norfloxacin and lomefloxacin

norfloxacin has been researched along with lomefloxacin in 100 studies

Research

Studies (100)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (10.00)	18.7374
1990's	31 (31.00)	18.2507
2000's	30 (30.00)	29.6817
2010's	28 (28.00)	24.3611
2020's	1 (1.00)	2.80

Authors

Authors	Studies
Bridges, AJ; Culbertson, TP; Domagala, JM; Gambino, L; Hagen, SE; Karrick, G; Porter, K; Sanchez, JP; Sesnie, JA; Spense, FG	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Antón-Fos, GM; Duart, MJ; Mut-Ronda, S; Salabert-Salvador, MT	1
Baroni, M; Cecchetti, V; Cianchetta, G; Cruciani, G; Mannhold, R	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K	1
Long, F; Rouquette-Loughlin, C; Shafer, WM; Yu, EW	1
Baliani, A; Barrett, MP; Chollet, C; Gilbert, IH; Wong, PE	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J	1
Hashida, Y; Konaka, R; Kourai, H; Maseda, H; Shirai, A	1
Avdeef, A; Sun, N; Tam, KY; Tsinman, O	1
Gozalbes, R; Pineda-Lucena, A	1
Bellman, K; Knegtel, RM; Settimo, L	1
Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E	1
Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R	1
Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E	1
Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW	1
Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Akylbekov, N; Bulatova, A; Burilov, A; Chugunova, E; Dobrynin, A; Gavrilov, N; Kulik, N; Syakaev, V; Voloshina, A; Zobov, V	1
Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E	1
Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW	1
Feng, LS; Liu, X; Pan, B; Zhang, GF; Zhang, S	1
Bai, L; Deng, JL; Gao, F; Lv, ZS; Wang, Y; Xu, Z; Zhang, F; Zhao, SJ	1
Guo, H	1
Ciura, K; Fallarero, A; Fedorowicz, J; Gilbert-Girard, S; Konopacka, A; Lejnowski, D; Morawska, M; Sączewski, J; Savijoki, K; Skok, Ž; Tomašič, T; Waleron, K	1
Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S	1
García, I; Pascual, A; Perea, EJ	1
Iravani, A	1
Hannan, A	1
Jones, RN	1
Forsgren, A; Hansson, C; Neringer, R; Ode, B	1
al-Shammary, FJ; el-Houfy, S; Shibl, AM; Tawfik, AF	1
Conejo, MC; García, I; Pascual, A; Perea, EJ	1
McDonald, PJ; Pruul, H	1
Borsa-Lebas, F; Dhib, M; Fillastre, JP; Humbert, G; Leroy, A; Moulin, B	1
Hall, MC; Piddock, LJ; Wise, R	1
Matsumoto, F; Morita, M; Takahashi, T	1
Bhattacharya, SS; Lal, HM; Lalitha, MK; Nisha, AK; Ramamoorthy, U	1
Clarke, AM; Zemcov, SJ	1
Greenwood, D; Kanematsu, M	1
Courvalin, P; Derlot, E; Poyart-Salmeron, C	1
Amano, M; Arakawa, S; Fujita, Y; Ishigami, J; Kamidono, S; Kanemasa, Y; Kumon, H; Ohmori, H; Suzuki, K; Tanaka, H	1
Weinstein, MP	1
Fernandes, PB; Swanson, RN	1
Nagayama, A; Nakao, T; Taen, H	1
Chin, NX; Neu, HC; Novelli, A	1
Edwards, R; Greenwood, D; Kanematsu, M	1
Hirose, T; Inoue, M; Ito, Y; Kato, H; Mitsuhashi, S; Okezaki, E	1
Cormican, MG; Jones, RN	1
Davidson, RJ; Drobot, GR; Hoban, DJ; Karlowsky, JA; Philips, R; Zhanel, GG	1
el-Kersh, TA; Ramadan, MA; Shibl, AM; Tawfik, AF	1
Fujita, H; Matsuo, I	1
Conly, JM; DuBois, J; Harding, GK; Martel, AY; Nicolle, LE; Shafran, SD	1
Riley, CM; Ross, DL; Takusagawa, F; Vander Velde, D	1
Benne, RA; Boon, TA; de Hond, HA; de Wit, MA; Havinga, WH; Hoepelman, IM; van Asbeck, FW; Verhoef, J; Visser, MR; Zwinkels, M	1
Hale, JA; Knapp, JS; Neal, SW; Rice, RJ; Whittington, WL; Wintersheid, K	1
Fukuda, S; Inatomi, M; Kanda, Y; Kiuchi, Y; Koide, R; Oguchi, K; Sato, H; Uchida, N	1
Ballesta, S; García, I; Pascual, A; Perea, EJ	1
Capron, MH; Guibert, J; Herman, H	1
Chignell, CF; Martínez, L	1
Albini, A; Fasani, E; Profumo, A	1
Fukuda, M; Sasaki, K; Yoshitake, Y	1
Jiménez de Anta, MT; Martín-Sánchez, AM; Ruiz, J; Tavío, MM; Vila, J	1
Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I	1
Castell, JV; Morlière, P; Ouédraogo, G; Santus, R	1
Bai, ZZ; Guan, DW; Zhang, QS	1
Iwatsu, M; Kanai, A; Sado, K; Tian, X	1
Schaeffer, AJ	1
Fukuda, H; Kawamura, Y	1
Monti, S; Sortino, S	1
Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T	1
Wos, M; Zünkler, BJ	1
Ono, C; Tanaka, M	1
Kawai, M; Mashima, Y; Mochizuki, H; Yamada, K; Yamada, M	1
Holzgrabe, U; Kiefer, W; Neugebauer, U; Popp, J; Schmitt, M; Szeghalmi, A	1
Abba, M; Donnelly, J; Hussain, B; Shervington, LA	1
Depta, JP; Pichler, WJ; Schmid, DA	1
Romero, IC; Saravia, NG; Walker, J	1
Ishikawa, K; Kawai, M; Mochizuki, H; Yamada, M	1
Ni, YN; Zhang, GW	1
Andreeva, I; Rafalsky, V; Rjabkova, E	1
Huang, CH; Zhang, H	1
Chen, X; Hua, H; Ji, C; Lin, X; Liu, Y; Tang, S; Yue, Z	1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M	1
Du, S; Kokot, S; Ni, Y	1
Gao, P; Li, YW; Mo, CH; Ruan, ZL; Tai, YP; Wang, QJ; Xu, JW; Zhang, Y	1
Alves, G; Falcão, A; Fortuna, A; Lino, C; Pena, A; Sousa, J	1
Du, J; Liu, B; Qin, X; Wang, H; Yan, H	1
Li, YW; Mo, CH; Su, QY; Tai, YP; Wang, JY; Wu, XL; Zhang, Y	1
Li, GR; Wang, YS; Yi, YN; Zhou, YZ; Zhu, HM	1
Jiang, W; Korshin, GV; Liu, C; Nanaboina, V	1
Cai, QH; Chen, GH; Chen, P; Guo, X; Meng, HL; Tian, YF	1
Cui, YF; He, JT; Qiao, XC; Su, SH; Yang, L	2
Dai, LL; Dai, XH; Li, N; Liu, HJ; Xue, YG; Yan, H	1

Reviews

9 review(s) available for norfloxacin and lomefloxacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
4-Quinolone derivatives and their activities against Gram positive pathogens. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: 4-Quinolones; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship	2018
Fluoroquinolone-isatin hybrids and their biological activities. European journal of medicinal chemistry, 2019, Jan-15, Volume: 162 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Antiviral Agents; Fluoroquinolones; Humans; Isatin; Structure-Activity Relationship	2019
Isatin derivatives and their anti-bacterial activities. European journal of medicinal chemistry, 2019, Feb-15, Volume: 164 Topics: Anti-Bacterial Agents; Bacteria; Humans; Isatin; Structure-Activity Relationship	2019
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019
Pharmacokinetics of quinolones in renal insufficiency. The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl B Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Glomerular Filtration Rate; Half-Life; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones	1990
The expanding role of fluoroquinolones. The American journal of medicine, 2002, Jul-08, Volume: 113 Suppl 1A Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections	2002
Quinolones for uncomplicated acute cystitis in women. The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3 Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic	2006
Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao. Environmental pollution (Barking, Essex : 1987), 2010, Volume: 158, Issue:7 Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Water Pollutants, Chemical; Water Supply	2010

Trials

6 trial(s) available for norfloxacin and lomefloxacin

Article	Year
Efficacy of lomefloxacin as compared to norfloxacin in the treatment of uncomplicated urinary tract infections in adults. The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Male; Middle Aged; Norfloxacin; Quinolones; Single-Blind Method; Treatment Outcome; Urinary Tract Infections	1992
Lomefloxacin versus norfloxacin in the treatment of uncomplicated urinary tract infections: three-day versus seven-day treatment. The South Swedish Lolex Study Group. Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Middle Aged; Norfloxacin; Quinolones; Sweden; Urinary Tract Infections	1992
[A comparative study on lomefloxacin and norfloxacin in the treatment of acute uncomplicated cystitis]. The Japanese journal of antibiotics, 1989, Volume: 42, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacteria; Child; Clinical Trials as Topic; Cystitis; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Humans; Middle Aged; Norfloxacin; Quinolones; Recurrence	1989
Treatment of acute uncomplicated urinary tract infections with 3 days of lomefloxacin compared with treatment with 3 days of norfloxacin. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Canada; Double-Blind Method; Female; Fluoroquinolones; Humans; Middle Aged; Norfloxacin; Prospective Studies; Quinolones; Treatment Outcome; Urinary Tract Infections	1993
Safety and efficacy of lomefloxacin versus norfloxacin in the treatment of complicated urinary tract infections. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Fluoroquinolones; Humans; Male; Middle Aged; Norfloxacin; Quinolones; Treatment Outcome; Urinary Tract Infections; Urine	1993
[Treatment of uncomplicated recurrent cystitis in women: lomefloxacin versus norfloxacin]. Contraception, fertilite, sexualite (1992), 1997, Volume: 25, Issue:1 Topics: Adult; Anti-Infective Agents; Cystitis; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Middle Aged; Norfloxacin; Patient Acceptance of Health Care; Quinolones; Recurrence; Urinary Tract Infections	1997

Other Studies

85 other study(ies) available for norfloxacin and lomefloxacin

Article	Year
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Alkylation; Aminoquinolines; Animals; Anti-Bacterial Agents; Bacterial Infections; Chemical Phenomena; Chemistry; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxyquinolines; Mice; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Pyrrolidines; Structure-Activity Relationship; Topoisomerase II Inhibitors	1991
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Search compounds with antimicrobial activity by applying molecular topology to selected quinolones. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Animals; Anti-Bacterial Agents; Bacteria; Discriminant Analysis; Drug Design; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolones	2003
Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach. Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12 Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Models, Molecular; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Quinolones; Staphylococcus aureus; Thermodynamics	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents	2007
Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Antiporters; ATP-Binding Cassette Transporters; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescence Polarization; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin	2008
Targeted delivery of compounds to Trypanosoma brucei using the melamine motif. Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6 Topics: Animals; Eflornithine; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents. Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines	2009
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12 Topics: Anti-Bacterial Agents; Bacterial Proteins; Cetylpyridinium; Disinfectants; Drug Resistance, Multiple, Bacterial; Membrane Proteins; Mutation; Norfloxacin; Quaternary Ammonium Compounds; Serratia marcescens	2009
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies. European journal of medicinal chemistry, 2014, Feb-12, Volume: 73 Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding	2014
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies	2014
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties. Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19 Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins	2014
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23 Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship	2014
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi	2015
Synthesis and biological evaluation of novel structural hybrids of benzofuroxan derivatives and fluoroquinolones. European journal of medicinal chemistry, 2016, Jun-30, Volume: 116 Topics: Anti-Bacterial Agents; Bacteria; Benzoxazoles; Chemistry Techniques, Synthetic; Drug Design; Fluoroquinolones; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship	2016
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors. Bioorganic & medicinal chemistry, 2016, 10-15, Volume: 24, Issue:20 Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship	2016
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21 Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei	2016
Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents. European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; HEK293 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quaternary Ammonium Compounds; Quinolones; Structure-Activity Relationship	2019
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors. European journal of medicinal chemistry, 2019, Oct-15, Volume: 180 Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine	2019
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease. European journal of medicinal chemistry, 2022, Jun-05, Volume: 236 Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate	2022
Comparative penetration of lomefloxacin and other quinolones into human phagocytes. The American journal of medicine, 1992, Apr-06, Volume: 92, Issue:4A Topics: Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Ciprofloxacin; Fluoroquinolones; Humans; In Vitro Techniques; Macrophages; Neutrophils; Norfloxacin; Ofloxacin; Quinolones	1992
Comparative in vitro activity of enoxacin and other fluoroquinolones against multi-resistant strains of Salmonella typhi. Current medical research and opinion, 1992, Volume: 12, Issue:9 Topics: Ampicillin; Anti-Infective Agents; Chloramphenicol; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Quinolones; Salmonella typhi; Species Specificity; Trimethoprim, Sulfamethoxazole Drug Combination; Typhoid Fever	1992
In vitro evaluation of E-4695, a new fluoro-naphthyridine. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:2 Topics: Anti-Bacterial Agents; Azetidines; Bacteria; Ciprofloxacin; Drug Evaluation, Preclinical; Enoxacin; Fleroxacin; Fluoroquinolones; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones	1992
Determination of lomefloxacin in biological fluids by high-performance liquid chromatography and a microbiological method. Journal of clinical pharmacy and therapeutics, 1991, Volume: 16, Issue:5 Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Mice; Microbiological Techniques; Norfloxacin; Quinolones	1991
Fluorometric and high-performance liquid chromatographic measurement of quinolone uptake by human neutrophils. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:11 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Fluorescence; Fluoroquinolones; Humans; Neutrophils; Norfloxacin; Ofloxacin; Quinolones	1991
Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils. The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:1 Topics: Anti-Infective Agents; Cell Division; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Humans; Neutrophils; Norfloxacin; Nucleic Acids; Phagocytosis; Pseudomonas aeruginosa; Quinolones; Tritium	1990
Mechanism of action of lomefloxacin. Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6 Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; DNA Topoisomerases, Type II; DNA, Bacterial; DNA, Superhelical; Fluoroquinolones; Kinetics; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Rec A Recombinases	1990
[Therapeutic drug monitoring of fluoroquinolone]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48 Suppl Topics: Anti-Infective Agents; Bile; Biological Assay; Biological Availability; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Naphthyridines; Norfloxacin; Ofloxacin; Quinolones; Sputum	1990
Susceptibility pattern of bacterial isolates to lomefloxacin. The Indian journal of medical research, 1990, Volume: 91 Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Nalidixic Acid; Norfloxacin; Quinolones	1990
Comparative in vitro activity of lomefloxacin, a new difluoroquinolone. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:2 Topics: Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ceftazidime; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gentamicins; Microbial Sensitivity Tests; Norfloxacin; Quinolones	1989
Studies on the emergence of resistance to lomefloxacin in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:8 Topics: Anti-Infective Agents; Ciprofloxacin; Cystitis; Drug Resistance, Microbial; Escherichia coli; Fluoroquinolones; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Biological; Norfloxacin; Quinolones	1989
Antibacterial and plasmid curing activity of lomefloxacin in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:12 Topics: Anti-Infective Agents; Enterobacteriaceae; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Plasmids; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus	1989
Comparative in vitro activity of lomefloxacin and other antimicrobials against 597 microorganisms causing bacteremia. Diagnostic microbiology and infectious disease, 1988, Volume: 11, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; Cefotaxime; Ceftazidime; Enoxacin; Fluoroquinolones; Humans; Imipenem; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Sepsis; Tobramycin	1988
Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:6 Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones	1988
In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Fleroxacin; Fluoroquinolones; Minocycline; Norfloxacin; Ofloxacin; Quinolones	1988
In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5 Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Magnesium; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Quinolines; Quinolones	1988
Laboratory assessment of lomefloxacin (SC-47111) in comparison with norfloxacin. The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:6 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Staphylococcus	1988
In vitro and in vivo activity of NY-198, a new difluorinated quinolone. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6 Topics: Animals; Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Male; Mice; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Oxazines; Pipemidic Acid; Quinolines; Quinolones	1987
Reevaluations of disk diffusion susceptibility testing interpretive criteria for lomefloxacin and norfloxacin using fluoroquinolone-resistant isolates. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:4 Topics: Anti-Infective Agents; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Quinolones; Sensitivity and Specificity	1995
The accumulation of fluoroquinolones in Staphylococcus aureus during the postantibiotic effect. The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:3 Topics: Anti-Infective Agents; Biotransformation; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Quinolones; Staphylococcus aureus	1994
In vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity. The Journal of infectious diseases, 1995, Volume: 171, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enterobacteriaceae; Fluoroquinolones; Norfloxacin; Ofloxacin; Proteus; Providencia; Quinolones; Surface Properties; Urea; Urease	1995
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials. Photodermatology, photoimmunology & photomedicine, 1994, Volume: 10, Issue:5 Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroquinolones; Humans; In Vitro Techniques; Lipid Peroxidation; Norfloxacin; Ofloxacin; Oxygen; Photochemistry; Photosensitivity Disorders; Quinolones; Sodium Azide; Squalene; Ultraviolet Rays	1994
Characterization of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:1 Topics: Anti-Infective Agents; Cations, Divalent; Fluoroquinolones; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Norfloxacin; Quinolones; X-Ray Diffraction	1993
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:11 Topics: Anti-Infective Agents; Ciprofloxacin; Diffusion; Drug Resistance, Microbial; Enoxacin; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin; Quinolones	1995
[Pharmacokinetics of norfloxacin and lomefloxacin in aqueous humour analysed by microdialysis]. Nippon Ganka Gakkai zasshi, 1996, Volume: 100, Issue:7 Topics: Animals; Anti-Infective Agents; Aqueous Humor; Fluoroquinolones; Microdialysis; Norfloxacin; Quinolones; Rabbits	1996
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells]. Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14, Issue:8 Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature	1996
Photocleavage of DNA by the fluoroquinolone antibacterials. Journal of photochemistry and photobiology. B, Biology, 1998, Aug-21, Volume: 45, Issue:1 Topics: Anti-Infective Agents; DNA Damage; Enoxacin; Fleroxacin; Fluoroquinolones; Nalidixic Acid; Norfloxacin; Photolysis; Plasmids; Quinolones; Structure-Activity Relationship; Ultraviolet Rays	1998
Structure and medium-dependent photodecomposition of fluoroquinolone antibiotics. Photochemistry and photobiology, 1998, Volume: 68, Issue:5 Topics: Anti-Infective Agents; Enoxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Photolysis; Photosensitizing Agents; Quantum Theory; Quinolones; Structure-Activity Relationship	1998
[The uptake of fluoroquinolone agent drugs by cultured human conjunctival epithelial cells and cultured SIRC rabbit corneal cells]. Nippon Ganka Gakkai zasshi, 1999, Volume: 103, Issue:8 Topics: Animals; Anti-Infective Agents; Cells, Cultured; Conjunctiva; Cornea; Epithelial Cells; Fluoroquinolones; Humans; Norfloxacin; Ofloxacin; Quinolones; Rabbits	1999
Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates. The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:6 Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; DNA Topoisomerase IV; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Drug Resistance, Multiple; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Lipopolysaccharides; Microbial Sensitivity Tests; Mutation; Norfloxacin; Quinolones	1999
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation. Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolones; Humans; Lipid Peroxidation; Norfloxacin; Ofloxacin; Quinolones; Reactive Oxygen Species; Squalene; Time Factors; Ultraviolet Rays	1999
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones. Journal of photochemistry and photobiology. B, Biology, 2000, Volume: 58, Issue:1 Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin	2000
[Degradation of liquid preparations of four fluoroquinolones by factorial experiment. ]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:12 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Light; Norfloxacin; Ofloxacin; Quinolones	1997
Studies on the uptake and release of fluoroquinolones by disposable contact lenses. The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 2001, Volume: 27, Issue:4 Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Contact Lenses, Hydrophilic; Disposable Equipment; Drug Delivery Systems; Fluoroquinolones; Norfloxacin; Ofloxacin; Quinolones	2001
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins	2002
Laser flash photolysis study of photoionization in fluoroquinolones. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2002, Volume: 1, Issue:11 Topics: Anti-Infective Agents; Electron Transport; Enoxacin; Fluoroquinolones; Lasers; Norfloxacin; Photochemistry; Photolysis; Photons; Quantum Theory; Quinolones; Solutions; Time Factors; Water	2002
Reliability of phototoxic tests of fluoroquinolones in vitro. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:5 Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Phototoxic; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Micronucleus Tests; Norfloxacin; Quinolones; Rats; Rats, Wistar; Ultraviolet Rays	2003
Effects of lomefloxacin and norfloxacin on pancreatic beta-cell ATP-sensitive K(+) channels. Life sciences, 2003, Jun-13, Volume: 73, Issue:4 Topics: Animals; Anti-Infective Agents; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Fluoroquinolones; Islets of Langerhans; Models, Chemical; Norfloxacin; Potassium Channels; Quinolinic Acid; Quinolones; Rats	2003
Binding characteristics of fluoroquinolones to synthetic levodopa melanin. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:8 Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol	2003
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes. Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:9 Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones	2003
Vibrational spectroscopic characterization of fluoroquinolones. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:7 Topics: Aza Compounds; Cinoxacin; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Enoxacin; Enzyme Inhibitors; Fluoroquinolones; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Models, Theoretical; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Oxolinic Acid; Quinolines; Quinolones; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Ultraviolet Rays; Vibration; Water	2005
The simultaneous separation and determination of five quinolone antibiotics using isocratic reversed-phase HPLC: application to stability studies on an ofloxacin tablet formulation. Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4 Topics: Anti-Bacterial Agents; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Industry; Drug Stability; Fluoroquinolones; Hydrogen-Ion Concentration; Models, Chemical; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones; Reproducibility of Results; Tablets; Time Factors	2005
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Clone Cells; Cross Reactions; Drug Hypersensitivity; Enoxacin; Female; Fluoroquinolones; Humans; Hypersensitivity, Delayed; Middle Aged; Moxifloxacin; Nalidixic Acid; Norfloxacin; Ofloxacin; Patch Tests; Pipemidic Acid; Quinolines; Quinolones; T-Lymphocytes	2006
Selective action of fluoroquinolones against intracellular amastigotes of Leishmania (Viannia) panamensis in vitro. The Journal of parasitology, 2005, Volume: 91, Issue:6 Topics: Animals; Cell Line; Cinoxacin; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Leishmania guyanensis; Macrophages; Nalidixic Acid; Norfloxacin; Ofloxacin; Quinolones	2005
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes. Acta ophthalmologica Scandinavica, 2006, Volume: 84, Issue:2 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution	2006
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares]. Guang pu xue yu guang pu fen xi = Guang pu, 2006, Volume: 26, Issue:1 Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood	2006
Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite. Chemosphere, 2007, Volume: 66, Issue:8 Topics: Absorption; Anti-Bacterial Agents; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Hydrogen-Ion Concentration; Iron Compounds; Kinetics; Minerals; Molecular Structure; Norfloxacin; Ofloxacin; Oxidation-Reduction	2007
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography, 2007, Volume: 25, Issue:4 Topics: Animals; Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2007
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures	2009
Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA. The Analyst, 2009, Volume: 134, Issue:9 Topics: DNA; Drug Interactions; Drug Synergism; Fluoroquinolones; Norfloxacin; Ofloxacin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	2009
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma. Biomedical chromatography : BMC, 2011, Volume: 25, Issue:5 Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity	2011
Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater. Journal of pharmaceutical and biomedical analysis, 2011, Jan-05, Volume: 54, Issue:1 Topics: Chemical Fractionation; Chemistry, Pharmaceutical; Chromatography, Liquid; Emulsions; Enrofloxacin; Ethane; Fluoroquinolones; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Methanol; Norfloxacin; Ofloxacin; Ultrasonics; Water Pollutants, Chemical; Water Purification	2011
[Preliminary study on occurrence and health risk assessment of quinolone antibiotics in vegetables from Guangzhou, China]. Huan jing ke xue= Huanjing kexue, 2010, Volume: 31, Issue:10 Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Food Contamination; Norfloxacin; Quinolones; Risk Assessment; Urban Health; Vegetables	2010
Simultaneous determination of norfloxacin and lomefloxacin in milk by first derivative synchronous fluorescence spectrometry using Al (III) as an enhancer. Analytica chimica acta, 2011, Nov-30, Volume: 707, Issue:1-2 Topics: Aluminum Compounds; Animals; Fluoroquinolones; Milk; Norfloxacin; Spectrometry, Fluorescence	2011
Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater. Water research, 2012, Oct-15, Volume: 46, Issue:16 Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Mass Spectrometry; Norfloxacin; Oxidation-Reduction; Ozone; Piperazine; Piperazines; Quinolones; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical	2012
Determination of five quinolone antibiotic residues in foods by micellar electrokinetic capillary chromatography with quantum dot indirect laser-induced fluorescence. Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:13 Topics: Animal Feed; Animals; Anti-Bacterial Agents; Cadmium Compounds; Chromatography, Micellar Electrokinetic Capillary; Ciprofloxacin; Enrofloxacin; European Union; Fluorescence; Fluoroquinolones; Hydrogen-Ion Concentration; Japan; Lasers; Limit of Detection; Loxapine; Norfloxacin; Quantum Dots; Quinolones; Spectrometry, Fluorescence; Tellurium	2014
[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing]. Huan jing ke xue= Huanjing kexue, 2014, Volume: 35, Issue:11 Topics: Anti-Bacterial Agents; China; Chromatography, High Pressure Liquid; Ciprofloxacin; Cities; Enrofloxacin; Fluoroquinolones; Norfloxacin; Ofloxacin; Soil; Soil Pollutants	2014
[Distribution Characteristics of Fluoroquinolones Antibiotics in Surface Water and Groundwater from Typical Areas in A City]. Huan jing ke xue= Huanjing kexue, 2015, Volume: 36, Issue:11 Topics: Anti-Bacterial Agents; Cities; Enrofloxacin; Environmental Monitoring; Fluoroquinolones; Groundwater; Norfloxacin; Ofloxacin; Rivers; Sewage; Water; Water Pollutants, Chemical	2015
[Development of Determination Method of Fluoroquinolone Antibiotics in Sludge Based on Solid Phase Extraction and HPLC-Fluorescence Detection Analysis]. Huan jing ke xue= Huanjing kexue, 2016, Apr-15, Volume: 37, Issue:4 Topics: Adsorption; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Norfloxacin; Ofloxacin; Sewage; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical	2016