norethindrone and phenobarbital

norethindrone has been researched along with phenobarbital in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bolt, HM; Kappus, H1
Back, DJ; Breckenridge, AM; Gay, FE; Rowe, PH; Smith, E1
Blakey, DC; White, IN1
Böhm, W; Carol, W; Hempel, E; Klinger, G1
Bellward, GD; Morgan, RG; Szombathy, VH1
Hüthwohl, B; Kahl, GF; Kahl, R; Tüttenberg, KH1
Cook, CE; Freudenthal, RI; Rosenfeld, R; Twine, M; Wall, ME1
Cosmides, GJ1
Conney, AH; Levin, W; Welch, RM1
Back, DJ; Macnee, CM; Orme, ML; Rowe, PH; Smith, E1
Back, DJ; Breckenridge, AM; Crawford, F; Cross, K; MacIver, M; Orme, ML; Rowe, PH; Smith, E1
Back, DJ; Breckenridge, AM; Crawford, FE; Orme, ML; Rowe, PH1
Back, DJ; Bates, M; Bowden, A; Breckenridge, AM; Hall, MJ; Jones, H; MacIver, M; Orme, M; Perucca, E; Richens, A; Rowe, PH; Smith, E1

Reviews

1 review(s) available for norethindrone and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

17 other study(ies) available for norethindrone and phenobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Irreversible protein binding of norethisterone (norethindrone) epoxide.
    Steroids, 1976, Volume: 27, Issue:1

    Topics: Animals; Cattle; Cytosol; Epoxy Compounds; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Norethindrone; Phenobarbital; Protein Binding; Rats; Serum Albumin, Bovine; Xanthine Oxidase

1976
The pharmacokinetics of norethisterone in the rabbit and rat after systemic and oral administration: effect of phenobarbitone [proceedings].
    British journal of pharmacology, 1977, Volume: 60, Issue:2

    Topics: Administration, Oral; Animals; Drug Interactions; Female; Injections, Intravenous; Kinetics; Norethindrone; Phenobarbital; Rabbits; Rats

1977
Destruction of cytochrome P-450 and formation of green pigments by contraceptive steroids in rat hepatocyte suspensions.
    Biochemical pharmacology, 1986, May-01, Volume: 35, Issue:9

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Humans; Liver; Male; Methylcholanthrene; Norethindrone; Phenobarbital; Pigments, Biological; Proadifen; Rats; Rats, Inbred F344; Steroids; Structure-Activity Relationship; Suspensions; Time Factors

1986
[Enzyme induction by drugs and hormonal contraception].
    Zentralblatt fur Gynakologie, 1973, Oct-12, Volume: 95, Issue:41

    Topics: Adult; Analgesics; Anti-Bacterial Agents; Anticonvulsants; Biopsy; Chlormadinone Acetate; Contraceptives, Oral; Drug Interactions; Endometrium; Enzyme Induction; Female; Humans; Mestranol; Norethindrone; Phenobarbital; Pregnancy; Sulfonamides; Tranquilizing Agents; Uterine Hemorrhage

1973
The effects of pretreatment of mice with norethindrone on the metabolism of 14C-imipramine by the liver microsomal drug-metabolizing enzymes.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cobalt; Cytochrome c Group; Cytochrome Reductases; Dealkylation; Desipramine; Female; Hydrogen-Ion Concentration; Hydroxylation; Imipramine; Methylcholanthrene; Mice; Microsomes, Liver; NADP; Norethindrone; Oxides; Phenobarbital; Proadifen; Time Factors

1974
Effects of synthetic progestagens on drug metabolism in rat liver microsomes.
    Biochemical pharmacology, 1974, Jul-15, Volume: 23, Issue:14

    Topics: Aerobiosis; Allyl Compounds; Aniline Compounds; Animals; Anisoles; Dealkylation; Estranes; Hydroxylation; Hydroxysteroids; In Vitro Techniques; Kinetics; Lynestrenol; Male; Microsomes, Liver; Nitro Compounds; Norethindrone; Norgestrel; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Progestins; Rats; Spectrophotometry

1974
Metabolism of norethynodrel by rat liver.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Alcohols; Animals; Biotransformation; Capillaries; Cattle; Chromatography, Gas; Chromatography, Thin Layer; Enzyme Induction; Escherichia coli; Glucuronidase; Hydroxylation; In Vitro Techniques; Ketosteroids; Liver; Male; Microsomes, Liver; Norethindrone; Norethynodrel; Oxidation-Reduction; Phenobarbital; Pregnanes; Rats; Snails; Subcellular Fractions; Sulfatases; Time Factors; Tritium

1971
Pharmacology-toxicology.
    Science (New York, N.Y.), 1970, May-22, Volume: 168, Issue:3934

    Topics: Antidepressive Agents; Blood Pressure; Brain; Contraceptives, Oral; Cytochromes; Desipramine; Diazepam; Endoplasmic Reticulum; Histamine; Lidocaine; Liver; Methylphenidate; Methyltyrosines; National Institutes of Health (U.S.); Norepinephrine; Norethindrone; Nortriptyline; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Placenta; Progesterone; Smoking; United States

1970
Decreased uterotropic potency of oral contraceptives in rats pretreated with phenobarbital.
    Endocrinology, 1968, Volume: 83, Issue:1

    Topics: Animals; Carbon Isotopes; Contraceptives, Oral; Diethylstilbestrol; Ethinyl Estradiol; Female; Liver; Mestranol; Microsomes; Norethindrone; Norethynodrel; Organ Size; Phenobarbital; Rats; Tritium; Uterus

1968
An investigation of the effects of phenobarbitone on the pharmacokinetics of norethindrone in the rat using liver perfusion and everted gut sacs.
    Biochemical pharmacology, 1984, May-15, Volume: 33, Issue:10

    Topics: Animals; Enzyme Induction; Female; Ileum; In Vitro Techniques; Kinetics; Liver; Norethindrone; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains

1984
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.
    Ciba Foundation symposium, 1980, Volume: 76

    Topics: Animals; Antipyrine; Contraceptives, Oral; Environment; Ethinyl Estradiol; Female; Half-Life; Humans; Intestinal Mucosa; Jejunum; Kinetics; Norethindrone; Norgestrel; Phenobarbital; Rats; Rifampin

1980
Phenobarbitone interaction with oral contraceptive steroids in the rabbit and rat.
    British journal of pharmacology, 1980, Volume: 69, Issue:3

    Topics: Animals; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Digestive System; Drug Interactions; Enzyme Induction; Ethinyl Estradiol; Female; Kinetics; Norethindrone; Phenobarbital; Rabbits; Rats; Sleep; Time Factors

1980
The interaction of phenobarbital and other anticonvulsants with oral contraceptive steroid therapy.
    Contraception, 1980, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Contraceptives, Oral; Drug Interactions; Ethinyl Estradiol; Female; Gonadal Steroid Hormones; Humans; Norethindrone; Norgestrel; Phenobarbital; Prospective Studies; Retrospective Studies

1980