norethindrone and tamoxifen

norethindrone has been researched along with tamoxifen in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199011 (40.74)18.7374
1990's7 (25.93)18.2507
2000's4 (14.81)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Jeng, MH; Jordan, VC; Parker, CJ1
Cardenas, M; García, GA; Garza-Flores, J; Menjívar, M; Pérez Palacios, G; Reynoso, M1
Jeng, MH; Jordan, VC1
Azuma, T; Mizumoto, R1
da Luz, RJ; Rubens, RD1
Mazella, J; Sun, B; Tseng, L1
Fujimoto, J; Fujita, H; Nakata, Y; Okada, H1
Beaugrand, M; Roudil, F; Trinchet, JC; Vaysse, J1
García, GA; Garza-Flores, J; Menjívar, M; Pérez-Palacios, G; Vilchis, F1
Donahoe, PK; Hutson, JM; MacLaughlin, DT1
Howell, A; Ribeiro, G1
Larrea, F; Moctezuma, O; Pérez-Palacios, G1
Asselain, B; Bretaudeau, B; Garcia-Giralt, E; Jouve, M; Magdelenat, H; Palangie, T; Pouillart, P1
Elder, MG; Lim, L; Marr, W; Moore, PA; White, JO1
Barbosa-Coutinho, LM; Dahlem, N; Orsi, V; Poy, M; Silva, IS; Spritzer, PM1
Gold, E; Goulding, A; Stapley, S1
Crews, D; Wibbels, T1
Ashley, S; Athanasiou, S; Bourne, T; Chang, J; Collins, W; Davey, J; Gruböck, K; Humphries, S; Oakes, L; Powles, TJ; Tidy, A; Viggers, J1
Avari, KM; Bhiwgade, DA; Borkar, MR1
Guzman, RC; Nandi, S; Rajkumar, L; Talamantes, F; Thordarson, G; Yang, J1
Franke, HR; Vermes, I; Werner, HM1

Trials

2 trial(s) available for norethindrone and tamoxifen

ArticleYear
[Metastatic breast cancer: controlled trial of chemotherapy with and without hormones].
    Bulletin du cancer, 1984, Volume: 71, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Norethindrone; Tamoxifen; Teniposide; Vincristine

1984
The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy post-menopausal women on tamoxifen or placebo.
    British journal of cancer, 1998, Volume: 78, Issue:2

    Topics: Aged; Breast Neoplasms; Double-Blind Method; Endometrium; Estrogen Antagonists; Female; Humans; Middle Aged; Norethindrone; Postmenopause; Tamoxifen; Ultrasonography

1998

Other Studies

25 other study(ies) available for norethindrone and tamoxifen

ArticleYear
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation.
    Cancer research, 1992, Dec-01, Volume: 52, Issue:23

    Topics: Amino Acid Sequence; Breast Neoplasms; Cell Division; Chloramphenicol O-Acetyltransferase; Dose-Response Relationship, Drug; Enzyme Induction; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Norethindrone; Norethynodrel; Norgestrel; Progesterone; Protein-Tyrosine Kinases; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1992
Further studies on the antigonadotropic mechanism of action of norethisterone.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:1

    Topics: Animals; Cyproterone; Cyproterone Acetate; Female; Follicle Stimulating Hormone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Norethindrone; Orchiectomy; Ovariectomy; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tamoxifen

1991
Growth stimulation and differential regulation of transforming growth factor-beta 1 (TGF beta 1), TGF beta 2, and TGF beta 3 messenger RNA levels by norethindrone in MCF-7 human breast cancer cells.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:8

    Topics: Breast Neoplasms; Cell Division; Estradiol; Gene Expression Regulation; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Norethindrone; Promegestone; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor beta; Tumor Cells, Cultured

1991
[Synthetic female hormones-induced liver cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: Spec No

    Topics: Animals; Carcinoma, Hepatocellular; Contraceptives, Oral, Synthetic; Estradiol Congeners; Ethinyl Estradiol; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Norethindrone; Norethindrone Acetate; Progesterone Congeners; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen

1989
Norethisterone acetate as secondary endocrine treatment in advanced breast cancer.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Middle Aged; Norethindrone; Norethindrone Acetate; Ovariectomy; Prednisolone; Tamoxifen

1989
Modulation of aromatase activity in human endometrial stromal cells by steroids, tamoxifen and RU 486.
    Endocrinology, 1986, Volume: 118, Issue:4

    Topics: Adult; Aromatase; Dexamethasone; Dose-Response Relationship, Drug; Endometrium; Estrenes; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Norethindrone; Progesterone; Progestins; Promegestone; Steroids; Tamoxifen; Testosterone; Time Factors

1986
[Hormone dependency and progestogen therapy in the treatment of endometrial cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Cell Division; Female; Humans; Hydroxyprogesterones; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Norethindrone; Tamoxifen; Tumor Stem Cell Assay; Uterine Neoplasms

1987
[Effects of a tamoxifen-norethisterone combination in 16 patients with hepatocellular carcinoma].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:5

    Topics: Aged; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Male; Middle Aged; Norethindrone; Tamoxifen

1985
A-ring reduction enhances the antigonadotropic potency of norethisterone.
    Acta endocrinologica, 1986, Volume: 112, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Isomerism; Luteinizing Hormone; Male; Norethindrone; Norethynodrel; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

1986
Steroid modulation of Mullerian duct regression in the chick embryo.
    General and comparative endocrinology, 1985, Volume: 57, Issue:1

    Topics: Aminoglutethimide; Androstenedione; Animals; Anti-Mullerian Hormone; Chick Embryo; Drug Interactions; Estrogen Antagonists; Estrogens; Female; Glycoproteins; Growth Inhibitors; Male; Mullerian Ducts; Norethindrone; Pyrrolidines; Tamoxifen; Testicular Hormones; Thiophenes

1985
Management of advanced carcinoma of the breast.
    The Practitioner, 1985, Volume: 229, Issue:1401

    Topics: Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Neoplasm Recurrence, Local; Norethindrone; Norethindrone Acetate; Tamoxifen

1985
Estrogen-like effects of norethisterone on the hypothalamic pituitary unit of ovariectomized rats.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:4A

    Topics: Animals; Castration; Estradiol; Estrogens; Female; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Kinetics; Luteinizing Hormone; Norethindrone; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Tamoxifen

1984
Comparative effects of progesterone, norgestrel, norethisterone and tamoxifen on the abnormal uterus of the anovulatory rat.
    The Biochemical journal, 1982, Oct-15, Volume: 208, Issue:1

    Topics: Animals; Anovulation; Estradiol; Female; Norethindrone; Norgestrel; Progesterone; Rats; Receptors, Estrogen; Subcellular Fractions; Tamoxifen; Uterus

1982
Effects of norethisterone acetate and tamoxifen on serum prolactin levels, uterine growth and on the presence of uterine immunoreactive prolactin in estradiol-treated ovariectomized rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1995, Volume: 28, Issue:1

    Topics: Animals; Estradiol; Female; Norethindrone; Norethindrone Acetate; Ovariectomy; Prolactin; Rats; Rats, Wistar; Tamoxifen; Uterus

1995
Tamoxifen and norethisterone: effects on plasma cholesterol and total body calcium content in the estrogen-deficient rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1994, Volume: 26, Issue:2

    Topics: Animals; Bone Diseases, Metabolic; Buserelin; Calcium; Cholesterol; Estradiol; Estrogens; Female; Norethindrone; Rats; Tamoxifen

1994
Steroid-induced sex determination at incubation temperatures producing mixed sex ratios in a turtle with TSD.
    General and comparative endocrinology, 1995, Volume: 100, Issue:1

    Topics: Animals; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Female; Male; Norethindrone; Sex Differentiation; Sex Ratio; Tamoxifen; Temperature; Testosterone; Turtles

1995
Fine structure of prolactin cell of female albino rat as affected by some antifertility drugs--a comparative electron microscopic study.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:2

    Topics: Animals; Contraceptive Agents; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Levonorgestrel; Microscopy, Electron; Norethindrone; Pituitary Gland; Progesterone; Prolactin; Rats; Rats, Wistar; Tamoxifen

2001
Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments.
    Breast cancer research : BCR, 2004, Volume: 6, Issue:1

    Topics: 2-Methoxyestradiol; Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Estradiol; Estriol; Estrogens; Ethinyl Estradiol; Female; Mammary Neoplasms, Animal; Megestrol Acetate; Methylnitrosourea; Norethindrone; Progesterone; Progestins; Rats; Rats, Inbred Lew; Tamoxifen; Time Factors; Treatment Outcome

2004
Apoptosis and proliferation in breast cancer cells, cultured in vitro: effects of SERMs.
    Climacteric : the journal of the International Menopause Society, 2005, Volume: 8, Issue:3

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Contraceptive Agents, Female; Dydrogesterone; Estradiol; Estrogen Replacement Therapy; Humans; Medroxyprogesterone Acetate; Norethindrone; Norethindrone Acetate; Norpregnenes; Progesterone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Tumor Cells, Cultured

2005