norethindrone and methotrexate

norethindrone has been researched along with methotrexate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Begent, RH; Hayward, JL; Knight, RK; Rubens, RD; Sexton, SA1
Edelstyn, GA; MacRae, KD2
Aherne, GW; English, J; Marks, V1
Dendy, PP1
Kerl, H; Klein, G; Sandhofer, M1
Edelstyn, GA; Marcrae, KD1
Asselain, B; Bretaudeau, B; Garcia-Giralt, E; Jouve, M; Magdelenat, H; Palangie, T; Pouillart, P1

Trials

2 trial(s) available for norethindrone and methotrexate

ArticleYear
Combined cytotoxic and progestogen therapy for advanced breast cancer.
    Cancer, 1978, Volume: 42, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Heart Failure; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Norethindrone; Remission, Spontaneous; Time Factors; Vincristine

1978
[Metastatic breast cancer: controlled trial of chemotherapy with and without hormones].
    Bulletin du cancer, 1984, Volume: 71, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Norethindrone; Tamoxifen; Teniposide; Vincristine

1984

Other Studies

13 other study(ies) available for norethindrone and methotrexate

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
"Early" and "late" breast cancer: a unified concept for treatment.
    Clinical radiology, 1976, Volume: 27, Issue:4

    Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hypophysectomy; Methotrexate; Neoplasm Metastasis; Norethindrone; Time Factors; Vincristine

1976
The role of immunoassay in the analysis of microcontaminants in water samples.
    Ecotoxicology and environmental safety, 1985, Volume: 9, Issue:1

    Topics: Ethinyl Estradiol; Hospitals; Immunoassay; Methotrexate; Norethindrone; Progesterone; Sewage; Steroids; Water Pollutants; Water Pollutants, Chemical; Water Supply

1985
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine

1968
[Treatment of "collagen and autoimmune" diseases (author's transl)].
    Wiener klinische Wochenschrift, 1973, Nov-23, Volume: 85, Issue:47

    Topics: Adolescent; Adult; Aminobenzoates; Azathioprine; Chloroquine; Cyclophosphamide; Dermatomyositis; Dextrans; Female; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Norethindrone; Penicillamine; Pregnanes; Scleroderma, Localized; Scleroderma, Systemic

1973
Cyclical combination chemotherapy in advanced breast cancer.
    British journal of cancer, 1973, Volume: 28, Issue:5

    Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Hypophysectomy; Methotrexate; Norethindrone; Remission, Spontaneous; Time Factors; Vincristine

1973
Cyclical combination chemotherapy in advanced breast cancer.
    Annals of the Royal College of Surgeons of England, 1974, Volume: 54, Issue:6

    Topics: Age Factors; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hypophysectomy; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Norethindrone; Vincristine

1974