norfluoxetine and dextromethorphan

norfluoxetine has been researched along with dextromethorphan in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	3 (60.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Cheung, SW; Joffe, RT; Otton, SV; Sellers, EM; Wu, D	1
Albano, D; Amchin, J; Ereshefsky, L; Klockowski, PM; Taylor, K; Zarycranski, W	1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA	1
Davis, C; Foti, RS; Isoherranen, N; Kunze, KL; Lutz, JD; Sager, JE	1

Trials

1 trial(s) available for norfluoxetine and dextromethorphan

Article	Year
Effect of venlafaxine versus fluoxetine on metabolism of dextromethorphan, a CYP2D6 probe. Journal of clinical pharmacology, 2001, Volume: 41, Issue:4 Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Cyclohexanols; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Drug Interactions; Female; Fluoxetine; Humans; Male; Metabolic Clearance Rate; Phenotype; Selective Serotonin Reuptake Inhibitors; Time Factors; Urinalysis; Venlafaxine Hydrochloride	2001

Article

Year

Effect of venlafaxine versus fluoxetine on metabolism of dextromethorphan, a CYP2D6 probe.

Journal of clinical pharmacology, 2001, Volume: 41, Issue:4

Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Cyclohexanols; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Drug Interactions; Female; Fluoxetine; Humans; Male; Metabolic Clearance Rate; Phenotype; Selective Serotonin Reuptake Inhibitors; Time Factors; Urinalysis; Venlafaxine Hydrochloride

2001

Other Studies

4 other study(ies) available for norfluoxetine and dextromethorphan

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Inhibition by fluoxetine of cytochrome P450 2D6 activity. Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:4 Topics: Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Fluoxetine; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Multiple Sclerosis; Oxidation-Reduction; Oxycodone; Phenotype; Selective Serotonin Reuptake Inhibitors	1993
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8 Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol	2007
Fluoxetine- and norfluoxetine-mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19, and CYP3A4. Clinical pharmacology and therapeutics, 2014, Volume: 95, Issue:6 Topics: Adult; Antidepressive Agents, Second-Generation; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dextromethorphan; Drug Interactions; Female; Fluoxetine; Half-Life; Hepatocytes; Humans; Lovastatin; Male; Midazolam; Models, Statistical; Omeprazole; Stereoisomerism	2014