norfloxacin and sparfloxacin

norfloxacin has been researched along with sparfloxacin in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.69)	18.7374
1990's	13 (22.03)	18.2507
2000's	32 (54.24)	29.6817
2010's	13 (22.03)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG	1
Dever, JA; Domagala, JM; Gage, JW; Gracheck, SJ; Renau, TE; Sanchez, JP; Shapiro, MA	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Cai, SH; Hasegawa, T; Kitaichi, K; Nadai, M; Takagi, K; Tatsumi, Y; Wang, L; Yoshizumi, H; Zhao, YL	1
Baroni, M; Cecchetti, V; Cianchetta, G; Cruciani, G; Mannhold, R	1
Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bachand, B; Barnes, MH; Bethell, R; Brown, NC; Butler, MM; Cadilhac, C; Charron, S; Comstock, J; Dix, EJ; Foster, KA; Holm, KA; LaMarr, WA; Lamothe, S; Long, ZY; Manikowski, A; Motorina, I; Storer, R; Tarantino, PM; Wright, GE; Xu, WC; Zhi, C	1
Arpin, C; Ba, BB; Caignard, DH; Forfar-Bares, I; Grellet, J; Guillon, J; Jarry, C; Moreau, S; Quentin, C; Vidaillac, C	1
Allison, BD; Goldschmidt, RM; Gomez, L; Grice, CA; Hack, MD; Jones, TK; Morrow, BJ; Motley, ST; Santillán, A; Schwarz, KL; Shaw, KJ; Shinde, S; Tang, L; Venkatesan, H; Wiener, JJ	1
Cattoir, V; Mazel, D; Nordmann, P; Poirel, L; Soussy, CJ	1
Cattoir, V; Nordmann, P; Poirel, L	1
Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K	1
Morgan-Linnell, SK; Zechiedrich, L	1
Cattoir, V; Espinal, P; Nordmann, P; Poirel, L; Silva-Sanchez, J	1
Hiramatsu, K; Kikuchi, K; Ohtsuka, M; Ono, Y; Sasaki, T; Shimizu, K; Takahashi, N	2
Bremont, S; Charavay, F; Courvalin, P; Goarant, C; Le Hello, S; O'Connor, O; Page, S; Vernel-Pauillac, F	1
Chevalier, J; Davin-Regli, A; Dupont, M; Lavigne, JP; Pagès, JM; Sotto, A; Tran, QT	1
Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE	1
Agrawal, YK; Manna, K	1
Chhasatia, MR; Gandhi, DS; Patel, MN	1
Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J	1
Avdeef, A; Sun, N; Tam, KY; Tsinman, O	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Blango, MG; Mulvey, MA	1
Avdeef, A; Tam, KY	1
Gotoh, N; Hayashi, N; Okuda, J; Wakahara, Y	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Akylbekov, N; Bulatova, A; Burilov, A; Chugunova, E; Dobrynin, A; Gavrilov, N; Kulik, N; Syakaev, V; Voloshina, A; Zobov, V	1
Zhang, B	1
Ciura, K; Fallarero, A; Fedorowicz, J; Gilbert-Girard, S; Konopacka, A; Lejnowski, D; Morawska, M; Sączewski, J; Savijoki, K; Skok, Ž; Tomašič, T; Waleron, K	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Cobbs, CG; Smith, KR	1
Almodovar, E; Burns, JJ; Qadri, SM; Rabea, N; Ueno, Y	1
Inoue, M; Kojima, T; Mitsuhashi, S; Yoshida, S	1
Kashimoto, S; Kojima, T; Kouno, K; Kurobe, N; Minami, A; Nakamura, S; Nakata, K; Ohue, T; Sakaguchi, Y; Yoshida, H	1
el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF	1
Phillips, I; Power, EG	1
Asaoka, T; Imamori, K; Maebashi, K; Matsuda, H; Matsumoto, M; Tahara, Y	1
Chilima, BZ; Okazawa, Y; Tanno, K; Tosaka, M; Yamane, N	1
Chambers, HF; Hackbarth, CJ; Kocagöz, T; Nikaido, H; Rosenberg, EY; Unsal, I	1
Fabian, I; Gruss, T; Kletter, Y; Shalit, I; Weiss, K	1
Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H	1
Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H	1
Bouquet, S; Couet, W; de Boer, AG; de Lange, EC; Delon, A; Marchand, S; van den Berg, D; van der Sandt, IC	1
Andrews, JM; Boswell, FJ; Wise, R	1
Fukuda, H; Kawamura, Y	1
Katouno, Y; Kobayashi, Y; Sugita, K; Uchida, H	1
Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T	1
Ono, C; Tanaka, M	1
Cushnie, TP; Lamb, AJ	1
Inoue, M; Ito, H; Oyamada, Y; Yamagishi, JI	1
Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z	1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M	1
Adam, E; Baitiche, M; Chevalier, J; Mahamoud, A; Pagès, JM	1
Betlejewska-Kielak, K; Biernacka, J; Grudzień, M; Kłosińska-Szmurło, E; Mazurek, AP; Pluciński, FA	1

Reviews

2 review(s) available for norfloxacin and sparfloxacin

Article	Year
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. European journal of medicinal chemistry, 2019, Apr-15, Volume: 168 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019

Other Studies

57 other study(ies) available for norfloxacin and sparfloxacin

Article	Year
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1991
Structure-activity relationships of the quinolone antibacterials against mycobacteria: effect of structural changes at N-1 and C-7. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Anti-Bacterial Agents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mycobacterium; Spectrophotometry, Infrared; Structure-Activity Relationship	1996
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Possible involvement of P-glycoprotein in the biliary excretion of grepafloxacin. Clinical and experimental pharmacology & physiology, 2002, Volume: 29, Issue:3 Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biliary Tract; Doxorubicin; Drug Resistance, Neoplasm; Fluoroquinolones; Leukemia P388; Male; Mice; Piperazines; Quinolones; Rats; Rats, Wistar; Tumor Cells, Cultured	2002
Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach. Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12 Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Models, Molecular; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Quinolones; Staphylococcus aureus; Thermodynamics	2004
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus. Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors. Journal of medicinal chemistry, 2006, Feb-23, Volume: 49, Issue:4 Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; DNA Polymerase III; Drug Resistance, Bacterial; Gram-Positive Bacteria; Male; Mice; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors; Toxicity Tests, Acute; Uracil	2006
Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Culture Media; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Indicators and Reagents; Kinetics; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Norfloxacin; Omeprazole; Staphylococcus aureus; Structure-Activity Relationship	2007
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains. Bioorganic & medicinal chemistry letters, 2007, May-15, Volume: 17, Issue:10 Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Enzyme Inhibitors; Indazoles; Microbial Sensitivity Tests; Structure-Activity Relationship; Topoisomerase II Inhibitors	2007
Vibrio splendidus as the source of plasmid-mediated QnrS-like quinolone resistance determinants. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Open Reading Frames; Plasmids; Polymerase Chain Reaction; Quinolones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Vibrio	2007
Plasmid-mediated quinolone resistance determinant QnrB4 identified in France in an Enterobacter cloacae clinical isolate coexpressing a QnrS1 determinant. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacter cloacae; Escherichia coli; France; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Plasmids; Quinolones; Transformation, Genetic	2007
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents	2007
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: DNA Topoisomerases; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation	2007
ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Base Sequence; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Quinolones	2008
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Alleles; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Chromosomes, Bacterial; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Molecular Sequence Data; Sequence Homology, Amino Acid; Stenotrophomonas maltophilia	2008
Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Amino Acid Substitution; Base Sequence; DNA Gyrase; DNA Mutational Analysis; DNA Primers; DNA Probes; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Humans; Nucleic Acid Denaturation; Point Mutation; Polymerase Chain Reaction; Streptococcus pneumoniae; Thermodynamics	2008
Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Bacterial Proteins; beta-Lactamases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cefepime; Cephalosporinase; Cephalosporins; Drug Resistance, Bacterial; Enterobacter aerogenes; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests	2009
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif. Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6 Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei	2009
Microwave assisted synthesis of new indophenazine 1,3,5-trisubstruted pyrazoline derivatives of benzofuran and their antimicrobial activity. Bioorganic & medicinal chemistry letters, 2009, May-15, Volume: 19, Issue:10 Topics: Anti-Bacterial Agents; Benzofurans; Microbial Sensitivity Tests; Microwaves; Phenazines	2009
Emergence of quinolone-resistant Bordetella pertussis in Japan. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Anti-Bacterial Agents; Bordetella pertussis; Child; DNA Gyrase; Fluoroquinolones; Humans; Japan; Microbial Sensitivity Tests; Mutation; Nalidixic Acid; Quinolones	2009
Interaction of drug based binuclear mixed-ligand complexes with DNA. Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15 Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Ciprofloxacin; Cobalt; DNA, Bacterial; Ligands; Magnetic Resonance Spectroscopy; Magnetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; Spectrophotometry, Infrared; Structure-Activity Relationship; Temperature; Viscosity	2009
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents. Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines	2009
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistance, Bacterial; Endosomes; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred CBA; Microbial Sensitivity Tests; Recurrence; Urinary Bladder; Urinary Tract Infections; Urothelium	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Reduced expression of the vca0421 gene of Vibrio cholerae O1 results in innate resistance to ciprofloxacin. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Fluoroquinolones; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Vibrio cholerae O1	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and biological evaluation of novel structural hybrids of benzofuroxan derivatives and fluoroquinolones. European journal of medicinal chemistry, 2016, Jun-30, Volume: 116 Topics: Anti-Bacterial Agents; Bacteria; Benzoxazoles; Chemistry Techniques, Synthetic; Drug Design; Fluoroquinolones; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship	2016
Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents. European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Quinolones; Structure-Activity Relationship	2019
In vitro activity of sparfloxacin and three other fluoroquinolones against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:1 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Quinolones; Staphylococcus aureus; Staphylococcus epidermidis	1992
In vitro activity of sparfloxacin (CI-978), a new broad-spectrum fluoroquinolone. Chemotherapy, 1992, Volume: 38, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Microbial Sensitivity Tests; Norfloxacin; Quinolones	1992
Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:2 Topics: Anti-Infective Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Staphylococcal Infections; Staphylococcus aureus	1991
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:8 Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Lung Diseases; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Skin Diseases, Infectious; Urinary Tract Infections	1989
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity. The Journal of infectious diseases, 1995, Volume: 171, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease	1995
Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents. FEMS microbiology letters, 1993, Sep-15, Volume: 112, Issue:3 Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA-Directed DNA Polymerase; Enoxacin; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Gene Expression Regulation, Bacterial; Mutagenicity Tests; Nalidixic Acid; Naphthyridines; Norfloxacin; Quinolones; Salmonella typhimurium; SOS Response, Genetics; Species Specificity	1993
In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone. The Japanese journal of antibiotics, 1995, Volume: 48, Issue:12 Topics: Anti-Infective Agents; Azepines; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones	1995
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media]. Kekkaku : [Tuberculosis], 1996, Volume: 71, Issue:8 Topics: Anti-Infective Agents; Antitubercular Agents; Ciprofloxacin; Culture Media; Fluoroquinolones; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Quinolones	1996
Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:8 Topics: Anti-Infective Agents; Antitubercular Agents; Base Sequence; Cell Wall; Cephaloridine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Norfloxacin; Ofloxacin; Permeability; Quinolones	1996
Enhanced hematopoiesis in sublethally irradiated mice treated with various quinolones. European journal of haematology, 1997, Volume: 58, Issue:2 Topics: Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Ciprofloxacin; Cobalt Radioisotopes; Colony-Forming Units Assay; Culture Media, Conditioned; Fleroxacin; Fluoroquinolones; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cells; Hemoglobins; Interleukin-3; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Norfloxacin; Ofloxacin; Quinolones; Whole-Body Irradiation	1997
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer. The Journal of antimicrobial chemotherapy, 1997, Volume: 39 Suppl B Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Neoplasms; Norfloxacin; Ofloxacin; Quinolones	1997
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates. Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:2 Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin	2000
In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:2 Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cell Line; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Infusions, Intra-Arterial; Kidney; Mice; Mice, Inbred Strains; Mice, Knockout; Microdialysis; Norfloxacin; Pefloxacin; Recombinant Proteins; Rhodamine 123; Swine; Tissue Distribution; Transfection	2000
Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Norfloxacin; Quinolines; Quinolones; Streptococcus pneumoniae	2001
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins	2002
[Comparative in vitro activities of several antimicrobial agents against Helicobacter pylori]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6 Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ciprofloxacin; Clarithromycin; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Gastric Mucosa; Helicobacter pylori; Humans; Levofloxacin; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Penicillins; Stomach Ulcer	2002
Reliability of phototoxic tests of fluoroquinolones in vitro. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:5 Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays	2003
Binding characteristics of fluoroquinolones to synthetic levodopa melanin. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:8 Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol	2003
Assessment of the antibacterial activity of galangin against 4-quinolone resistant strains of Staphylococcus aureus. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2006, Volume: 13, Issue:3 Topics: 4-Quinolones; Anti-Bacterial Agents; DNA Topoisomerases; Drug Resistance, Bacterial; Flavonoids; Fluoroquinolones; Microbial Sensitivity Tests; Mutation; Norfloxacin; Plant Extracts; Staphylococcus aureus	2006
Topoisomerase mutations and efflux are associated with fluoroquinolone resistance in Enterococcus faecalis. Journal of medical microbiology, 2006, Volume: 55, Issue:Pt 10 Topics: Anti-Infective Agents; Bacterial Proteins; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Enterococcus faecalis; Fluoroquinolones; Membrane Transport Proteins; Microbial Sensitivity Tests; Norfloxacin; Point Mutation	2006
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography, 2007, Volume: 25, Issue:4 Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2007
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures	2009
An alkylaminoquinazoline restores antibiotic activity in Gram-negative resistant isolates. Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Membrane Transport Proteins; Microbial Sensitivity Tests; Nalidixic Acid; Norfloxacin; Quinazolines	2011
Experimental and theoretical studies on the molecular properties of ciprofloxacin, norfloxacin, pefloxacin, sparfloxacin, and gatifloxacin in determining bioavailability. Journal of biological physics, 2014, Volume: 40, Issue:4 Topics: Biological Availability; Buffers; Ciprofloxacin; Fluoroquinolones; Gastrointestinal Absorption; Gatifloxacin; Hydrogen-Ion Concentration; Models, Molecular; Molecular Conformation; Norfloxacin; Octanols; Pefloxacin; Phosphates; Solvents; Static Electricity; Thermodynamics	2014