Compounds > norfloxacin

norfloxacin and probenecid

norfloxacin has been researched along with probenecid in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (15.38)	18.7374
1990's	3 (23.08)	18.2507
2000's	2 (15.38)	29.6817
2010's	6 (46.15)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Cao, CX; Neu, HC; Silverstein, SC; Steinberg, TH	1
Dalton, H; Evans, T; Gruninger, RP; Kaplowitz, LG; Simpson, M; Vartivarian, S; Vishniavsky, N	1
Irikura, T; Kusajima, H; Shimada, J; Uchida, H; Ueda, Y; Yamaji, T	1
Jha, K; Roy, BK; Singh, RC	1
Chenel, M; Comets, E; Couet, W; Forsell, A; Lamarche, I; Marchand, S	1

Reviews

1 review(s) available for norfloxacin and probenecid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for norfloxacin and probenecid

Article	Year
Norfloxacin in the treatment of uncomplicated gonococcal infections. The American journal of medicine, 1987, Jun-26, Volume: 82, Issue:6B Topics: Adult; Aged; Ampicillin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Middle Aged; Norfloxacin; Probenecid; Random Allocation	1987

Other Studies

11 other study(ies) available for norfloxacin and probenecid

Article	Year
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
J774 macrophages secrete antibiotics via organic anion transporters. The Journal of infectious diseases, 1992, Volume: 165, Issue:2 Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Carrier Proteins; Cell Line; Cell Membrane Permeability; Fluorescent Dyes; Isoquinolines; Macrophages; Mice; Norfloxacin; Penicillin G; Probenecid	1992
Mechanism of renal excretion of AM-715, a new quinolonecarboxylic acid derivative, in rabbits, dogs, and humans. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1 Topics: Adult; Animals; Anti-Infective Agents; Creatinine; Dogs; Humans; Kidney; Male; Metabolic Clearance Rate; Nalidixic Acid; Norfloxacin; Probenecid; Rabbits; Species Specificity	1983
The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. Veterinary research communications, 1996, Volume: 20, Issue:5 Topics: Analysis of Variance; Animals; Drug Interactions; Endotoxins; Escherichia coli; Female; Fever; Goats; Lipopolysaccharides; Metabolic Clearance Rate; Models, Biological; Norfloxacin; Probenecid	1996
Norfloxacin blood-brain barrier transport in rats is not affected by probenecid coadministration. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:1 Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Drug Interactions; Male; Microdialysis; Norfloxacin; Probenecid; Rats; Rats, Sprague-Dawley	2006