norfloxacin has been researched along with fluconazole in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.23) | 18.2507 |
| 2000's | 5 (7.04) | 29.6817 |
| 2010's | 56 (78.87) | 24.3611 |
| 2020's | 7 (9.86) | 2.80 |
| Authors | Studies |
|---|---|
| Cortijo, J; Gálvez, J; García-Domenech, R; Morcillo, E; Ríos-Santamarina, I; Santamaria, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Balzarini, J; De Clercq, E; Judge, V; Kumar, P; Narang, R; Narasimhan, B; Sharma, D | 1 |
| Judge, V; Kumar, P; Narang, R; Narasimhan, B; Sharma, D | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendraprasad, Y; Sastry, BS; Sathisha, K; Suresh Kumar, GV | 1 |
| Akhtar, M; Alam, MM; Hasan, SM; Husain, A; Khanna, S; Zaman, MS | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chandrashekar, SM; Kistayya, C; Mallikarjuna, BP; Rajendraprasad, Y; Suresh Kumar, GV | 1 |
| Gan, LL; Zhang, FF; Zhou, CH | 1 |
| Fang, B; Rao, XC; Zhou, CH | 1 |
| Chandrashekar, SM; Mallikarjuna, BP; Rajendra Prasad, Y; Suresh Kumar, GV | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Mi, JL; Zhang, YY; Zhou, CH; Zhou, XD | 1 |
| Kumar, P; Majeed, AB; Mani, V; Mishra, RK; Narasimhan, B; Ramasamy, K; Sharma, SK | 1 |
| Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ; Teraiya, SB | 1 |
| Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ | 1 |
| Kaushik, CP; Kumar, A; Lal, K; Pavan, MS | 1 |
| Damu, GL; Geng, RX; Zhang, L; Zhang, SL; Zhou, CH | 1 |
| He, NQ; Huang, C; Lin, J; Tang, YJ; Wang, XH; Yan, SJ | 1 |
| Cui, SF; Damu, GL; Geng, RX; Peng, XM; Ren, Y; Zhang, SL; Zhou, CH | 1 |
| Cai, GX; Damu, GL; Zhang, HZ; Zhou, CH | 1 |
| Carocci, A; Carrieri, A; Catalano, A; Corbo, F; Defrenza, I; Franchini, C; Muraglia, M; Rosato, A; Van Bambeke, F | 1 |
| Chang, JJ; Damu, GL; Geng, RX; Zhang, L; Zhang, SL; Zhou, CH | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Jiang, JJ; Jiang, KM; Jin, Y; Li, K; Lin, J; Shi, LP; Tao, YH; Wang, XH | 1 |
| Geng, RX; Peng, XM; Rasheed, S; Yan, CY; Yin, BT; Zhang, SL; Zhou, CH | 1 |
| Kishore, B; Lv, JS; Peng, XM; Zhou, CH | 1 |
| Batchu, H; Batra, S; Mishra, A; Shukla, PK; Singh, P; Srivastava, K | 1 |
| Cai, GX; Cui, SF; Damu, GL; Peng, XM; Wen, QM; Zhou, CH | 1 |
| Cui, SF; Peng, LP; Rasheed, S; Vijaya Kumar, K; Zhang, HZ; Zhou, CH | 1 |
| Geng, RX; Kumar, KV; Zhang, L; Zhou, CH | 1 |
| Chopra, S; Kushwaha, P; Modukuri, RK; Pasupuleti, M; Rao, KB; Sashidhara, KV; Shukla, PK; Singh, P; Soni, I | 1 |
| Guo, M; Li, C; Li, YR; Liu, JC; Piao, HR; Sun, LP; Zhang, TY; Zheng, CJ | 1 |
| Addla, D; Cai, GX; Geng, RX; Li, S; Ponmani, J; Wang, A; Wang, YN; Xie, D; Zhang, L; Zhang, SL; Zhou, CH | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Avula, SR; Fang, XJ; Jeyakkumar, P; Zhou, CH; Zhou, Q | 1 |
| Avula, SR; Jeyakkumar, P; Wen, SQ; Zhang, L; Zhou, CH | 1 |
| Avula, SR; Jeyakkumar, P; Zhang, L; Zhou, CH | 1 |
| Addla, D; Avula, SR; Cheng, Y; Gao, WW; Lin, JM; Tangadanchu, VKR; Zhang, L; Zhou, CH | 1 |
| Chi, KQ; Liu, HY; Piao, HR; Sun, LP; Wei, ZY; Yu, ZK; Zheng, CJ | 1 |
| Cheng, Y; Geng, RX; Gopala, L; Jeyakkumar, P; Liu, HB; Peng, XM; Zhou, CH | 1 |
| Gan, LL; Gopala, L; He, SC; Peng, YJ; Tangadanchu, VKR; Zhang, HJ; Zhang, HZ; Zhou, CH | 1 |
| Gao, WW; Gopala, L; Li, ZZ; Tangadanchu, VKR; Zhou, CH | 1 |
| Gao, WW; Geng, RX; Liu, HB; Tangadanchu, VKR; Zhou, CH | 1 |
| Bheemanaboina, RRY; Gao, WW; Gopala, L; Li, S; Zhang, GB; Zhou, CH | 1 |
| Bejjanki, NK; Gandham, H; Kannekanti, VK; Katla, R; Maddili, SK; Tuniki, B; Zhou, CH | 1 |
| Bheemanaboina, RRY; Cai, GX; Wang, YN; Zhou, CH | 1 |
| Bheemanaboina, RRY; Cheng, Y; Tangadanchu, VKR; Zhang, Y; Zhou, CH | 1 |
| Bheemanaboina, RRY; Kannekanti, VK; Li, ZZ; Maddili, SK; Tangadanchu, VKR; Tuniki, B; Zhou, CH | 1 |
| Battini, N; Bheemanaboina, RRY; Fang, XF; Li, D; Tangadanchu, VKR; Zhou, CH | 1 |
| Battini, N; Bheemanaboina, RRY; Wang, LL; Zhang, SL; Zhou, CH | 1 |
| Zhang, B | 1 |
| Piao, HR; Sun, LP; Wu, J; Zhang, TY; Zheng, CJ | 1 |
| Du, H; Li, J; Liu, H; Piao, H; Sun, D; Sun, L; Zheng, C | 1 |
| Gao, F; Huang, G; Wang, T; Xiao, J | 1 |
| Ansari, MF; Battini, N; Bheemanaboina, RRY; Cai, GX; Chen, JP; Wang, LL; Xie, YP; Zhang, SL; Zhou, CH | 1 |
| Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J | 1 |
| Deng, Q; Ji, Q; Li, B; Shen, Y | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Ji, Q; Li, B; Shen, Y; Wu, H; Wu, X; Yuan, L | 1 |
| Mohammed, AAM; Okechukwu, PN; Shehadeh, MB; Suaifan, GARY | 1 |
| Beteck, RM; Jesumoroti, OJ; Legoabe, LJ; Patel, OPS | 1 |
| Sui, YF; Tangadanchu, VKR; Zhou, CH | 1 |
| Fang, B; Fawad Ansari, M; Li, D; Li, FF; Tan, YM; Zhou, CH | 1 |
| Bercy, P; De Beule, F; Ferrant, A | 1 |
| Broun, ER; Hromas, RA; Kneebone, PH; Sundblad, K; Tricot, G; Wheat, JL | 1 |
| Alshammari, AG; El-Gazzar, AR; Hafez, HN | 1 |
| Battini, N; Hu, YY; Yadav Bheemanaboina, RR; Zhou, CH | 1 |
| Ansari, MF; Bheemanaboina, RRY; Gan, LL; Li, D; Sui, YF; Wang, J; Zhou, CH | 1 |
| Almeida-Bezerra, JW; Barros, LM; Bezerra Morais-Braga, MF; Bezerra, JJL; Costa, AR; Coutinho, HDM; Fonseca, VJA; Lima, JPM; Pereira, RLS; Raposo, A; Rodrigues, FC; Sampaio, RSL; Santana, MDS; Santos, ATLD; Silva, MEPD; Silva, VBD | 1 |
6 review(s) available for norfloxacin and fluconazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Antibacterial activity study of 1,2,4-triazole derivatives.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities.
Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles | 2019 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiprotozoal Agents; Drug Development; Humans; Hypoglycemic Agents; Metronidazole | 2021 |
1 trial(s) available for norfloxacin and fluconazole
| Article | Year |
|---|---|
Randomized trial of the addition of gram-positive prophylaxis to standard antimicrobial prophylaxis for patients undergoing autologous bone marrow transplantation.
Topics: Acyclovir; Adult; Bacteremia; Bone Marrow Transplantation; Female; Fever; Fluconazole; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Neoplasms; Norfloxacin; Penicillins; Premedication; Streptococcal Infections; Vancomycin | 1994 |
64 other study(ies) available for norfloxacin and fluconazole
| Article | Year |
|---|---|
New bronchodilators selected by molecular topology.
Topics: Animals; Bronchodilator Agents; Discriminant Analysis; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Structure-Activity Relationship; Trachea | 1998 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Aspergillus niger; Bacillus subtilis; Candida albicans; Cells, Cultured; Chlorocebus aethiops; Drug Design; Escherichia coli; HeLa Cells; Herpesvirus 1, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vero Cells | 2009 |
Hansch analysis of substituted benzoic acid benzylidene/furan-2-yl-methylene hydrazides as antimicrobial agents.
Topics: Anti-Infective Agents; Benzylidene Compounds; Furans; Hydrazines; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship | 2009 |
Synthesis of new 4-isopropylthiazole hydrazide analogs and some derived clubbed triazole, oxadiazole ring systems--a novel class of potential antibacterial, antifungal and antitubercular agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Bacteria; Cell Line, Tumor; Cell Survival; Fungi; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles | 2009 |
Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: anti-inflammatory-analgesic and antimicrobial.
Topics: Amination; Analgesics; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Benzopyrans; Flavones; Fungi; Lipid Peroxidation; Methylation; Microbial Sensitivity Tests; Molecular Structure | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles | 2010 |
Synthesis, antibacterial and antifungal activities of some carbazole derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus fumigatus; Bacteria; Candida albicans; Carbazoles; Microbial Sensitivity Tests | 2010 |
Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents.
Topics: Amines; Anti-Bacterial Agents; Antifungal Agents; Azoles; Bacteria; Fungi; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Structure-Activity Relationship | 2010 |
Synthesis and pharmacological evaluation of clubbed isopropylthiazole derived triazolothiadiazoles, triazolothiadiazines and mannich bases as potential antimicrobial and antitubercular agents.
Topics: Anti-Infective Agents; Antitubercular Agents; Bacteria; Fungi; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Spectrophotometry, Infrared; Thiazoles | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Synthesis of novel fluconazoliums and their evaluation for antibacterial and antifungal activities.
Topics: Anti-Bacterial Agents; Antifungal Agents; Fluconazole; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared | 2011 |
Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl esters.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Survival; HCT116 Cells; Humans; Indoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Spectroscopy, Fourier Transform Infrared | 2012 |
An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones.
Topics: Anti-Infective Agents; Antioxidants; Azepines; Crystallography, X-Ray; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Conformation; Quinolines | 2012 |
An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines.
Topics: Antifungal Agents; Antitubercular Agents; Aspergillus fumigatus; Azo Compounds; Benzopyrans; Candida albicans; Crystallography, X-Ray; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Stereoisomerism; Thiosemicarbazones | 2012 |
Regioselective synthesis and antimicrobial studies of ester linked 1,4-disubstituted 1,2,3-bistriazoles.
Topics: Anti-Infective Agents; Bacteria; Binding Sites; Click Chemistry; Computer Simulation; Crystallography, X-Ray; DNA Gyrase; Esters; Fungi; Molecular Conformation; Protein Structure, Tertiary; Stereoisomerism; Triazoles | 2012 |
Synthesis and biological evaluation of novel benzimidazole derivatives and their binding behavior with bovine serum albumin.
Topics: Animals; Anti-Infective Agents; Bacteria; Benzimidazoles; Cattle; Chemistry Techniques, Synthetic; Fungi; Microbial Sensitivity Tests; Serum Albumin, Bovine; Thermodynamics | 2012 |
Synthesis and antimicrobial activity of polyhalo isophthalonitrile derivatives.
Topics: Anti-Infective Agents; Antifungal Agents; Candida albicans; Escherichia coli; Microbial Sensitivity Tests; Nitriles; Pseudomonas aeruginosa; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of a class of quinolone triazoles as potential antimicrobial agents and their interactions with calf thymus DNA.
Topics: Animals; Anti-Infective Agents; Bacteria; Cattle; DNA; DNA Replication; Drug Evaluation, Preclinical; Fungi; Intercalating Agents; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Quinolones; Spectrophotometry, Ultraviolet; Triazoles | 2013 |
Design, synthesis and antimicrobial evaluation of novel benzimidazole type of Fluconazole analogues and their synergistic effects with Chloromycin, Norfloxacin and Fluconazole.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Drug Synergism; Fluconazole; Fungi; Microbial Sensitivity Tests; Norfloxacin; Structure-Activity Relationship | 2013 |
2-Aminobenzothiazole derivatives: search for new antifungal agents.
Topics: Antifungal Agents; Benzothiazoles; Candida; Cell Line; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2013 |
Synthesis and bioactive evaluation of novel hybrids of metronidazole and berberine as new type of antimicrobial agents and their transportation behavior by human serum albumin.
Topics: Anti-Infective Agents; Bacteria; Berberine; Binding Sites; Biological Transport; Fungi; Humans; Magnetic Resonance Spectroscopy; Metronidazole; Molecular Structure; Serum Albumin; Thermodynamics | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and antimicrobial activity of polyhalobenzonitrile quinazolin-4(3H)-one derivatives.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Candida albicans; Candidiasis; Humans; Microbial Sensitivity Tests; Quinazolines | 2013 |
Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Cattle; Chalcones; DNA; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Serum Albumin; Triazoles | 2014 |
1,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Cattle; DNA; DNA Replication; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Naphthalimides; Serum Albumin; Static Electricity; Structure-Activity Relationship; Triazoles | 2014 |
Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Dose-Response Relationship, Drug; Ethers; Fungi; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2014 |
Synthesis and bioactive evaluation of a novel series of coumarinazoles.
Topics: Anti-Bacterial Agents; Antifungal Agents; Candida; Coumarins; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2014 |
Novel hybrids of metronidazole and quinolones: synthesis, bioactive evaluation, cytotoxicity, preliminary antimicrobial mechanism and effect of metal ions on their transportation by human serum albumin.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cattle; Cell Line; Cell Survival; DNA; Dose-Response Relationship, Drug; Fungi; Humans; Ions; Magnesium; Metronidazole; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quinolones; Serum Albumin; Structure-Activity Relationship | 2014 |
Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu(2+) mediated DNA-targeting antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Copper; DNA, Bacterial; Drug Evaluation, Preclinical; Fibroblasts; Fluoroquinolones; HEK293 Cells; Humans; Metronidazole; Mice; Microbial Sensitivity Tests; Molecular Targeted Therapy; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship | 2015 |
Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus.
Topics: | 2015 |
Synthesis and biological evaluation of 1,3-diaryl pyrazole derivatives as potential antibacterial and anti-inflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Drug Resistance, Multiple, Bacterial; Furans; Gram-Negative Bacteria; Gram-Positive Cocci; Ibuprofen; Indomethacin; Mice; Pyrazoles | 2015 |
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.
Topics: Anti-Bacterial Agents; Benzimidazoles; Binding Sites; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quinolones; Structure-Activity Relationship; Topoisomerase Inhibitors | 2016 |
Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzimidazoles; Dose-Response Relationship, Drug; Drug Design; Fluorouracil; Fungi; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2016 |
Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Berberine; Dose-Response Relationship, Drug; Down-Regulation; Drug Discovery; Fungi; Hep G2 Cells; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Reactive Oxygen Species; Structure-Activity Relationship | 2016 |
Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Bacteria; Benzimidazoles; Berberine; Cattle; Cell Membrane Permeability; Chemistry Techniques, Synthetic; DNA; Drug Design; Fungi; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Protein Conformation; Serum Albumin; Water | 2016 |
Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells.
Topics: Animals; Anti-Infective Agents; Biological Transport; Cattle; Cell Line; Cell Membrane Permeability; Chemistry Techniques, Synthetic; DNA; DNA Replication; DNA Topoisomerase IV; Drug Design; Kinetics; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Permeability; Quinolones | 2016 |
Synthesis and biological evaluation of chalcone derivatives containing aminoguanidine or acylhydrazone moieties.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Cell Line; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Guanidines; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Salmonella typhimurium; Structure-Activity Relationship | 2016 |
Novel benzimidazolyl tetrahydroprotoberberines: Design, synthesis, antimicrobial evaluation and multi-targeting exploration.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Benzimidazoles; Berberine Alkaloids; Cattle; DNA; Fungi; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycoses | 2017 |
Design, synthesis and antimicrobial evaluation of novel benzimidazole-incorporated sulfonamide analogues.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Benzimidazoles; Cattle; DNA; Dose-Response Relationship, Drug; Drug Design; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Serum Albumin; Structure-Activity Relationship; Sulfonamides | 2017 |
Discovery of novel nitroimidazole enols as Pseudomonas aeruginosa DNA cleavage agents.
Topics: Albumins; Anti-Bacterial Agents; DNA Cleavage; DNA Replication; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles; Pseudomonas aeruginosa; Quantum Theory; Structure-Activity Relationship | 2017 |
Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzimidazoles; Cattle; Cell Line; Cell Survival; DNA; Dose-Response Relationship, Drug; Drug Design; Fungi; Hep G2 Cells; Humans; Models, Molecular; Molecular Structure; Pyrimidines; Reactive Oxygen Species; Serum Albumin; Structure-Activity Relationship; Thermodynamics | 2018 |
Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Berberine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2018 |
Molecular interaction of novel benzothiazolyl triazolium analogues with calf thymus DNA and HSA-their biological investigation as potent antimicrobial agents.
Topics: Animals; Anti-Bacterial Agents; Bacillus subtilis; Benzothiazoles; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Escherichia coli; Humans; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Pseudomonas aeruginosa; Salmonella typhi; Serum Albumin; Structure-Activity Relationship; Triazoles | 2018 |
Novel purine benzimidazoles as antimicrobial agents by regulating ROS generation and targeting clinically resistant Staphylococcus aureus DNA groove.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Benzimidazoles; Candida albicans; Cell Line, Tumor; Cell Proliferation; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Purines; Reactive Oxygen Species; Structure-Activity Relationship | 2018 |
Novel carbazole-triazole conjugates as DNA-targeting membrane active potentiators against clinical isolated fungi.
Topics: Antifungal Agents; Candida; Carbazoles; DNA, Fungal; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles | 2018 |
Azoalkyl ether imidazo[2,1-b]benzothiazoles as potentially antimicrobial agents with novel structural skeleton.
Topics: Anti-Bacterial Agents; Antifungal Agents; Benzothiazoles; Dose-Response Relationship, Drug; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quantum Theory; Structure-Activity Relationship | 2018 |
Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant
Topics: | 2018 |
Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation.
Topics: Anti-Infective Agents; Bacteria; Cell Membrane Permeability; Chitin Synthase; DNA Gyrase; DNA Replication; Drug Design; Fungi; Intercalating Agents; Molecular Docking Simulation; Norfloxacin; Quantum Theory; Structure-Activity Relationship; Thiazoles | 2019 |
Synthesis of novel dihydrotriazine derivatives bearing 1,3-diaryl pyrazole moieties as potential antibacterial agents.
Topics: Anti-Bacterial Agents; Binding Sites; Cell Line; Cell Survival; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Protein Structure, Tertiary; Pyrazoles; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines | 2019 |
Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rhodanine; Structure-Activity Relationship; Tryptophan | 2019 |
A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV.
Topics: Anti-Bacterial Agents; DNA; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Design; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Oximes; Quantum Theory; Quinolones; Serum Albumin, Human; Staphylococcus aureus; Structure-Activity Relationship | 2019 |
Design, synthesis and biological evaluation of novel 5-(piperazin-1-yl)quinolin-2(1H)-one derivatives as potential chitin synthase inhibitors and antifungal agents.
Topics: Antifungal Agents; Aspergillus flavus; Candida albicans; Chitin Synthase; Cryptococcus neoformans; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Quinolones; Structure-Activity Relationship | 2019 |
Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1H)-quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents.
Topics: Antifungal Agents; Chemistry Techniques, Synthetic; Chitin Synthase; Drug Design; Drug Interactions; Enzyme Inhibitors; Quinolones | 2020 |
Design, synthesis and antimicrobial evaluation of novel glycosylated-fluoroquinolones derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Drug Design; Fluoroquinolones; Glycosylation; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Penicillium chrysogenum; Structure-Activity Relationship | 2020 |
Isatin-derived azoles as new potential antimicrobial agents: Design, synthesis and biological evaluation.
Topics: Anti-Bacterial Agents; Antifungal Agents; Azoles; Bacteria; Dose-Response Relationship, Drug; Drug Design; Fungi; Humans; Isatin; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2021 |
Pyrimidine-conjugated fluoroquinolones as new potential broad-spectrum antibacterial agents.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Norfloxacin; Pyrimidines | 2022 |
The effectiveness of a preventive regimen on the periodontal health of patients undergoing chemotherapy for leukemia and lymphoma.
Topics: Acyclovir; Amphotericin B; Ceftazidime; Chlorhexidine; Dental Plaque Index; Fluconazole; Humans; Immunosuppression Therapy; Ketoconazole; Leukemia; Lymphoma; Miconazole; Norfloxacin; Periodontal Diseases; Periodontal Index; Tooth Loss; Vancomycin | 1991 |
Facile heterocyclic synthesis and antimicrobial activity of polysubstituted and condensed pyrazolopyranopyrimidine and pyrazolopyranotriazine derivatives.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Drug Discovery; Fluconazole; Ganoderma; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mitosporic Fungi; Molecular Structure; Norfloxacin; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Triazines | 2015 |
Sulfonamide-Derived Four-Component Molecular Hybrids as Novel DNA-Targeting Membrane Active Potentiators against Clinical Escherichia coli.
Topics: Anti-Bacterial Agents; Antifungal Agents; Azoles; Carbonic Anhydrases; Cell Membrane Permeability; Cell Survival; DNA, Bacterial; Drug Compounding; Drug Resistance, Bacterial; Drug Resistance, Fungal; Drug Therapy, Combination; Escherichia coli; Ethanol; Fluconazole; Humans; Hydrogen Bonding; Isoenzymes; MCF-7 Cells; Metronidazole; Models, Molecular; Molecular Docking Simulation; Norfloxacin; Piperazine; Sulfonamides | 2019 |
Design and biological evaluation of a novel type of potential multi-targeting antimicrobial sulfanilamide hybrids in combination of pyrimidine and azoles.
Topics: A549 Cells; Anti-Infective Agents; Azoles; Cell Membrane Permeability; Cell Proliferation; DNA; DNA Gyrase; Drug Therapy, Combination; Enterococcus faecalis; Fluconazole; Humans; Intercalating Agents; Molecular Docking Simulation; Norfloxacin; Pyrimidines; Serum Albumin, Human; Structure-Activity Relationship; Sulfanilamide | 2020 |
Chemical composition and antimicrobial potential of Acrocomia aculeata (Jacq.) Lodd. ex Mart. and Syagrus cearensis Noblick (Arecaceae).
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Arecaceae; Candida albicans; Candida tropicalis; Escherichia coli; Fluconazole; Microbial Sensitivity Tests; Norfloxacin; Plant Oils; Staphylococcus aureus | 2023 |