norethindrone and promegestone

norethindrone has been researched along with promegestone in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's6 (30.00)18.2507
2000's11 (55.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kollman, PA; Lee, DL; Marsh, FJ; Wolff, ME1
Doré, JC; Gilbert, J; Ojasoo, T; Raynaud, JP1
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Jeng, MH; Jordan, VC1
Band, V; Farooq, A; Kharbanda, SM; Murugesan, K1
Mazella, J; Sun, B; Tseng, L1
Joosten, JW; Kloosterboer, HJ; Schoonen, WG2
Greyling, MD; Potgieter, HC; van Aarde, RJ1
Bouchoux, F; Degryse, M; Gaillard, M; Lecaque, D; Petit, F; Philibert, D1
Al-Azzawi, F; Thompson, J; Wahab, M1
al-Azzawi, F; Dillon, J; Hirvonen, E; Magaril, C; Pornel, B; Thompson, J; van der Mooren, MJ; Wahab, M; Ylikorkala, O1
García-Becerra, R; Gutiérrez-Sagal, R; Pasapera, AM; Savouret, JF; Ulloa-Aguirre, A1
Dehennin, L; Jondet, M1
Al-Azzawi, F; Proudler, AJ; Sami, S; Stevenson, J; Thompson, J; Wahab, M1
Shirk, RA; Winneker, RC; Zhang, Z1
Gambacciani, M; Genazzani, AR; Spielmann, D1
Pornel, B; Spielmann, D1
Koninckx, PR; Spielmann, D1
Bouchard, P; De Cicco-Nardone, F; Garcea, N; Spielmann, D1

Trials

7 trial(s) available for norethindrone and promegestone

ArticleYear
Effect of different cyclical sequential progestins on endometrial vascularity in postmenopausal women compared with the natural cycle: a morphometric analysis.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:10

    Topics: Adult; Antigens, CD34; Dose-Response Relationship, Drug; Double-Blind Method; Endometrium; Female; Hormone Replacement Therapy; Humans; Menstrual Cycle; Middle Aged; Norethindrone; Postmenopause; Progestins; Promegestone; Reference Values

2000
Acceptability and patterns of endometrial bleeding in estradiol-based HRT regimens: a comparative study of cyclical sequential combinations of trimegestone or norethisterone acetate.
    Climacteric : the journal of the International Menopause Society, 2001, Volume: 4, Issue:4

    Topics: Argentina; Double-Blind Method; Endometrium; Estradiol; Estrogen Replacement Therapy; Europe; Female; Hot Flashes; Humans; Middle Aged; Norethindrone; Norethindrone Acetate; Patient Satisfaction; Promegestone; Treatment Outcome; Uterine Hemorrhage

2001
Randomized trial of effects of estradiol in combination with either norethisterone acetate or trimegestone on lipids and lipoproteins in postmenopausal women.
    Climacteric : the journal of the International Menopause Society, 2004, Volume: 7, Issue:3

    Topics: Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; England; Estradiol; Estrogen Replacement Therapy; Female; Humans; Lipoprotein(a); Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Promegestone

2004
Efficacy on climacteric symptoms of a continuous combined regimen of 1 mg 17beta-estradiol and trimegestone versus two regimens combining 1 or 2 mg 17beta-estradiol and norethisterone acetate.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Affect; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Estradiol; Estrogen Replacement Therapy; Female; Hot Flashes; Humans; Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Promegestone; Prospective Studies; Quality of Life; Sweating

2005
A study of the control of climacteric symptoms in postmenopausal women following sequential regimens of 1 mg 17beta-estradiol and trimegestone compared with a regimen containing 1 mg estradiol valerate and norethisterone over a two-year period.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Estradiol; Estrogen Replacement Therapy; Female; Hot Flashes; Humans; Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Promegestone; Prospective Studies; Quality of Life; Sleep Wake Disorders; Sweating; Uterine Hemorrhage

2005
A comparative 2-year study of the effects of sequential regimens of 1 mg 17beta-estradiol and trimegestone with a regimen containing estradiol valerate and norethisterone on the bleeding profile and endometrial safety in postmenopausal women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:2

    Topics: Administration, Oral; Adult; Body Weight; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Endometrial Hyperplasia; Endometrium; Estradiol; Estrogen Replacement Therapy; Female; Humans; Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Promegestone; Prospective Studies; Uterine Hemorrhage

2005
Bleeding profile and endometrial safety of continuous combined regimens 1 mg 17beta-estradiol/trimegestone versus 1 or 2 mg 17beta-estradiol/norethisterone acetate in postmenopausal women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:3

    Topics: Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Endometrium; Estradiol; Estrogen Replacement Therapy; Europe; Female; Humans; Israel; Menstrual Cycle; Middle Aged; Norethindrone; Norethindrone Acetate; Postmenopause; Promegestone; Treatment Outcome; Uterine Hemorrhage

2005

Other Studies

13 other study(ies) available for norethindrone and promegestone

ArticleYear
Quantitative relationships between steroid structure and binding to putative progesterone receptors.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:9

    Topics: Androstenes; Animals; Guinea Pigs; Humans; Hydroxyprogesterones; Protein Binding; Rabbits; Receptors, Progesterone; Sheep; Steroids; Structure-Activity Relationship

1977
Binding of steroids to the progestin and glucocorticoid receptors analyzed by correspondence analysis.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Animals; Cells, Cultured; Enzyme Induction; Glucocorticoids; Male; Rabbits; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Progesterone; Receptors, Steroid; Steroids; Tyrosine Transaminase

1988
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
Growth stimulation and differential regulation of transforming growth factor-beta 1 (TGF beta 1), TGF beta 2, and TGF beta 3 messenger RNA levels by norethindrone in MCF-7 human breast cancer cells.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:8

    Topics: Breast Neoplasms; Cell Division; Estradiol; Gene Expression Regulation; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Norethindrone; Promegestone; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor beta; Tumor Cells, Cultured

1991
Modulation of steroid production in goat ovarian cells: effect of progestins and antiprogestins.
    Endocrine research, 1990, Volume: 16, Issue:2

    Topics: Androstenedione; Androstenols; Animals; Corpus Luteum; Estradiol; Estrenes; Female; Follicle Stimulating Hormone; Gestrinone; Goats; Granulosa Cells; Nandrolone; Norethindrone; Progesterone; Progesterone Congeners; Progestins; Promegestone

1990
Modulation of aromatase activity in human endometrial stromal cells by steroids, tamoxifen and RU 486.
    Endocrinology, 1986, Volume: 118, Issue:4

    Topics: Adult; Aromatase; Dexamethasone; Dose-Response Relationship, Drug; Endometrium; Estrenes; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Norethindrone; Progesterone; Progestins; Promegestone; Steroids; Tamoxifen; Testosterone; Time Factors

1986
Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: I. MCF-7 cell lines.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Desogestrel; Estradiol; Estrogen Antagonists; Female; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Models, Statistical; Nandrolone; Norethindrone; Norpregnenes; Pregnanes; Pregnenediones; Progesterone; Promegestone; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Tumor Cells, Cultured

1995
Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Breast Neoplasms; Carcinoma; Cell Division; Desogestrel; Dose-Response Relationship, Drug; Estradiol; Estrenes; Estrogen Antagonists; Female; Furans; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Nandrolone; Norethindrone; Norpregnenes; Pregnanes; Pregnenediones; Progesterone; Promegestone; Tumor Cells, Cultured

1995
Ligand specificity of uterine oestrogen and progesterone receptors in the subadult African elephant, Loxodonta africana.
    Journal of reproduction and fertility, 1997, Volume: 109, Issue:2

    Topics: Animals; Binding, Competitive; Elephants; Female; Hormone Antagonists; Ligands; Mifepristone; Norethindrone; Progesterone; Progesterone Congeners; Promegestone; Protein Binding; Radioligand Assay; Receptors, Estrogen; Receptors, Progesterone; Sexual Maturation; Tritium

1997
The pharmacological profile of a novel norpregnance progestin (trimegestone).
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1999, Volume: 13, Issue:5

    Topics: Administration, Oral; Administration, Topical; Animals; Binding, Competitive; Endometrium; Female; Humans; Injections, Subcutaneous; Levonorgestrel; Medroxyprogesterone; Mice; Norethindrone; Norpregnenes; Progesterone Congeners; Promegestone; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Progesterone; Specific Pathogen-Free Organisms; Uterus

1999
Transactivation of progestin- and estrogen-responsive promoters by 19-nor progestins in African Green Monkey Kidney CV1 cells.
    Endocrine, 2001, Volume: 16, Issue:3

    Topics: Animals; Binding, Competitive; Cell Line; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; Estrogens; Gene Expression; Genes, Reporter; Genetic Vectors; Kidney; Levonorgestrel; Mifepristone; Norethindrone; Norpregnenes; Progestins; Promegestone; Promoter Regions, Genetic; Rabbits; Receptors, Progesterone; Response Elements; Transcriptional Activation; Transfection

2001
Impact of different progestins on endometrial vascularisation of postmenopausal women. A retrospective image analysis-morphometric study.
    Maturitas, 2003, Nov-20, Volume: 46, Issue:3

    Topics: Administration, Cutaneous; Administration, Intranasal; Case-Control Studies; Chlormadinone Acetate; Drug Administration Schedule; Endometrium; Estradiol; Female; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Microcirculation; Middle Aged; Norethindrone; Postmenopause; Progesterone; Promegestone

2003
Differential effects of estrogens and progestins on the anticoagulant tissue factor pathway inhibitor in the rat.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:4

    Topics: Androstenes; Animals; Antithrombins; Blood Coagulation; Cholesterol; Estrogens; Ethinyl Estradiol; Female; Humans; Lipoproteins; Models, Animal; Norethindrone; Norethindrone Acetate; Norethynodrel; Ovariectomy; Progestins; Promegestone; Rats; Rats, Sprague-Dawley

2005