; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Levonorgestrel; Lipids; Lipoproteins; Norgestrel; Norpregnenes; Progesterone Congeners

1987
The affinity of norgestimate for uterine progestogen receptors and its direct action on the uterus.
    Contraception, 1985, Volume: 32, Issue:3

    Topics: Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Endometrium; Female; Levonorgestrel; Norgestrel; Progesterone; Rabbits; Receptors, Progesterone; Uterus

1985
Comparative progestational activity of norgestimate, levonorgestrel-oxime and levonorgestrel in the rat and binding of these compounds to the progesterone receptor.
    Contraception, 1995, Volume: 51, Issue:2

    Topics: Animals; Drug Combinations; Female; Humans; Levonorgestrel; Norgestrel; Oximes; Pregnancy; Pregnancy Maintenance; Progesterone; Rabbits; Rats; Rats, Wistar; Receptors, Progesterone

1995
Comparative progestational and androgenic activity of norgestimate and levonorgestrel in the rat.
    Contraception, 1994, Volume: 49, Issue:3

    Topics: Androgens; Animals; Female; Kinetics; Levonorgestrel; Male; Norgestrel; Orchiectomy; Organ Size; Pregnancy; Pregnancy Maintenance; Progesterone Congeners; Prostate; Rats; Seminal Vesicles

1994
European Society of Contraception oral contraceptives survey update: birth control methods in "Europe of the 12".
    International journal of fertility and menopausal studies, 1995, Volume: 40 Suppl 2

    Topics: Adult; Aging; Cardiovascular Diseases; Contraception; Contraceptives, Oral; Data Collection; Desogestrel; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Estradiol Congeners; Ethinyl Estradiol; Europe; Female; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Progesterone; Progesterone Congeners; Risk Factors; Smoking; Surveys and Questionnaires

1995
The increased risk of venous thromboembolism and the use of third generation progestagens: role of bias in observational research. The Transnational Research Group on Oral Contraceptives and the Health of Young Women.
    Contraception, 1996, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Bias; Contraceptives, Oral, Synthetic; Desogestrel; Female; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Odds Ratio; Progesterone Congeners; Risk Factors; Thromboembolism

1996
Modeled estimates of myocardial infarction and venous thromboembolic disease in users of second and third generation oral contraceptives.
    Contraception, 1997, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Age Factors; Cohort Studies; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Desogestrel; Female; Humans; Incidence; Levonorgestrel; Myocardial Infarction; Norethindrone; Norgestrel; Risk Factors; Thrombophlebitis; United States

1997
Risk of oral contraceptives and recency of market introduction.
    Contraception, 1997, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Contraceptives, Oral, Synthetic; Desogestrel; Female; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Odds Ratio; Time Factors

1997
Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second- and third-generation oral contraceptives.
    British journal of haematology, 1997, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Aged; Contraceptives, Oral, Combined; Desogestrel; Factor V; Female; Hemostasis; Heterozygote; Humans; Levonorgestrel; Male; Middle Aged; Norgestrel; Norpregnenes; Protein C; Thrombin; Thrombophlebitis

1997
Determination of norgestimate and its metabolites in human serum using high-performance liquid chromatography with tandem mass spectrometric detection.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Nov-12, Volume: 734, Issue:2

    Topics: Chromatography, High Pressure Liquid; Contraceptives, Oral, Synthetic; Drug Combinations; Drug Stability; Female; Humans; Levonorgestrel; Mass Spectrometry; Molecular Structure; Norgestrel; Oximes; Quality Control; Reproducibility of Results; Sensitivity and Specificity

1999
Recurrent use of newer oral contraceptives and the risk of venous thromboembolism.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:4

    Topics: Adult; Body Mass Index; Case-Control Studies; Contraceptives, Oral, Synthetic; Desogestrel; Estrogens; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Logistic Models; Norgestrel; Norpregnenes; Risk Factors; Venous Thrombosis

2000
Can changes in sex hormone binding globulin predict the risk of venous thromboembolism with combined oral contraceptive pills?
    Acta obstetricia et gynecologica Scandinavica, 2002, Volume: 81, Issue:6

    Topics: Biomarkers; Contraceptives, Oral, Combined; Cyproterone Acetate; Desogestrel; Female; Humans; Levonorgestrel; Norgestrel; Norpregnenes; Predictive Value of Tests; Risk Factors; Sex Hormone-Binding Globulin; Venous Thrombosis

2002
Risk of nonfatal venous thromboembolism with oral contraceptives containing norgestimate or desogestrel compared with oral contraceptives containing levonorgestrel.
    Contraception, 2006, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Case-Control Studies; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Databases, Factual; Desogestrel; Female; Humans; Levonorgestrel; Longitudinal Studies; Norgestrel; Odds Ratio; Risk Factors; Thromboembolism

2006
Cerebral venous sinus thrombosis in users of four hormonal contraceptives: levonorgestrel-containing oral contraceptives, norgestimate-containing oral contraceptives, desogestrel-containing oral contraceptives and the contraceptive patch.
    Contraception, 2006, Volume: 74, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Cohort Studies; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Desogestrel; Female; Humans; Intracranial Thrombosis; Levonorgestrel; Norgestrel; Risk; Sinus Thrombosis, Intracranial

2006
Antiandrogenic activity of norgestimate in a human androgen-dependent stable-transfected cell line.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2007, Volume: 23, Issue:4

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Combinations; Humans; Levonorgestrel; Norgestrel; Oximes; Protein Binding; Receptors, Androgen; Time Factors; Transfection

2007
Adolescents' experiences using the contraceptive patch versus pills.
    Journal of pediatric and adolescent gynecology, 2011, Volume: 24, Issue:4

    Topics: Adolescent; Affect; Contraceptive Agents, Female; Contraceptives, Oral; Estrogens; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Longitudinal Studies; Menstruation; Norgestrel; Patient Satisfaction; Prospective Studies; Quality of Life; Surveys and Questionnaires; Transdermal Patch; Young Adult

2011
Venous thrombosis in users of non-oral hormonal contraception: follow-up study, Denmark 2001-10.
    BMJ (Clinical research ed.), 2012, May-10, Volume: 344

    Topics: Adolescent; Adult; Anticoagulants; Contraceptive Agents, Female; Contraceptive Devices, Female; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Denmark; Drug Implants; Epidemiologic Methods; Female; Humans; Levonorgestrel; Middle Aged; Norgestrel; Transdermal Patch; Venous Thrombosis; Young Adult

2012